KEGG   DRUG: Telmisartan and amlodipine besilateHelp
Entry
D09743            Mixture   Drug                                   

Name
Telmisartan and amlodipine besilate;
Telmisartan and amlodipine besylate;
Micamlo (TN);
Twynsta (TN)
Product
  Generic
Component
Telmisartan [DR:D00627], Amlodipine besilate [DR:D00615]
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
Remark
Therapeutic category: 2149
ATC code: C09DB04
Product: D09743<JP/US>
Efficacy
Antihypertensive
  Disease
Hypertension [DS:H01633]
Comment
Telmisartan is primarily metabolized by UDP-glucuronosyltransferase (UGT).
Amlodipine is primarily metabolized by CYP3A4.
Metabolism
Enzyme: CYP3A4 [HSA:1576], UGT [KO:K00699]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
    C09DB Angiotensin II receptor blockers (ARBs) and calcium channel blockers
     C09DB04 Telmisartan and amlodipine
      D09743  Telmisartan and amlodipine besilate <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Cardiovascular Agents, Other
   Telmisartan/ Amlodipine
    D09743  Telmisartan and amlodipine besilate
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D09743  Telmisartan and amlodipine besilate
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09743
BRITE hierarchy
Other DBs
PubChem: 124490483
LinkDB All DBs

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