KEGG   DRUG: Interferon gamma-1a
Entry
D03357                      Drug                                   
Name
Interferon gamma-1a (genetical recombination) (JAN);
Interferon gamma-1a;
Biogamma (TN)
Formula
C761H1206N214O225S6
Exact mass
17134.7830
Mol weight
17145.42
Class
Immunological agent
 DG01752  Interferone
Remark
Therapeutic category: 6399
ATC code: L03AB03
Chemical structure group: DG00737
Product (DG00737): D00747<US> D03357<JP>
Efficacy
Antineoplastic, Immunomodulator, Biological response modifier
Target
IFNGR1 (CD119) [HSA:3459] [KO:K05132]
IFNGR2 [HSA:3460] [KO:K05133]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa05200  Pathways in cancer
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB03 Interferon gamma
      D03357  Interferon gamma-1a (genetical recombination) (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   639  Miscellaneous
    6399  Others
     D03357  Interferon gamma-1a (genetical recombination) (JAN)
Drug groups [BR:br08330]
 Immunological agent
  DG01752  Interferone
   DG00737  Interferon gamma
    D03357  Interferon gamma-1a
Drug classes [BR:br08332]
 Immunological agent
  DG01752  Interferone
   D03357  Interferon gamma-1a
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interferon receptors
    IFNGR1 (CD119)
     D03357  Interferon gamma-1a (genetical recombination) (JAN) <JP>
    IFNGR2
     D03357  Interferon gamma-1a (genetical recombination) (JAN) <JP>
Drug groups [BR:br08330]
 Immunological agent
  DG01752  Interferone
   DG00737  Interferon gamma
Other DBs
CAS: 98059-18-8
PubChem: 17397506
LinkDB

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