Entry
Name
tyrosinase;
monophenol monooxygenase;
phenolase;
monophenol oxidase;
cresolase;
monophenolase;
tyrosine-dopa oxidase;
monophenol monooxidase;
monophenol dihydroxyphenylalanine:oxygen oxidoreductase;
N-acetyl-6-hydroxytryptophan oxidase;
monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase;
o-diphenol:O2 oxidoreductase;
phenol oxidase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With another compound as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
L-tyrosine,L-dopa:oxygen oxidoreductase
Reaction(IUBMB)
(1) L-tyrosine + O2 = dopaquinone + H2O (overall reaction);
(1a) L-tyrosine + 1/2 O2 = L-dopa [RN:
R00031 ];
(1b) L-dopa + 1/2 O2 = dopaquinone + H2O;
(2) 2 L-dopa + O2 = 2 dopaquinone + 2 H2O [RN:
R00045 ]
Reaction(KEGG)
Substrate
Product
Comment
A type III copper protein found in a broad variety of bacteria, fungi, plants, insects, crustaceans, and mammals, which is involved in the synthesis of betalains and melanin. The enzyme, which is activated upon binding molecular oxygen, can catalyse both a monophenolase reaction cycle (reaction 1) or a diphenolase reaction cycle (reaction 2). During the monophenolase cycle, one of the bound oxygen atoms is transferred to a monophenol (such as L-tyrosine), generating an o-diphenol intermediate, which is subsequently oxidized to an o-quinone and released, along with a water molecule. The enzyme remains in an inactive deoxy state, and is restored to the active oxy state by the binding of a new oxygen molecule. During the diphenolase cycle the enzyme binds an external diphenol molecule (such as L-dopa) and oxidizes it to an o-quinone that is released along with a water molecule, leaving the enzyme in the intermediate met state. The enzyme then binds a second diphenol molecule and repeats the process, ending in a deoxy state [7]. The second reaction is identical to that catalysed by the related enzyme catechol oxidase (EC
1.10.3.1 ). However, the latter can not catalyse the hydroxylation or monooxygenation of monophenols.
History
EC 1.14.18.1 created 1972, modified 1976, modified 1980 (EC 1.14.17.2 created 1972, incorporated 1984), modified 2012
Pathway
ec00950 Isoquinoline alkaloid biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
PBI : 103060005(TYR) 103063605
XLA : 100158309 108704650 108708762 108710021 108719638 108719639 121395206
XTR : 100125152(tyr) 100486242 100492641
NPR : 108792805 108792810 108794763(TYR) 108801245 108803423 108804169
RTEM : 120920386 120920756 120920840 120921028 120921029 120928838 120928968(TYR) 120941784 120941786
BBUF : 120981433 120981998 120981999 120982591 120982592 120982593 120982594 120992318 120994196(TYR) 120996662 120996663 121002078 121002080
BGAR : 122921761 122921791 122921836 122921846 122921943 122921986 122922023 122922217 122923300(TYR) 122931738 122931739 122932707
SRX : 107731812 107737432(tyr)
SANH : 107669900 107670098
CCAR : 109077077 109082593
CAUA : 113058766 113100299 113114712
MASI : 127422597 127429874
IPU : 100304491 108277956(tyr)
IFU : 128620020 128621333(tyr)
PHYP : 113543610 113544601
SMEO : 124393257 124394828(tyr)
TFD : 113637826(tyr) 113659178
TVC : 132857969(tyr) 132863019
TRN : 134332925 134334725(tyr)
AMEX : 103040843(tyr) 103041136
CMAO : 118800559(tyr) 118824597
EEE : 113578741(tyr) 113581657
TRU : 101064772(tyr) 101080145
TFS : 130521098 130535552(tyr) 130537493
TNG : GSTEN00010318G001 GSTEN00018906G001
TBEN : 117470246(tyr) 117490431
CGOB : 115017793(tyr) 115018879
PGEO : 117457806(tyr) 117458840
GACU : 117534898(tyr) 117535274
EMAC : 134871964 134880315(tyr)
ELY : 117253957 117260186(tyr) 117272046
EFO : 125888825(tyr) 125898293 125899546
PLEP : 121943428(tyr) 121943933 121952100
SLUC : 116037037 116048241(tyr)
ECRA : 117942457(tyr) 117954992
ESP : 116687073(tyr) 116700242
PFLV : 114552647(tyr) 114566690
GAT : 120822041 120828666(tyr)
PPUG : 119213809(tyr) 119215419
