Homo sapiens (human): 3351
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Entry
3351 CDS
T01001
Symbol
HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Name
(RefSeq) 5-hydroxytryptamine receptor 1B
KO
K04153
5-hydroxytryptamine receptor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04024
cAMP signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04726
Serotonergic synapse
hsa04742
Taste transduction
Drug target
Almotriptan (
DG00839
):
D02824
D02825
<US>
Alniditan dihydrochloride:
D02826
Avitriptan fumarate:
D03014
Cinitapride (
DG01520
):
D07700
D07701
Dihydroergotamine (
DG00833
):
D02211
<US>
D07837
D07838
Eletriptan (
DG00840
):
D01973
<JP/US>
D07887
D11617
<US>
Elzasonan (
DG01314
):
D03982
D03983
Ergot alkaloids:
D07906
Ergotamine (
DG00834
):
D00679
<US>
Frovatriptan (
DG00841
):
D04264
<US>
D07997
Indorenate hydrochloride:
D04533
Naratriptan (
DG00837
):
D00674
<JP/US>
D08255
Pizotifen (
DG00842
):
D05523
D08397
Rizatriptan (
DG00838
):
D00675
<JP/US>
D05740
D08485
Sumatriptan (
DG00836
):
D00451
<JP/US>
D00676
<JP/US>
Zolmitriptan:
D00415
<JP/US>
Zotepine:
D01321
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
3351 (HTR1B)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
3351 (HTR1B)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
3351 (HTR1B)
09157 Sensory system
04742 Taste transduction
3351 (HTR1B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
3351 (HTR1B)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Biogenic amine
Serotonin
3351 (HTR1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7TM_GPCR_Srx
7tm_4
Motif
Other DBs
NCBI-GeneID:
3351
NCBI-ProteinID:
NP_000854
OMIM:
182131
HGNC:
5287
Ensembl:
ENSG00000135312
Vega:
OTTHUMG00000015066
Pharos:
P28222
(Tclin)
UniProt:
P28222
A8K215
X5D7I5
Structure
PDB
LinkDB
All DBs
Position
6:complement(77460924..77463491)
Genome browser
AA seq
390 aa
AA seq
DB search
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atggaggaaccgggtgctcagtgcgctccaccgccgcccgcgggctccgagacctgggtt
cctcaagccaacttatcctctgctccctcccaaaactgcagcgccaaggactacatttac
caggactccatctccctaccctggaaagtactgctggttatgctattggcgctcatcacc
ttggccaccacgctctccaatgcctttgtgattgccacagtgtaccggacccggaaactg
cacaccccggctaactacctgatcgcctctctggcggtcaccgacctgcttgtgtccatc
ctggtgatgcccatcagcaccatgtacactgtcaccggccgctggacactgggccaggtg
gtctgtgacttctggctgtcgtcggacatcacttgttgcactgcctccatcctgcacctc
tgtgtcatcgccctggaccgctactgggccatcacggacgccgtggagtactcagctaaa
aggactcccaagagggcggcggtcatgatcgcgctggtgtgggtcttctccatctctatc
tcgctgccgcccttcttctggcgtcaggctaaggccgaagaggaggtgtcggaatgcgtg
gtgaacaccgaccacatcctctacacggtctactccacggtgggtgctttctacttcccc
accctgctcctcatcgccctctatggccgcatctacgtagaagcccgctcccggattttg
aaacagacgcccaacaggaccggcaagcgcttgacccgagcccagctgataaccgactcc
cccgggtccacgtcctcggtcacctctattaactcgcgggttcccgacgtgcccagcgaa
tccggatctcctgtgtatgtgaaccaagtcaaagtgcgagtctccgacgccctgctggaa
aagaagaaactcatggccgctagggagcgcaaagccaccaagaccctagggatcattttg
ggagcctttattgtgtgttggctacccttcttcatcatctccctagtgatgcctatctgc
aaagatgcctgctggttccacctagccatctttgacttcttcacatggctgggctatctc
aactccctcatcaaccccataatctataccatgtccaatgaggactttaaacaagcattc
cataaactgatacgttttaagtgcacaagttga
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