KEGG   DRUG: Acyclovir sodiumHelp
Entry
D02764                      Drug                                   

Name
Acyclovir sodium (USAN);
Zovirax (TN)
Product
  Generic
Formula
C8H10N5O3. Na
Exact mass
247.0681
Mol weight
247.1865
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antiviral
 DG02840  Herpesvirus DNA polymerase inhibitor
Transporter substrate
 DG02858  SLC22A1 (OCT1) substrate
 DG02859  SLC22A6 (OAT1) substrate
 DG02860  SLC22A8 (OAT3) substrate
Remark
ATC code: D06BB03 J05AB01 S01AD03
Chemical structure group: DG00406
Product (DG00406): D00222<JP/US> D02764<US>
Efficacy
Antiviral, DNA polymerase inhibitor
  Disease
Herpes simplex infection [DS:H00365]
Varicella-zoster infections [DS:H00366]
Target
Herpesvirus DNA polymerase [KO:K18964]
Metabolism
Transporter: SLC22A1 [HSA:6580], SLC22A6 [HSA:9356], SLC22A8 [HSA:9376]
Interaction
Drug interaction
Structure map
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
    D06BB Antivirals
     D06BB03 Aciclovir
      D02764  Acyclovir sodium (USAN) <US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB01 Aciclovir
      D02764  Acyclovir sodium (USAN) <US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD03 Aciclovir
      D02764  Acyclovir sodium (USAN) <US>
USP drug classification [BR:br08302]
 Antivirals
  Antiherpetic Agents
   Acyclovir
    D02764  Acyclovir sodium (USAN)
 Dermatological Agents
  Topical Anti-infectives
   Antivirals, dermatological
    Acyclovir
     D02764  Acyclovir sodium (USAN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Aciclovir
    D02764  Acyclovir sodium (USAN)
Antiinfectives [br08350.html]
 Antivirals
  D02764
BRITE hierarchy
Other DBs
CAS: 69657-51-8
PubChem: 17396922
ChEMBL: CHEMBL1200380
LigandBox: D02764
LinkDB All DBs
KCF data Show

ATOM        17
            1   C8y C    20.2300  -29.1200
            2   C8y C    20.2300  -30.5200
            3   N5x N    21.4424  -31.2200
            4   C8y C    22.6549  -30.5200
            5   N4x N    22.6549  -29.1200 #-
            6   C8y C    21.4424  -28.4200
            7   N1a N    23.8860  -31.2310
            8   O5x O    21.4424  -27.0202
            9   N5x N    18.8985  -28.6874
            10  C8x C    18.0756  -29.8200
            11  N4y N    18.8985  -30.9526
            12  C1b C    18.8985  -32.3526
            13  O2a O    17.6927  -33.0488
            14  C1b C    16.4896  -32.3540
            15  C1b C    15.3060  -33.0372
            16  O1a O    14.1129  -32.3481
            17  Z   Na   24.4300  -29.1200 #+
BOND        17
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     6   8 2
            9     1   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1

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