AFB : 129091276(tyr) 129113883
CLUM : 117741431(tyr) 117742834
PSWI : 130189390 130211087(tyr)
CANA : 137790492(tyr) 137803064
CVE : 137876404 137877541(tyr)
MSAM : 119883400(tyr) 119895337
SCHU : 122878052 122879443(tyr) 122888177
CUD : 121518828 121524120(tyr)
ALAT : 119006367(tyr) 119030940
ASTR : 137596608(tyr) 137606556
ONL : 100700374 100707700(tyr)
OAU : 116322990(tyr) 116331461
OLA : 100049427(tyr) 101171514
OML : 112139508 112150029(tyr)
CSAI : 133441684(tyr) 133459415
XMA : 102216777 102222951(tyr)
XCO : 114153091 114161843(tyr)
XHE : 116708061(tyr) 116728342
PRET : 103474486(tyr) 103475522
PFOR : 103140502 103146266(tyr)
PLAI : 106950591 106958863(tyr)
PMEI : 106914104 106918015(tyr)
GAF : 122833005(tyr) 122844839
PPRL : 129359260(tyr) 129368489
CVG : 107087918 107091929(tyr)
CTUL : 119771817(tyr) 119783464
GMU : 124876592 124884508(tyr)
NFU : 107380455(tyr) 107386962
KMR : 108236980 108244618(tyr)
ALIM : 106514125 106517255(tyr)
NWH : 119411088(tyr) 119420008
AOCE : 111565888 111572659(tyr) 111573059
MCEP : 125014064(tyr) 125021303
CSEM : 103378543(tyr) 103395402
POV : 109634605(tyr) 109635738
SSEN : 122773016(tyr) 122779548
HHIP : 117772813(tyr) 117773990
HSP : 118106457(tyr) 118122668
SMAU : 118299879(tyr) 118301560
LCF : 108886621 108888021 108893275
SDU : 111217124 111220162 111224123(tyr) 111238342
SLAL : 111651624 111655308(tyr) 111664331 111668310
XGL : 120792070(tyr) 120794477 120802701
HCQ : 109509733 109525374(tyr)
SSCV : 125972234(tyr) 125982324
SBIA : 133491776 133504590(tyr)
PEE : 133404965(tyr) 133416504
PTAO : 133467407 133482359(tyr)
BPEC : 110158560 110174305(tyr)
MALB : 109959313 109971605(tyr)
BSPL : 114868616(tyr) 114868934
SJO : 128358013 128360949(tyr) 128371889
SASA : 100136546 106569882 106588324
STRU : 115173621 115176221 115206586
OTW : 112232177 112267296(tyr)
OMY : 100135825 100135828(tyr)
OGO : 124005778(tyr) 124013126 124044371
OKE : 118381912(tyr) 118398111 118399383
SALP : 111955187 112073729
SNH : 120022663 120027332 120028905(tyr)
CCLU : 121567810 121572854 121585699
ELS : 105024066(tyr) 105026640
SFM : 108923732 108932465(tyr)
AANG : 118209325(tyr) 118232067 118235116
ARUT : 117404921 117405438 117406512 117414286 117965811
HOC : 132814808 132814809 132814810 132816707(tyr)
BFO : 118403552 118403555 118403626 118405245 118406129 118406482 118410197 118414777 118417650 118420461 118421210 118432227
BBEL : 109465224 109465439 109465936 109466145 109473472 109476713
CIN : 100179878 100182881 100183064
SKO : 100368593 100368747 100376573 100376875
DME : Dmel_CG42639(PPO1) Dmel_CG42640(PPO3)
DSI : Dsimw501_GD11733(Dsim_GD11733) Dsimw501_GD25430(Dsim_GD25430)
DYA : Dyak_GE10651 Dyak_GE13951 Dyak_GE14257
SCAC : 106088616 106088618
LSQ : 119602309 119602310 119602311
CLON : 129610838 129610839
AGA : 1269042 1275792 1275799 1276915
ACOZ : 120947481 120947482 120947981 120951745
AARA : 120895449 120897988 120897990
AMER : 121592419 121592420 121592421 121593435
ASTE : 118509466 118511824 118511833
AMOU : 128301355 128302199 128304807
AALI : 118464146 118465171
AAG : 5566258 5566259 5574118 5575359 5575366 5578062
AALB : 109408587 109408601 109423853 109423856 109431713 109431716 115260125 115267476 115267500 115267501 115269621 115270199 115270200 115270202
ASUA : 134211140 134211486 134211487 134211488 134215173 134215447
CQU : CpipJ_CPIJ005078 CpipJ_CPIJ005187 CpipJ_CPIJ009877 CpipJ_CPIJ009878 CpipJ_CPIJ016563 CpipJ_CPIJ016564
CPII : 120412910 120413405 120413408 120413414 120413423 120417857
BCOO : 119066132 119075318 119081277 119083655
PJA : 122244459 122244460 122245324 122251425 122256095 122264827 122264830
PCHN : 125031336 125045898 125045899 125046082 125046086 125046091 125046093 125046164 125046223 125046228 125046232 125046233 125046236 125046240 125046244 125046247
HAME : 121862863 121862864 121862865 121862866 121862867 121877318 121877332 121877417 121877419 121877420 121877421 121877422 121879283 121879296 121880036 121880042 121880057 121880137
