Entry
Symbol
EXTL1
Name
alpha-1,4-N-acetylglucosaminyltransferase EXTL1 [EC:
2.4.1.224 ]
Pathway
map00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
Module
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone
Reaction
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
K02368 EXTL1; alpha-1,4-N-acetylglucosaminyltransferase EXTL1
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases
K02368 EXTL1; alpha-1,4-N-acetylglucosaminyltransferase EXTL1
Enzymes [BR:ko01000 ]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
K02368 EXTL1; alpha-1,4-N-acetylglucosaminyltransferase EXTL1
Glycosyltransferases [BR:ko01003 ]
Glycan extension
O-Glycan
K02368 EXTL1; alpha-1,4-N-acetylglucosaminyltransferase EXTL1
BRITE hierarchy
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Taxonomy UniProt
Reference
Authors
Kim BT, Kitagawa H, Tamura J, Saito T, Kusche-Gullberg M, Lindahl U, Sugahara K
Title
Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.
Journal
Sequence
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