KEGG   DRUG: Lidocaine and prilocaine
Entry
D02740            Mixture   Drug                                   

Name
Lidocaine and prilocaine;
Lidocaine and propitocaine;
Emla (TN);
Oraqix (TN);
Lidocaine and prilocaine (TN)
Product
  Generic
LIDOCAINE AND PRILOCAINE (Actavis Pharma), LIDOCAINE AND PRILOCAINE (Amneal Pharmaceuticals of New York LLC), LIDOCAINE AND PRILOCAINE (E. Fougera & Co. a division of Fougera Pharmaceuticals), LIDOCAINE AND PRILOCAINE (Hi-Tech Pharmacal), LIDOCAINE AND PRILOCAINE (MAJOR Pharmaceuticals), LIDOCAINE AND PRILOCAINE (NuCare Pharamceuticals), LIDOCAINE AND PRILOCAINE (Proficient Rx LP), APRIZIO PAK (PureTek Corporation), DERMACINRX EMPRICAINE (PureTek Corporation), DERMACINRX EMPRICAINE II (PureTek Corporation), NUVAKAAN II (PureTek Corporation), APRIZIO PAK II (PureTek Corporation), NUVAKAAN (PureTek Corporation), DERMACINRX PRIZOPAK (PureTek Corporation), LIDO-PRILO CAINE PACK (TMIG), LIDOCAINE AND PRILOCAINE (Teligent Pharma), LIDOCAINE AND PRILOCAINE CREAM (SOLA Pharmaceuticals), PRILO PATCH (PureTek Corporation), PRIZOTRAL II (PureTek Corporation), PRIZOTRAL (PureTek Corporation)
Component
Lidocaine [DR:D00358], Prilocaine [DR:D00553]
Remark
Therapeutic category: 1219
ATC code: N01BB52 N01BB54
Product: D02740<JP/US>
Efficacy
Anesthetic (topical)
Comment
Lidocaine is primarily metabolized by CYP1A2 and CYP3A4.
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01B ANESTHETICS, LOCAL
    N01BB Amides
     N01BB52 Lidocaine, combinations
      D02740  Lidocaine and prilocaine <JP/US>
     N01BB54 Prilocaine, combinations
      D02740  Lidocaine and prilocaine <JP/US>
USP drug classification [BR:br08302]
 Anesthetics
  Local Anesthetics
   Lidocaine/ Prilocaine
    D02740  Lidocaine and prilocaine
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   121  Local anesthetics
    1219  Others
     D02740  Lidocaine and prilocaine
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D02740
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D02740
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D02740
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D02740
Other DBs
CAS: 101362-25-8
PubChem: 47205816
LinkDB

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