PCLA : 123746131 123746134 123746135 123760021 123760023 123760024 123760025 123760026 123760027 123763667 123763670 123773414 123773415 123773416 123773417 123773418 123773420 123773421 123773422 123773423
CQD : 128685078 128692748 128692754 128692760 128693499 128694368 128694464 128694465 128694466 128694467 128694468 128694471 128694472 128694473 128694474
PTRU : 123505735 123510903 123510904 123513867 123516769 123516775 123519961 123519962 123519963 123519964 123519966 123519969 123519970
ESN : 126981081 126981089 126981097 126981104 126981111 126981139 126988766 126988767 126988768 126988770 126988771 126988772 126988773 126988774 126988775 127001575 127005376
UDV : 129216085 129231827 129233050
LPOL : 106459573 106466062
CBR : CBG_04025(Cbr-tyr-4)
LOA : LOAG_01721 LOAG_01722
PMAX : 117337450 117338000
LJP : 135462975 135462978 135463034
SMM : Smp_013540 Smp_050270
OVI : T265_06081 T265_07191 T265_08937
EPA : 110236302 110240416 110247811 110249873
ATEN : 116287291 116297103 116298694 116298734 116305009 116305999
ADF : 107334638 107353911 107356803
AMIL : 114967052 114972254
PDAM : 113670632 113677267 113679449 113682212 113682213 113682241 113682242
SPIS : 111323206 111327271 111329757 111332088 111339209 111347611
DGT : 114521715 114523285 114525179 114528374 114528375 114540274
XEN : 124434147 124434150 124434367 124446883 124452199 124456338
HSY : 130639731 130639757 130642685 130642711 130650855
NCR : NCU00776(T) NCU05762 NCU08615 NCU09199 NCU10031 NCU10865 NCU11382
NTE : NEUTE1DRAFT103253(NEUTE1DRAFT_103253) NEUTE1DRAFT117718(NEUTE1DRAFT_117718) NEUTE1DRAFT118745(NEUTE1DRAFT_118745) NEUTE1DRAFT124197(NEUTE1DRAFT_124197) NEUTE1DRAFT125579(NEUTE1DRAFT_125579) NEUTE1DRAFT93419(NEUTE1DRAFT_93419)
SMP : 10802107(SMAC4_09195) 10805042(SMAC4_04920) 10808536(SMAC4_04270) 10808577(SMAC4_04313) 10808704(SMAC4_06010) 10809071(SMAC4_00012) 10810251(SMAC4_01459) 10810296(SMAC4_01505) 10810380(SMAC4_01592)
PAN : PODANS72p219 PODANSg09832 PODANSg10078 PODANSg1860 PODANSg2196 PODANSg2296 PODANSg2513 PODANSg2609 PODANSg315 PODANSg3516 PODANSg4057 PODANSg4293 PODANSg6905 PODANSg7297
PBEL : QC761_105740 QC761_108060 QC761_115850 QC761_118030 QC761_121700 QC761_300460 QC761_300971 QC761_506690 QC761_507480 QC761_510090 QC761_510410 QC761_602370 QC761_603730 QC761_610120 QC761_610400 QC761_700690
PPSD : QC762_0075280 QC762_105740 QC762_108060 QC762_115850 QC762_118030 QC762_121700 QC762_300460 QC762_300971 QC762_506690 QC762_507480 QC762_510090 QC762_510410 QC762_602370 QC762_603730 QC762_610120 QC762_610400 QC762_700690
PPSP : QC763_0039550 QC763_105740 QC763_108060 QC763_115850 QC763_118030 QC763_121700 QC763_300460 QC763_300971 QC763_506690 QC763_507480 QC763_510090 QC763_510410 QC763_602370 QC763_603730 QC763_610120 QC763_610400 QC763_700690
PPSA : QC764_105740 QC764_108060 QC764_115850 QC764_118030 QC764_121700 QC764_300460 QC764_300971 QC764_506690 QC764_507480 QC764_510090 QC764_510410 QC764_602370 QC764_603730 QC764_610120 QC764_610400 QC764_700690
TTT : THITE_124715 THITE_125575 THITE_2037172 THITE_2040058 THITE_2046868 THITE_2056637 THITE_2088815 THITE_2118068 THITE_2131928 THITE_62739
MTM : MYCTH_2029356 MYCTH_2063591 MYCTH_2066939 MYCTH_2117807 MYCTH_2297253 MYCTH_44230 MYCTH_53288 MYCTH_60685 MYCTH_71063 MYCTH_76199
CTHR : CTHT_0006300 CTHT_0018720 CTHT_0047000 CTHT_0054510 CTHT_0072520
MGR : MGG_01571 MGG_02508 MGG_03962 MGG_05862 MGG_05914 MGG_06169 MGG_07419 MGG_07585 MGG_08455 MGG_09614 MGG_10561 MGG_10585 MGG_11274 MGG_11545 MGG_13937 MGG_14157 MGG_14598
PPEI : PpBr36_00685 PpBr36_01090 PpBr36_02328 PpBr36_02591 PpBr36_02685 PpBr36_02731 PpBr36_03009 PpBr36_04432 PpBr36_05465 PpBr36_05572 PpBr36_10017 PpBr36_10043 PpBr36_10084 PpBr36_10675 PpBr36_10726
