| Entry |
|
|---|
| Name |
Cinitapride (INN);
Paxapride (TN) |
|---|
| Formula |
C21H30N4O4
|
|---|
| Exact mass |
402.2267
|
|---|
| Mol weight |
402.49
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
Analgesic
DG01484 5-HT1B-receptor agonist
DG01485 5-HT1D-receptor agonist
DG01518 5-HT1B/1D-receptor agonist
Gastrointestinal agent
DG01763 Propulsive
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-emetic, Serotonin receptor agonist/antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03F PROPULSIVES
A03FA Propulsives
A03FA08 Cinitapride
D07700 Cinitapride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG01520 Cinitapride
D07700 Cinitapride
Analgesic
DG01484 5-HT1B-receptor agonist
DG01520 Cinitapride
D07700 Cinitapride
DG01485 5-HT1D-receptor agonist
DG01520 Cinitapride
D07700 Cinitapride
DG01518 5-HT1B/1D-receptor agonist
DG01520 Cinitapride
D07700 Cinitapride
Gastrointestinal agent
DG01763 Propulsive
DG01520 Cinitapride
D07700 Cinitapride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
DG01520 Cinitapride
D07700 Cinitapride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR1
D07700 Cinitapride (INN)
HTR2
D07700 Cinitapride (INN)
HTR4
D07700 Cinitapride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG01520 Cinitapride
Analgesic
DG01484 5-HT1B-receptor agonist
DG01520 Cinitapride
DG01485 5-HT1D-receptor agonist
DG01520 Cinitapride
DG01518 5-HT1B/1D-receptor agonist
DG01520 Cinitapride
Gastrointestinal agent
DG01763 Propulsive
DG01520 Cinitapride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
DG01520 Cinitapride
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8y C 13.3700 -15.8200
2 C8y C 13.3700 -14.4200
3 C8x C 14.5600 -13.7200
4 C8y C 15.8200 -14.4200
5 C8y C 15.8200 -15.8200
6 C8x C 14.5600 -16.5200
7 N2b N 12.1800 -16.5200 #+
8 N1a N 12.1800 -13.7200
9 O2a O 17.0100 -13.7200
10 C1b C 18.2000 -14.4200
11 C1a C 19.3900 -13.7200
12 C5a C 17.0100 -16.5200
13 N1b N 18.2000 -15.8200
14 C1y C 19.3900 -16.5200
15 C1x C 20.5800 -15.8200
16 C1x C 21.7700 -16.5200
17 N1y N 21.7700 -17.9200
18 C1x C 20.5800 -18.6200
19 C1x C 19.3900 -17.9200
20 C1b C 23.0300 -18.6200
21 C1y C 24.2200 -17.9200
22 C1x C 24.2200 -16.5200
23 C1x C 25.4100 -15.8200
24 C2x C 26.6000 -16.5200
25 C2x C 26.6000 -17.9200
26 C1x C 25.4100 -18.6200
27 O3a O 10.7100 -15.7500 #-
28 O3a O 12.1800 -17.9200
29 O5a O 17.0100 -17.9200
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 2 8 1
9 4 9 1
10 9 10 1
11 10 11 1
12 5 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 14 19 1
21 17 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 23 24 1
26 24 25 2
27 25 26 1
28 21 26 1
29 7 27 1
30 7 28 2
31 12 29 2
|
|---|
