KEGG   DRUG: StiripentolHelp
Entry
D05928                      Drug                                   

Name
Stiripentol (JAN/USAN/INN)
Product
Formula
C14H18O3
Exact mass
234.1256
Mol weight
234.2909
Structure
Mol fileKCF fileDB search
Class
Enzyme substrate
 DG01892  CYP1A2 substrate
 DG01639  CYP2C19 substrate
 DG01633  CYP3A substrate
Enzyme inhibitor
 DG01634  CYP1A2 inhibitor
 DG01643  CYP2C9 inhibitor
 DG01933  CYP2C19 inhibitor
 DG01645  CYP2D6 inhibitor
 DG02852  CYP3A inhibitor
  DG01522  CYP3A4 inhibitor
 DG01522  CYP3A4 inhibitor
Remark
Therapeutic category: 1139
ATC code: N03AX17
Product: D05928<JP/US>
Efficacy
Anticonvulsant, Antiepileptic
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP2C19 [HSA:1557], CYP3A4 [HSA:1576]
Interaction
CYP inhibition: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576], CYP2D6 [HSA:1565], CYP2C19 [HSA:1557], CYP2C9 [HSA:1559]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX17 Stiripentol
      D05928  Stiripentol (JAN/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1139  Others
     D05928  Stiripentol (JAN/USAN/INN)
Drug classes of therapeutic agents [br08360.html]
 Neurological agents
  D05928
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D05928
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D05928
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D05928
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D05928
BRITE hierarchy
Other DBs
CAS: 137767-55-6 49763-96-4
PubChem: 47207586
ChEMBL: CHEMBL1983350
LigandBox: D05928
NIKKAJI: J10.374H
LinkDB All DBs
KCF data Show

ATOM        17
            1   C8y C    16.0300  -17.9200
            2   C8y C    16.0300  -19.3200
            3   C8x C    17.2424  -20.0200
            4   C8x C    18.4549  -19.3200
            5   C8y C    18.4549  -17.9200
            6   C8x C    17.2424  -17.2200
            7   O2x O    14.6985  -17.4874
            8   C1x C    13.8756  -18.6200
            9   O2x O    14.6985  -19.7526
            10  C2b C    19.6860  -17.2090
            11  C2b C    20.8912  -17.9047
            12  C1c C    22.0735  -17.2219
            13  C1d C    23.2675  -17.9112
            14  O1a O    22.0735  -15.8202
            15  C1a C    24.4799  -18.6112
            16  C1a C    22.5571  -19.1422
            17  C1a C    23.9565  -16.7172
BOND        18
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     8   9 1
            10    2   9 1
            11    5  10 1
            12   10  11 2
            13   11  12 1
            14   12  13 1
            15   12  14 1
            16   13  15 1
            17   13  16 1
            18   13  17 1

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