Entry |
|
Name |
Desipramine (INN) |
Formula |
C18H22N2
|
Exact mass |
266.1783
|
Mol weight |
266.38
|
Structure |

|
Simcomp |
|
Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
|
Remark |
Product (DG00927): | D00812<US> |
|
Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
Target |
|
Pathway |
|
Interaction |
|
Structure map |
map07234 | Neurotransmitter transporter inhibitors |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA01 Desipramine
D07791 Desipramine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00927 Desipramine
D07791 Desipramine
DG01728 Tricyclic antidepressant
DG00927 Desipramine
D07791 Desipramine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D07791 Desipramine (INN)
SLC6A4 (HTT)
D07791 Desipramine (INN)
Prodrugs [br08324.html]
D07791
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00927 Desipramine
DG01728 Tricyclic antidepressant
DG00927 Desipramine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 20
1 C1x C 23.0300 -20.4400
2 C8y C 22.1200 -19.3900
3 C8y C 22.4700 -17.9900
4 N1y N 23.7300 -17.4300
5 C1x C 24.4300 -20.5100
6 C8y C 24.9900 -18.0600
7 C8y C 25.2700 -19.3900
8 C8x C 21.4900 -17.0100
9 C8x C 20.1600 -17.4300
10 C8x C 19.8100 -18.7600
11 C8x C 20.7900 -19.7400
12 C8x C 26.6000 -19.8800
13 C8x C 27.6500 -18.9000
14 C8x C 27.3700 -17.5700
15 C8x C 26.0400 -17.0800
16 C1b C 23.7300 -16.0300
17 C1b C 24.9200 -15.3300
18 C1b C 26.1100 -16.0300
19 N1b N 27.3000 -15.4000
20 C1a C 28.5600 -16.1000
BOND 22
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
|