| Entry |
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| Name |
Progesterone;
4-Pregnene-3,20-dione
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| Formula |
C21H30O2
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| Exact mass |
314.2246
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| Mol weight |
314.4617
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| Structure |
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| Remark |
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| Reaction |
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| Pathway |
| map04080 | Neuroactive ligand-receptor interaction |
| map04914 | Progesterone-mediated oocyte maturation |
| map04925 | Aldosterone synthesis and secretion |
| map04927 | Cortisol synthesis and secretion |
| map05207 | Chemical carcinogenesis - receptor activation |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
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| Module |
| M00107 | Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone |
| M00108 | C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone |
| M00109 | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone |
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| Network |
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| Enzyme |
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| Brite |
Compounds with biological roles [BR:br08001]
Steroids
21-Carbon atoms
Pregnane derivatives
C00410 Progesterone
Hormones and transmitters
Steroid hormones
Progestagens
C00410 Progesterone
Lipids [BR:br08002]
ST Sterol lipids
ST02 Steroids
ST0203 C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives
C00410 Progesterone
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03D PROGESTOGENS
G03DA Pregnen (4) derivatives
G03DA04 Progesterone
D00066 Progesterone (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Progestins
Progesterone
D00066 Progesterone (JP18/USP/INN)
Infertility Agents
Progesterone
D00066 Progesterone (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
247 Estrogen and progesterone preparations
2477 Progesterones
D00066 Progesterone (JP18/USP/INN)
Animal drugs in Japan [BR:br08331]
94 Agents for breeding
941 Hormone preparations (except posterior-pituitary hormone and preparations)
9415 Luteinizing hormone and preparations
C00410 Progesterone
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
D00066 Progesterone
DG01666 Progesterone receptor agonist
D00066 Progesterone
Metabolizing enzyme substrate
DG01639 CYP2C19 substrate
D00066 Progesterone
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00066 Progesterone
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG02004 Progesterone
D00066 Progesterone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D00066 Progesterone (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00066 Progesterone
D00066 Progesterone injection
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00066
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 C1y C 23.0350 -18.9936
2 C1y C 24.2088 -19.6769
3 C1z C 21.8554 -19.6827
4 C1x C 23.0233 -17.6271
5 C1y C 25.4002 -18.9819
6 C1x C 24.1913 -21.0784
7 C2y C 21.8554 -21.0375
8 C1x C 20.6873 -19.0112
9 C1a C 21.8437 -18.2754
10 C1x C 24.2030 -16.9322
11 C1z C 25.4060 -17.6097
12 C1x C 27.7653 -18.9936
13 C1x C 23.0409 -21.7092
14 C2x C 20.6873 -21.7150
15 C1x C 19.5194 -19.6827
16 C1y C 26.5974 -16.9263
17 C1a C 25.3943 -16.2081
18 C1x C 27.7712 -17.6213
19 C5x C 19.5194 -21.0375
20 C5a C 26.6032 -15.5948
21 O5x O 18.3690 -21.6975
22 C1a C 25.3885 -14.8823
23 O5a O 27.8121 -14.8882
BOND 26
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 2
14 8 15 1
15 11 16 1
16 11 17 1 #Up
17 12 18 1
18 14 19 1
19 16 20 1 #Up
20 19 21 2
21 20 22 1
22 20 23 2
23 7 13 1
24 10 11 1
25 15 19 1
26 16 18 1
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