PGRI : PgNI_00043 PgNI_00061 PgNI_01695 PgNI_02134 PgNI_02259 PgNI_02311 PgNI_02460 PgNI_02818 PgNI_03926 PgNI_05427 PgNI_06966 PgNI_08727 PgNI_11020 PgNI_11047 PgNI_11104 PgNI_12502
TMN : UCRPA7_237 UCRPA7_2909 UCRPA7_3211 UCRPA7_3344 UCRPA7_371 UCRPA7_4229 UCRPA7_5596 UCRPA7_6194 UCRPA7_7423
SSCK : SPSK_03114 SPSK_03125 SPSK_06106 SPSK_06304 SPSK_06317 SPSK_06500
FGR : FGSG_01988 FGSG_03348 FGSG_03531 FGSG_03801 FGSG_04510 FGSG_04869 FGSG_05628 FGSG_08007 FGSG_09522 FGSG_11106 FGSG_11420 FGSG_11450 FGSG_11517 FGSG_11528
FPU : FPSE_02368 FPSE_03294 FPSE_03345 FPSE_03736 FPSE_04043 FPSE_04474 FPSE_04575 FPSE_04679 FPSE_05743 FPSE_06220 FPSE_09325 FPSE_11583 FPSE_12166
FPOA : FPOAC1_000058 FPOAC1_002118 FPOAC1_004095 FPOAC1_005287 FPOAC1_005720 FPOAC1_005917 FPOAC1_006217 FPOAC1_006996 FPOAC1_007384 FPOAC1_007676 FPOAC1_008055 FPOAC1_009825 FPOAC1_012139
FVN : FVRRES_00179 FVRRES_02361 FVRRES_04518 FVRRES_04753 FVRRES_06293 FVRRES_06526 FVRRES_06819 FVRRES_07631 FVRRES_08050 FVRRES_08148 FVRRES_08618 FVRRES_10474 FVRRES_10873 FVRRES_10899 FVRRES_13213 FVRRES_13785
FVR : FVEG_01614 FVEG_03534 FVEG_03589 FVEG_04071 FVEG_06859 FVEG_07441 FVEG_07596 FVEG_07657 FVEG_08309 FVEG_09948 FVEG_10660 FVEG_11137 FVEG_11735 FVEG_12404 FVEG_12513 FVEG_12936 FVEG_13776
FOX : FOXG_04315 FOXG_04561 FOXG_05674 FOXG_06218 FOXG_07401 FOXG_09259 FOXG_13704 FOXG_16885 FOXG_16980 FOXG_18401 FOXG_20392
NHE : NECHADRAFT_47204 NECHADRAFT_66755 NECHADRAFT_75769 NECHADRAFT_77359 NECHADRAFT_83487 NECHADRAFT_85924 NECHADRAFT_87703 NECHADRAFT_98192
FFC : NCS54_00192800 NCS54_00297000 NCS54_00358600 NCS54_00637300 NCS54_01027200 NCS54_01252300 NCS54_01412000 NCS54_01437900
FKR : NCS57_00191000 NCS57_00292200 NCS57_00364100 NCS57_00676300 NCS57_01020500 NCS57_01257400 NCS57_01393600 NCS57_01420700 NCS57_01447700
FMU : J7337_003603 J7337_004077 J7337_007845 J7337_007985 J7337_009520 J7337_010136 J7337_010329 J7337_010558 J7337_011983 J7337_012195 J7337_013242 J7337_013697
TRE : TRIREDRAFT_45445 TRIREDRAFT_50793
TRR : M419DRAFT_142431 M419DRAFT_96450
TATV : 25776692(TrAtP1_012215) 25777593(TrAtP1_007661) 25780128(TrAtP1_010231)
TASP : 36609524(TrAFT101_010490) 36612211(TrAFT101_009492) 36615182(TrAFT101_007774) 36616461(TrAFT101_009487)
MAW : 19247028(J3458_000472) 19247267(J3458_022097) 19247976(J3458_005087) 19250027(J3458_015295) 19252269(J3458_021163) 90964211(J3458_021199)
MAJ : MAA_02091 MAA_07723 MAA_08523 MAA_08534 MAA_08673 MAA_09216 MAA_10022 MAA_10530 MAA_10801
MBRN : 26238408(ustQ_0) 26239659(TYR) 26242521(tyr1_1) 26243569(tyr1_2) 26246866(ustQ_1) 26247267(orsC_1) 26247667(orsC_0)
PCHM : VFPPC_00193 VFPPC_12090
CMT : CCM_02058 CCM_07390 CCM_08750 CCM_09562
AMUS : LMH87_003120 LMH87_004738 LMH87_005347 LMH87_009957
PLJ : 28883541(PLICBS_000498) 28892626(PLICBS_006597)
PTKZ : JDV02_004516 JDV02_007774 JDV02_009614 JDV02_010762
VAL : VDBG_01849 VDBG_02571 VDBG_05486 VDBG_07262 VDBG_08159 VDBG_09565 VDBG_10207
VDA : VDAG_03034 VDAG_04798 VDAG_05971 VDAG_07137 VDAG_09765 VDAG_10051 VDAG_10407
CFJ : CFIO01_00121 CFIO01_00408 CFIO01_00576 CFIO01_00750 CFIO01_01072 CFIO01_01415 CFIO01_02736 CFIO01_03356 CFIO01_03581 CFIO01_03721 CFIO01_03730 CFIO01_03763 CFIO01_05091 CFIO01_05143 CFIO01_05264 CFIO01_05576 CFIO01_05578 CFIO01_05880 CFIO01_06632 CFIO01_07362 CFIO01_07616 CFIO01_08986 CFIO01_10726 CFIO01_10964 CFIO01_11228 CFIO01_11905 CFIO01_12464
CLUP : CLUP02_02097 CLUP02_04310 CLUP02_04575 CLUP02_05823 CLUP02_06789 CLUP02_07485 CLUP02_08488 CLUP02_12699 CLUP02_12701 CLUP02_13192 CLUP02_14108 CLUP02_15690 CLUP02_16424 CLUP02_17169 CLUP02_17264 CLUP02_17940
CHIG : CH63R_00879 CH63R_00885 CH63R_01093 CH63R_01806 CH63R_03193 CH63R_03403 CH63R_05148 CH63R_05546 CH63R_05602 CH63R_07020 CH63R_07299 CH63R_07609 CH63R_10826 CH63R_12386 CH63R_13047 CH63R_13626 CH63R_13766 CH63R_14094 CH63R_14356 CH63R_14563
