KEGG   DRUG: Lidocaine and prilocaine
Entry
D02740            Mixture   Drug                                   

Name
Lidocaine and prilocaine;
Lidocaine and propitocaine;
Emla (TN);
Oraqix (TN);
Lidocaine and prilocaine (TN)
Product
  Generic
Component
Lidocaine [DR:D00358], Prilocaine [DR:D00553]
Remark
Therapeutic category: 1219
ATC code: N01BB52 N01BB54
Product: D02740<JP/US>
Efficacy
Anesthetic (topical)
Comment
Lidocaine is primarily metabolized by CYP1A2 and CYP3A4.
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01B ANESTHETICS, LOCAL
    N01BB Amides
     N01BB52 Lidocaine, combinations
      D02740  Lidocaine and prilocaine <JP/US>
     N01BB54 Prilocaine, combinations
      D02740  Lidocaine and prilocaine <JP/US>
USP drug classification [BR:br08302]
 Anesthetics
  Local Anesthetics
   Lidocaine/ Prilocaine
    D02740  Lidocaine and prilocaine
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   121  Local anesthetics
    1219  Others
     D02740  Lidocaine and prilocaine
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D02740
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D02740
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D02740
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D02740
Other DBs
CAS: 101362-25-8
PubChem: 47205816
LinkDB

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