| Entry |
|
|---|
| Name |
Crenolanib besylate (USAN) |
|---|
| Formula |
C26H29N5O2. C6H6O3S
|
|---|
| Exact mass |
601.2359
|
|---|
| Mol weight |
601.72
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Comment |
angiogenesis inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG01361 Crenolanib
D10103 Crenolanib besylate
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
PDGFR family
PDGFR
D10103 Crenolanib besylate (USAN)
FLT3 (CD135)
D10103 Crenolanib besylate (USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG01361 Crenolanib
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 43
1 C8y C 29.9600 -17.6400
2 C8y C 29.9600 -19.0400
3 C8y C 31.1500 -19.7400
4 C8x C 32.4100 -19.0400
5 C8x C 32.4100 -17.6400
6 C8x C 31.1500 -16.9400
7 C8x C 28.7700 -16.9400
8 C8x C 27.5100 -17.6400
9 C8y C 27.5100 -19.0400
10 N5x N 28.7700 -19.7400
11 N1y N 31.1500 -21.1400
12 C1x C 29.9600 -21.8400
13 C1x C 29.9600 -23.2400
14 C1y C 31.1500 -23.9400
15 C1x C 32.4100 -23.2400
16 C1x C 32.4100 -21.8400
17 N1a N 31.1500 -25.3400
18 N4y N 26.3200 -19.7400
19 C8y C 25.0600 -19.1800
20 C8y C 24.0800 -20.2300
21 N5x N 24.7800 -21.4200
22 C8x C 26.1800 -21.1400
23 C8x C 24.5700 -17.8500
24 C8x C 23.2400 -17.5700
25 C8y C 22.3300 -18.6200
26 C8x C 22.7500 -19.9500
27 O2a O 20.9300 -18.3400
28 C1b C 20.0200 -19.3900
29 C1z C 18.6200 -19.3900
30 C1x C 17.6400 -18.3400
31 O2x O 16.6600 -19.3900
32 C1x C 17.6400 -20.3700
33 C1a C 19.1800 -20.6500
34 C8x C 35.1400 -21.5600
35 C8x C 35.1400 -22.9600
36 C8x C 36.3524 -23.6600
37 C8x C 37.5649 -22.9600
38 C8x C 37.5649 -21.5600
39 C8y C 36.3524 -20.8600
40 S4a S 36.3524 -19.4602
41 O1d O 37.7524 -19.4602
42 O1d O 34.9524 -19.4602
43 O1d O 36.3524 -18.0602
BOND 48
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 2 10 1
12 3 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 11 16 1
19 14 17 1
20 9 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 2
25 18 22 1
26 19 23 2
27 23 24 1
28 24 25 2
29 25 26 1
30 20 26 2
31 25 27 1
32 27 28 1
33 28 29 1
34 29 30 1
35 30 31 1
36 31 32 1
37 29 32 1
38 29 33 1
39 34 35 2
40 35 36 1
41 36 37 2
42 37 38 1
43 38 39 2
44 34 39 1
45 39 40 1
46 40 41 2
47 40 42 2
48 40 43 1
|
|---|