CDET : 87936518(CDEST_00015) 87938025(CDEST_01522) 87938242(CDEST_01739) 87939604(CDEST_03101) 87939610(CDEST_03107) 87939836(CDEST_03333) 87942221(CDEST_05718) 87943905(CDEST_07402) 87944196(CDEST_07693) 87944479(CDEST_07976) 87944521(CDEST_08018) 87944815(CDEST_08312) 87947207(CDEST_10707) 87947348(CDEST_10848) 87947666(CDEST_11166) 87948520(CDEST_12020) 87948574(CDEST_12074) 87949534(CDEST_13034) 87949803(CDEST_13303) 87951267(CDEST_14767)
SAPO : SAPIO_CDS0763 SAPIO_CDS0817 SAPIO_CDS10283 SAPIO_CDS10337 SAPIO_CDS1849 SAPIO_CDS2486 SAPIO_CDS4183 SAPIO_CDS4560 SAPIO_CDS4594 SAPIO_CDS5307 SAPIO_CDS5719 SAPIO_CDS5814 SAPIO_CDS6610 SAPIO_CDS6711
ELA : UCREL1_10730 UCREL1_11048 UCREL1_11569 UCREL1_2086 UCREL1_4052 UCREL1_4692 UCREL1_4892 UCREL1_5309 UCREL1_6142 UCREL1_9156 UCREL1_9820
PFY : PFICI_00306 PFICI_00735 PFICI_00910 PFICI_01304 PFICI_01382 PFICI_01616 PFICI_01627 PFICI_01793 PFICI_02433 PFICI_02434 PFICI_02467 PFICI_02608 PFICI_03069 PFICI_03179 PFICI_03197 PFICI_03209 PFICI_03416 PFICI_03705 PFICI_03761 PFICI_03798 PFICI_04036 PFICI_04774 PFICI_05651 PFICI_05780 PFICI_06059 PFICI_06134 PFICI_06895 PFICI_07585 PFICI_08399 PFICI_09482 PFICI_09806 PFICI_09835 PFICI_10646 PFICI_10811 PFICI_11301 PFICI_11659 PFICI_11715 PFICI_12414 PFICI_12415 PFICI_12515 PFICI_12711 PFICI_13172 PFICI_14066 PFICI_14194 PFICI_14411 PFICI_14680 PFICI_14681 PFICI_14867 PFICI_14984
SSL : SS1G_01576 SS1G_04725 SS1G_13364 SS1G_14461
BFU : BCIN_01g08630 BCIN_02g02120 BCIN_03g00690 BCIN_03g07730 BCIN_06g00420 BCIN_11g02170 BCIN_13g02250 BCIN_14g05570 BCIN_15g03960 BCIN_15g05090 BCIN_16g01460
MBE : MBM_00428 MBM_00926 MBM_01261 MBM_01908 MBM_04238 MBM_05368 MBM_06721 MBM_07856 MBM_08430 MBM_09162 MBM_09776
PSCO : LY89DRAFT_143304 LY89DRAFT_395176 LY89DRAFT_50069 LY89DRAFT_576321 LY89DRAFT_577417 LY89DRAFT_579440 LY89DRAFT_595981 LY89DRAFT_637354 LY89DRAFT_642764 LY89DRAFT_686719 LY89DRAFT_693452 LY89DRAFT_697902 LY89DRAFT_708542 LY89DRAFT_708689 LY89DRAFT_731629 LY89DRAFT_736605 LY89DRAFT_760926 LY89DRAFT_771157
GLZ : GLAREA_01250 GLAREA_02296 GLAREA_02544 GLAREA_04289 GLAREA_04332 GLAREA_05981 GLAREA_06285 GLAREA_07225 GLAREA_07417 GLAREA_07673 GLAREA_09792 GLAREA_09918 GLAREA_10602 GLAREA_11779 GLAREA_12180 GLAREA_12218 GLAREA_12491
ANI : ANIA_00231(ivoB) ANIA_01318 ANIA_02799 ANIA_05311 ANIA_09388
AFM : AFUA_1G17430 AFUA_3G01070 AFUA_4G13780
ACT : ACLA_008160 ACLA_052770 ACLA_059670 ACLA_063650
NFI : NFIA_001930 NFIA_007900 NFIA_045560 NFIA_102590
AOR : AO090001000117 AO090001000383 AO090010000557 AO090012000590 AO090023000424 AO090026000145 AO090038000061 AO090113000032 AO090701000859
ANG : An01g09220 An03g00280 An09g02980 An09g05130 An12g01670 An15g07670
AFV : AFLA_002308 AFLA_005378 AFLA_006159 AFLA_006771 AFLA_008456 AFLA_008724 AFLA_009744 AFLA_012315 AFLA_014040
ALUC : AKAW2_10018A AKAW2_20977A AKAW2_40349S AKAW2_40531A AKAW2_50055A AKAW2_60029S
ACHE : ACHE_21217S ACHE_40106S ACHE_41013A ACHE_50006S
APUU : APUU_10110S APUU_11902A APUU_50273S APUU_70009A APUU_70291A
PCS : N7525_004501 N7525_006341 N7525_009930 N7525_010038
POU : POX_b03313 POX_b03419 POX_f07688
TMF : EYB26_000106 EYB26_005676 EYB26_006536
TRG : TRUGW13939_00681 TRUGW13939_02323 TRUGW13939_06655 TRUGW13939_09856 TRUGW13939_09870 TRUGW13939_10638
CIM : CIMG_07314 CIMG_07583 CIMG_09471
CPW : 9692343(D8B26_006956) 9692851(D8B26_007850) 9693535(D8B26_008230)
URE : UREG_01037 UREG_04223 UREG_04846 UREG_07700 UREG_07862
PBL : PAAG_00580 PAAG_00699 PAAG_01024 PAAG_06439 PAAG_06600 PAAG_08820
PBN : PADG_01055 PADG_01336 PADG_03805 PADG_04135 PADG_04213 PADG_11373
AJE : HCAG_00691 HCAG_03668 HCAG_04262 HCAG_04336 HCAG_05196 HCAG_06499 HCAG_07859
BGH : BDBG_01177 BDBG_01880 BDBG_01962 BDBG_02780 BDBG_03625 BDBG_07330
PNO : SNOG_01119 SNOG_03559 SNOG_04173 SNOG_04287 SNOG_04568 SNOG_06516 SNOG_08483 SNOG_09849 SNOG_12217 SNOG_12540 SNOG_13474 SNOG_13698 SNOG_14370 SNOG_15093
PTE : PTT_00821 PTT_04675 PTT_06952 PTT_07434 PTT_08919 PTT_13389 PTT_13955 PTT_14992 PTT_17698 PTT_18525 PTT_19801
