KEGG   DRUG: PhentermineHelp
Entry
D05458                      Drug                                   

Name
Phentermine (USAN/INN)
Product
  Generic
Formula
C10H15N
Exact mass
149.1204
Mol weight
149.2328
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01706  Antiobesity
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
Remark
Same as: C07438
ATC code: A08AA01
Chemical structure group: DG00102
Product (DG00102): D05458<US> D05459<US>
Efficacy
Appetite suppressant
Comment
Component of Ionamin (TN)
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
MAO [HSA:4128 4129] [KO:K00274]
  Pathway
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
   A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
    A08AA Centrally acting antiobesity products
     A08AA01 Phentermine
      D05458  Phentermine (USAN/INN) <US>
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D05458  Phentermine (USAN/INN) <US>
    SLC6A3 (DAT1)
     D05458  Phentermine (USAN/INN) <US>
    SLC6A4 (HTT)
     D05458  Phentermine (USAN/INN) <US>
 Enzymes
  Oxidoreductases (EC1)
   Amine oxidases
    MAO
     D05458  Phentermine (USAN/INN) <US>
BRITE hierarchy
Other DBs
CAS: 122-09-8
PubChem: 47207127
ChEBI: 8080
ChEMBL: CHEMBL1574
DrugBank: DB00191
LigandBox: D05458
NIKKAJI: J5.348A
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    18.0600  -15.8900
            2   C1b C    19.2500  -15.1900
            3   C8x C    18.0600  -17.2900
            4   C8x C    16.8700  -15.1900
            5   C1d C    20.4400  -15.8900
            6   C8x C    16.8700  -17.9900
            7   C8x C    15.6800  -15.8900
            8   C1a C    20.4400  -14.3500
            9   C1a C    20.4400  -17.2900
            10  N1a N    21.6300  -15.1900
            11  C8x C    15.6800  -17.2900
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     4   7 2
            7     5   8 1
            8     5   9 1
            9     5  10 1
            10    6  11 2
            11    7  11 1

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