Homo sapiens (human): 3352
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Entry
3352 CDS
T01001
Symbol
HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Name
(RefSeq) 5-hydroxytryptamine receptor 1D
KO
K04153
5-hydroxytryptamine receptor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04024
cAMP signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04082
Neuroactive ligand signaling
hsa04726
Serotonergic synapse
hsa04742
Taste transduction
Network
nt06544
Neuroactive ligand signaling
Element
N01901
Serotonin-HTR1/5-GNAI/O signaling pathway
Drug target
Almotriptan (
DG00839
):
D02824
D02825
<US>
Alniditan dihydrochloride:
D02826
Avitriptan fumarate:
D03014
Cinitapride (
DG01520
):
D07700
D07701
Cyproheptadine (
DG01109
):
D02234
<JP/US>
D07765
Dihydroergotamine (
DG00833
):
D02211
<US>
D07837
D07838
Eletriptan (
DG00840
):
D01973
<JP/US>
D07887
D11617
Elzasonan (
DG01314
):
D03982
D03983
Ergot alkaloids:
D07906
Ergotamine (
DG00834
):
D00679
<US>
Fenfluramine (
DG00103
):
D04148
<JP/US>
D07945
Frovatriptan (
DG00841
):
D04264
<US>
D07997
Indorenate hydrochloride:
D04533
Naratriptan (
DG00837
):
D00674
<JP/US>
D08255
Pizotifen (
DG00842
):
D05523
D08397
Rizatriptan (
DG00838
):
D00675
<JP/US>
D05740
D08485
Sumatriptan (
DG00836
):
D00451
<JP/US>
D00676
<JP/US>
Zolmitriptan:
D00415
<JP/US>
Zotepine:
D01321
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
3352 (HTR1D)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
3352 (HTR1D)
04082 Neuroactive ligand signaling
3352 (HTR1D)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
3352 (HTR1D)
09157 Sensory system
04742 Taste transduction
3352 (HTR1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
3352 (HTR1D)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Biogenic amine
Serotonin
3352 (HTR1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7tm_4
7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID:
3352
NCBI-ProteinID:
NP_000855
OMIM:
182133
HGNC:
5289
Ensembl:
ENSG00000179546
UniProt:
P28221
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(23191895..23217502)
Genome browser
AA seq
377 aa
AA seq
DB search
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtccccactgaaccagtcagcagaaggccttccccaggaggcctccaacagatccctg
aatgccacagaaacctcagaggcttgggatcccaggaccctccaggcgctcaagatctcc
cttgccgtggtcctttccgtcatcacactggccacagtcctctccaatgcctttgtactc
accaccatcttactcaccaggaagctccacacccctgccaactacctgattggctccctg
gccaccaccgacctcttggtttccatcttggtaatgcccatcagcatcgcctataccatc
acccacacctggaactttggccaaatcttgtgtgacatctggctgtcctctgacatcacg
tgctgcacagcctccatcctgcatctctgtgtcattgctctggacaggtactgggcaatc
acagatgccctggaatacagtaaacgcaggacggctggccacgcggccaccatgatcgcc
attgtctgggccatctccatctgcatctccatccccccgctcttctggcggcaggccaag
gcccaggaggagatgtcggactgtctggtgaacacctctcagatctcctacaccatctac
tccacctgtggggccttctacattccctcggtgttgctcatcatcctatatggccggatc
taccgggctgcccggaaccgcatcctgaatccaccctcactctatgggaagcgcttcacc
acggcccacctcatcacaggctctgccgggtcctcgctctgctcgctcaactccagcctc
catgaggggcactcgcactcggctggctcccctctctttttcaaccacgtgaaaatcaag
cttgctgacagtgccctggaacgcaagaggatttctgctgctcgagaaaggaaagccact
aaaatcctgggcatcattctgggggcctttatcatctgctggctgcccttcttcgtggtg
tctctggtcctccccatctgccgggactcctgctggatccacccggcgctctttgacttc
ttcacctggctaggctatttaaactccctcatcaatccaataatctacactgtgtttaat
gaagagtttcggcaagcttttcagaaaattgtccctttccggaaggcctcctag
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