PTRR : 6338404(PtrM4_021610) 6339083(PtrM4_018500) 6339505(PtrM4_021070) 6340539(PtrM4_058880) 6340608(PtrM4_058520) 6341599(PtrM4_069970) 6343058(PtrM4_117720) 6346288(PtrM4_136270) 6347183(PtrM4_033720) 6347581(PtrM4_124720) 6349122(PtrM4_130770) 90957305(PtrM4_124910) 90958249(PtrM4_152690)
BZE : COCCADRAFT_102316 COCCADRAFT_103009 COCCADRAFT_105909 COCCADRAFT_109170 COCCADRAFT_32562 COCCADRAFT_33898 COCCADRAFT_38698 COCCADRAFT_40308 COCCADRAFT_40958 COCCADRAFT_4379 COCCADRAFT_8081 COCCADRAFT_83302 COCCADRAFT_99049
BSC : COCSADRAFT_107681 COCSADRAFT_182139 COCSADRAFT_190822 COCSADRAFT_193604 COCSADRAFT_195337 COCSADRAFT_195395 COCSADRAFT_196077 COCSADRAFT_33785 COCSADRAFT_355670 COCSADRAFT_358132 COCSADRAFT_79172 COCSADRAFT_79558
BOR : COCMIDRAFT_105359 COCMIDRAFT_105593 COCMIDRAFT_27821 COCMIDRAFT_29404 COCMIDRAFT_38149 COCMIDRAFT_38490 COCMIDRAFT_38979 COCMIDRAFT_39888 COCMIDRAFT_81583 COCMIDRAFT_82953 COCMIDRAFT_85451 COCMIDRAFT_98124
AALT : CC77DRAFT_1007936 CC77DRAFT_1012626 CC77DRAFT_1029770 CC77DRAFT_1031012 CC77DRAFT_1032431 CC77DRAFT_1032694 CC77DRAFT_1037436 CC77DRAFT_1040043 CC77DRAFT_1057474 CC77DRAFT_1060154 CC77DRAFT_1062991 CC77DRAFT_108295 CC77DRAFT_1099203 CC77DRAFT_17420 CC77DRAFT_28637 CC77DRAFT_333754 CC77DRAFT_935643 CC77DRAFT_935744 CC77DRAFT_946375 CC77DRAFT_978718 CC77DRAFT_980510 CC77DRAFT_992059
ARAB : EKO05_0000579 EKO05_0000924 EKO05_0001895 EKO05_0003178 EKO05_0004493 EKO05_0005564 EKO05_0005591 EKO05_0005755 EKO05_0007990 EKO05_0009017 EKO05_0009804 EKO05_0010128 EKO05_0010571 EKO05_0010776
ZTR : MYCGRDRAFT_104299(TYR) MYCGRDRAFT_111476 MYCGRDRAFT_11769 MYCGRDRAFT_39869 MYCGRDRAFT_42698 MYCGRDRAFT_43919 MYCGRDRAFT_51282 MYCGRDRAFT_70129 MYCGRDRAFT_75965 MYCGRDRAFT_77890 MYCGRDRAFT_84703 MYCGRDRAFT_86183 MYCGRDRAFT_94308
PFJ : MYCFIDRAFT_110418 MYCFIDRAFT_120322 MYCFIDRAFT_128367 MYCFIDRAFT_137987 MYCFIDRAFT_163142 MYCFIDRAFT_210572 MYCFIDRAFT_211783 MYCFIDRAFT_57308 MYCFIDRAFT_60660 MYCFIDRAFT_61304 MYCFIDRAFT_62451
FFU : CLAFUR5_02372 CLAFUR5_03570 CLAFUR5_07573 CLAFUR5_08075 CLAFUR5_09414 CLAFUR5_10589 CLAFUR5_10659 CLAFUR5_10868 CLAFUR5_12040 CLAFUR5_12946 CLAFUR5_13723 CLAFUR5_14224 CLAFUR5_14545
CBET : CB0940_02220 CB0940_03657 CB0940_03732 CB0940_04199 CB0940_05011 CB0940_05259 CB0940_05543 CB0940_06070 CB0940_06199 CB0940_07852 CB0940_10374 CB0940_10398 CB0940_10441 CB0940_10613
BCOM : BAUCODRAFT_109268 BAUCODRAFT_139295 BAUCODRAFT_29922 BAUCODRAFT_36350 BAUCODRAFT_68232
NPA : UCRNP2_1491 UCRNP2_2531 UCRNP2_2887 UCRNP2_3166 UCRNP2_4253 UCRNP2_5576 UCRNP2_762 UCRNP2_763 UCRNP2_8263 UCRNP2_8733
TML : GSTUM_00004221001 GSTUM_00008539001 GSTUM_00008562001
TVS : TRAVEDRAFT_113592 TRAVEDRAFT_114906 TRAVEDRAFT_19801
DSQ : DICSQDRAFT_102354 DICSQDRAFT_166418 DICSQDRAFT_51081
PCO : PHACADRAFT_259085 PHACADRAFT_262375
SHS : STEHIDRAFT_125229 STEHIDRAFT_134497 STEHIDRAFT_149781 STEHIDRAFT_149909 STEHIDRAFT_167058 STEHIDRAFT_60059 STEHIDRAFT_85636
HIR : HETIRDRAFT_326548 HETIRDRAFT_384428 HETIRDRAFT_456224
PSQ : PUNSTDRAFT_127383 PUNSTDRAFT_74793 PUNSTDRAFT_98486
ADL : AURDEDRAFT_120413 AURDEDRAFT_130706 AURDEDRAFT_158568 AURDEDRAFT_162433 AURDEDRAFT_172710 AURDEDRAFT_179545 AURDEDRAFT_179828 AURDEDRAFT_181360
FME : FOMMEDRAFT_136217 FOMMEDRAFT_92287
GTR : GLOTRDRAFT_92245 GLOTRDRAFT_92246
RSX : RhiXN_01179 RhiXN_01663 RhiXN_02269 RhiXN_02296 RhiXN_02337 RhiXN_05404 RhiXN_05782 RhiXN_06103 RhiXN_07540 RhiXN_07541 RhiXN_07864 RhiXN_09964 RhiXN_09966 RhiXN_09976 RhiXN_10066 RhiXN_10070 RhiXN_10078 RhiXN_11415 RhiXN_11533 RhiXN_11534 RhiXN_12287
LBC : LACBIDRAFT_185727(R3) LACBIDRAFT_252993(R2) LACBIDRAFT_295069(R1)
CCI : CC1G_00591 CC1G_00628 CC1G_00642 CC1G_02471 CC1G_02744 CC1G_02758 CC1G_05029 CC1G_05599 CC1G_05636 CC1G_06016 CC1G_06017 CC1G_08048 CC1G_09596 CC1G_09997 CC1G_10006 CC1G_10470 CC1G_10864 CC1G_14163
