 | | DRUG: Elagolix, estradiol and norethisterone | |
| Entry |
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| Name |
Elagolix, estradiol and norethisterone;
Oriahnn (TN) |
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| Product |
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| Component |
Elagolix sodium [DR: D09336], Ethinyl estradiol [DR: D00554], Norethindrone acetate [DR: D00953]
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| Class |
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| Remark |
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| Efficacy |
Anti-endometriosis |
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| Disease |
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| Comment |
Elagolix is metabolized by CYP3A with some contribution from CYP2D6, CYP2C8 and uridine glucuronosyl transferases (UGTs).
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| Metabolism |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
H01C HYPOTHALAMIC HORMONES
H01CC Anti-gonadotropin-releasing hormones
H01CC53 Elagolix, estradiol and norethisterone
D12137 Elagolix, estradiol and norethisterone <US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers), Other
Elagolix/ Estradiol/ Norethindrone
D12137 Elagolix, estradiol and norethisterone
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG02918 CYP2C8 substrate
D12137 Elagolix, estradiol and norethisterone
DG01644 CYP2D6 substrate
D12137 Elagolix, estradiol and norethisterone
DG01633 CYP3A/CYP3A4 substrate
D12137 Elagolix, estradiol and norethisterone
DG02924 UGT substrate
D12137 Elagolix, estradiol and norethisterone
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D12137
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| Other DBs |
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| LinkDB |
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