ABP : AGABI1DRAFT114468(AGABI1DRAFT_114468) AGABI1DRAFT114491(AGABI1DRAFT_114491) AGABI1DRAFT114493(AGABI1DRAFT_114493) AGABI1DRAFT116717(AGABI1DRAFT_116717) AGABI1DRAFT62737(AGABI1DRAFT_62737) AGABI1DRAFT85838(AGABI1DRAFT_85838)
ABV : AGABI2DRAFT135027(AGABI2DRAFT_135027) AGABI2DRAFT191507(AGABI2DRAFT_191507) AGABI2DRAFT191532(AGABI2DRAFT_191532) AGABI2DRAFT194055(AGABI2DRAFT_194055) AGABI2DRAFT239416(AGABI2DRAFT_239416)
MPR : MPER_00316 MPER_06625 MPER_10173 MPER_11172
MRR : Moror_13743 Moror_14222 Moror_14459 Moror_16390 Moror_2848 Moror_4191 Moror_5289 Moror_5295
MORE : E1B28_003052 E1B28_003053 E1B28_006242 E1B28_008888 E1B28_012975 E1B28_012985 E1B28_013014
SCM : SCHCO_02601704(SCHCODRAFT_02601704)
SLA : SERLADRAFT_417600 SERLADRAFT_435855 SERLADRAFT_462697
WSE : WALSEDRAFT_31846 WALSEDRAFT_33078 WALSEDRAFT_33098 WALSEDRAFT_51377
WIC : J056_000778 J056_004791 J056_004816
SGRA : EX895_003755 EX895_006074
PGR : PGTG_11024 PGTG_13399 PGTG_17780 PGTG_17781 PGTG_21816
PTRC : PtA15_18A124 PtA15_18A155 PtA15_18A379 PtA15_6A106
PSTR : Pst134EA_003354 Pst134EA_026778 Pst134EA_026779 Pst134EA_026780 Pst134EA_026810 Pst134EA_027080 Pst134EA_027082 Pst134EA_031680
MLR : MELLADRAFT_40700 MELLADRAFT_65069 MELLADRAFT_72825 MELLADRAFT_85700 MELLADRAFT_94290 MELLADRAFT_94291
FCY : FRACYDRAFT_234770 FRACYDRAFT_291506(TYR1)
PIF : PITG_05533 PITG_09759 PITG_22861
PSOJ : PHYSODRAFT_254953 PHYSODRAFT_255991 PHYSODRAFT_262769 PHYSODRAFT_301135 PHYSODRAFT_332303 PHYSODRAFT_352822 PHYSODRAFT_393487 PHYSODRAFT_528364
SPAR : SPRG_03900 SPRG_12325 SPRG_12328 SPRG_12341 SPRG_16940 SPRG_21152
EHX : EMIHUDRAFT_435727 EMIHUDRAFT_441312
TAMN : N4264_04995 N4264_25580
PGY : AWU82_08750 AWU82_09940
PZE : HU754_014905 HU754_027935
PMOE : HV782_015130 HV782_015135 HV782_017940
PCUC : PSH97_17540 PSH97_21785
PSHS : JJN09_06960 JJN09_08460
PBAM : NUH87_04440 NUH87_27990
MISZ : MishRS11D_11940 MishRS11D_27280
CVC : BKX93_07055 BKX93_21325
RPU : CDC45_01730 CDC45_07720
RNC : GO999_07285 GO999_14990
RSC : RCFBP_11480 RCFBP_21150
RSL : RPSI07_1536 RPSI07_3072
RSN : RSPO_c01550(mel) RSPO_c03068
RSM : CMR15_11457 CMR15_30607
RSY : RSUY_22190(melC2_1) RSUY_29370(melC2_2)
RSG : JK151_03685 JK151_20570
BOK : DM82_4935(melC2) DM82_5976(melO)
BOC : BG90_4662(melO) BG90_5660(melC2)
BUU : WS70_21370 WS70_24455 WS70_26070
BSAV : WS86_25910 WS86_27555
BUB : BW23_4486(melO) BW23_6019
PTS : CUJ90_03110 CUJ90_05940 CUJ90_19890
NMU : Nmul_A0527 Nmul_A0920 Nmul_A2156
NLC : EBAPG3_007900 EBAPG3_008435 EBAPG3_010310 EBAPG3_013745
NIZ : NNRS527_01554 NNRS527_02554
SMQ : SinmeB_5263 SinmeB_5898
SMX : SM11_pC0105(mepA1) SM11_pC0156(mepA2)
SKM : PZL22_005469 PZL22_005523
RPHA : AMC79_PC00027 AMC79_PC00097(melA)
RHX : AMK02_PC00028 AMK02_PC00105(melA)
RHK : Kim5_PA00147(melA) Kim5_PD00094
RRG : J3P73_31490 J3P73_34700
BJU : BJ6T_51930 BJ6T_85090
BJP : RN69_25295 RN69_41115
BRO : BRAD285_3390 BRAD285_7735(melO)
BBAN : J4G43_027030 J4G43_047670
BRN : D1F64_02265 D1F64_12490 D1F64_14240
CMB : CSW64_03300 CSW64_10860
CFH : C1707_03765 C1707_11730 C1707_13170
AGE : AA314_02204 AA314_10041
AVM : JQX13_16805 JQX13_43045
CFUS : CYFUS_005445 CYFUS_008812
SMA : SAVERM_1137(melC2) SAVERM_5362(melC2-2)
SGR : SGR_2447(melC2-2) SGR_527(melC2-1)
SANL : KZO11_24635 KZO11_36075
SCYE : R2B67_01595 R2B67_34505
SCB : SCAB_59241(melC2) SCAB_85681(melC2B)
SDV : BN159_5596(melC2) BN159_7561 BN159_8269(melC2)
SALS : SLNWT_3078 SLNWT_5696
SCI : B446_04405 B446_14305
SGU : SGLAU_02720 SGLAU_12285
STRM : M444_30700 M444_30770
SAMB : SAM23877_2730(melC)
SCZ : ABE83_01635 ABE83_33420
SCX : AS200_14210 AS200_28875 AS200_40770
SRW : TUE45_00932(melC2_1) TUE45_03314(melC2_2)
SLE : sle_45350(sle_45350)
SCLF : BB341_09235 BB341_30130
SGS : AVL59_27390 AVL59_41165
STSI : A4E84_02435 A4E84_14195
SALW : CP975_18870 CP975_34810
SCAD : DN051_25000 DN051_34610
SPHW : NFX46_15090 NFX46_34410
SLS : SLINC_0493 SLINC_3116 SLINC_6310
SPLU : LK06_010265 LK06_030665
SVU : B1H20_22510 B1H20_32960
SPUN : BFF78_26985 BFF78_39110
SALF : SMD44_03252 SMD44_04375
SALJ : SMD11_0232 SMD11_2156 SMD11_4471
SLX : SLAV_04435(melC1) SLAV_04520(melC2) SLAV_32845(melC3) SLAV_35305(melC4)
SNZ : DC008_11895 DC008_31765
SGE : DWG14_05427(melC2_1) DWG14_07892(melC2_2)
SQZ : FQU76_00655 FQU76_22085
SCYA : EJ357_16325 EJ357_44480
SGZ : C0216_13500 C0216_13560
SVN : CP980_03950 CP980_04030
SHAW : CEB94_02905 CEB94_14860
SRK : FGW37_11240 FGW37_22855
SFIC : EIZ62_03330 EIZ62_14475
SGAL : CP966_12785 CP966_30965 CP966_33475
SFY : GFH48_26140 GFH48_37635
SAQU : EJC51_05835 EJC51_18655
SCAV : CVT27_01085 CVT27_31670
SSUB : CP968_03800 CP968_03850
SPHV : F9278_01880 F9278_16050
SCIN : CP977_21875 CP977_30610
STSU : B7R87_21695 B7R87_32880
SCHA : CP983_27830 CP983_40880
SGX : H4W23_25780 H4W23_35650
SCOE : CP976_15760 CP976_40205
SSPB : CP982_17385 CP982_21845
SNF : JYK04_07745(melC2_2) JYK04_07760(melC2_3)
SBRO : GQF42_05870 GQF42_16430 GQF42_17135
STUI : GCM10017668_24010 GCM10017668_66110
SCHF : IPT68_03030 IPT68_13135
SHUN : DWB77_04340(melC2_1) DWB77_06688(melC2_2)
SCYG : S1361_03250(melC1) S1361_14845(melC2)
SFEU : IM697_07615 IM697_25760
SCAL : I6J39_22265 I6J39_32740
SGJ : IAG43_10695 IAG43_20265
STRY : EQG64_01365 EQG64_32940
SDD : D9753_23130 D9753_33120
SACT : DMT42_02855 DMT42_14210
SINE : KI385_00440 KI385_07030
SLF : JEQ17_30225 JEQ17_45085
SDEC : L3078_02250 L3078_16180
SAOV : G3H79_18070 G3H79_23065
SYAN : NRK68_31935 NRK68_31995
SAKB : K1J60_28645 K1J60_43135
STAA : LDH80_06280 LDH80_15255
SCAE : IHE65_29110 IHE65_43145
SCIR : STRCI_000415 STRCI_000925 STRCI_003044
SXT : KPP03845_106703(melC2_1) KPP03845_106718(melC2_2)
SGK : PET44_29135 PET44_29205
SARG : HKX69_22325 HKX69_32110
SJN : RI060_27375 RI060_40870
SOV : QZH56_14015 QZH56_23900
SKG : KJK29_24585 KJK29_37690
SCOA : QU709_27720 QU709_43195
SFP : QUY26_19305 QUY26_24640
STTN : BSL84_31835 BSL84_31905
SINN : ABB07_24575 ABB07_34930
STPB : QR97_13135 QR97_38280
SCAJ : O1G22_27340 O1G22_37875
SRPZ : HEP85_03855 HEP85_15025
SCHE : QRN89_01490 QRN89_31825
KAB : B7C62_01160 B7C62_34100
KAU : B6264_26070 B6264_26805
ABRY : NYE86_23055 NYE86_35225
ACTU : Actkin_04030(melC2)
ASIC : Q0Z83_055090 Q0Z83_090170
GLP : Glo7428_0847 Glo7428_5015
NPU : Npun_R1263 Npun_R2099
NFL : COO91_00787 COO91_08722
RIV : Riv7116_1881 Riv7116_3373 Riv7116_4784
SCYT : SAMD_29630 SAMD_57720 SAMD_63740
SCYS : NIES4073_28710 NIES4073_37790
BSEN : DP114_02280 DP114_18080
BOX : DP113_02240 DP113_18015
TSA : AciPR4_2313 AciPR4_2528
ABAC : LuPra_00956 LuPra_02564(melC2)
KOS : KORDIASMS9_02290(melC2)
TAA : NMY3_00348(griF) NMY3_03193(melC2)
» show all
Taxonomy
Reference
1
Authors
Dawson CR, Tarpley WB.
Title
The copper oxidases.
Journal
In: Sumner JB, Myrback K (eds). The Enzymes. 1st ed. Vol. 2. New York: Academic Press; 1951. p. 454-498.
Reference
Authors
Patil SS, Zucker M.
Title
Potato phenolases. Purification and properties.
Journal
J Biol Chem 240:3938-43 (1965)
Reference
Authors
POMERANTZ SH.
Title
Separation, purification, and properties of two tyrosinases from hamster melanoma.
Journal
J Biol Chem 238:2351-7 (1963)
Reference
4
Authors
Robb DA.
Title
`Tyrosinase.
Journal
In: Lontie R (ed). Copper Proteins and Copper Enzymes. Vol. 2. Boca Raton, FL: CRC Press; 1984. p. 207-240.
Reference
Authors
Sanchez-Ferrer A, Rodriguez-Lopez JN, Garcia-Canovas F, Garcia-Carmona F
Title
Tyrosinase: a comprehensive review of its mechanism.
Journal
Reference
Authors
Steiner U, Schliemann W, Strack D
Title
Assay for tyrosine hydroxylation activity of tyrosinase from betalain-forming plants and cell cultures.
Journal
Reference
Authors
Rolff M, Schottenheim J, Decker H, Tuczek F
Title
Copper-O2 reactivity of tyrosinase models towards external monophenolic substrates: molecular mechanism and comparison with the enzyme.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.14.18.1
LinkDB
All DBs