KEGG   ORTHOLOGY: K04386
Entry
K04386                      KO                                     
Symbol
IL1R1, CD121a
Name
interleukin 1 receptor type I
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04064  NF-kappa B signaling pathway
map04380  Osteoclast differentiation
map04640  Hematopoietic cell lineage
map04659  Th17 cell differentiation
map04750  Inflammatory mediator regulation of TRP channels
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05146  Amoebiasis
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05418  Fluid shear stress and atherosclerosis
Disease
H01492  Systemic sclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
   04064 NF-kappa B signaling pathway
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
   04659 Th17 cell differentiation
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
   05163 Human cytomegalovirus infection
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
   05131 Shigellosis
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
   04090 CD molecules
    K04386  IL1R1, CD121a; interleukin 1 receptor type I
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL1 receptor family
   K04386  IL1R1, CD121a; interleukin 1 receptor type I
CD molecules [BR:ko04090]
 Proteins
  K04386  CD121a, IL1R1; interleukin 1 receptor, type I
Other DBs
GO: 0004909
Genes
HSA: 3554(IL1R1)
PTR: 459460(IL1R1)
PPS: 100972617(IL1R1)
GGO: 101133600(IL1R1)
PON: 100172810(IL1R1)
NLE: 100586658(IL1R1)
MCC: 711726(IL1R1)
MCF: 102146317(IL1R1)
CSAB: 103241149(IL1R1)
CATY: 105583647(IL1R1)
PANU: 101003909(IL1R1)
TGE: 112604908(IL1R1)
RRO: 104680311(IL1R1)
RBB: 108524091(IL1R1)
TFN: 117062283(IL1R1)
PTEH: 111542169(IL1R1)
CJC: 100393945(IL1R1)
SBQ: 101031937(IL1R1)
CSYR: 103260528(IL1R1)
MMUR: 105857833(IL1R1)
LCAT: 123637267(IL1R1)
OGA: 100959140(IL1R1)
MMU: 16177(Il1r1)
MCAL: 110293878(Il1r1)
MPAH: 110321407(Il1r1)
RNO: 25663(Il1r1)
MCOC: 116088348(Il1r1)
CGE: 100758740(Il1r1)
MAUA: 101823176(Il1r1)
PLEU: 114690812(Il1r1)
MORG: 121450585(Il1r1)
AAMP: 119822271(Il1r1)
NGI: 103744180(Il1r1)
HGL: 101711273(Il1r1)
CPOC: 100724206(Il1r1)
CCAN: 109682273(Il1r1)
DORD: 105988260(Il1r1)
DSP: 122121295(Il1r1)
NCAR: 124962993
OCU: 100352905(IL1R1)
OPI: 101519459(IL1R1)
TUP: 102492414(IL1R1)
CFA: 481328(IL1R1)
CLUD: 112669932(IL1R1)
VVP: 112915144(IL1R1)
VLG: 121490366(IL1R1)
AML: 100472991(IL1R1)
UMR: 103670641(IL1R1)
UAH: 113247336(IL1R1)
UAR: 123775960(IL1R1)
ELK: 111155931
LLV: 125108912
MPUF: 101670524(IL1R1)
ORO: 101381751(IL1R1)
EJU: 114209829(IL1R1)
ZCA: 113938587(IL1R1)
MLX: 118008270(IL1R1)
FCA: 101080705(IL1R1)
PYU: 121016438(IL1R1)
PBG: 122496688(IL1R1)
PTG: 102958342(IL1R1)
PPAD: 109254564(IL1R1)
AJU: 106968747(IL1R1)
HHV: 120245902(IL1R1)
BTA: 515640(IL1R1)
BOM: 102271047(IL1R1)
BIU: 109565502(IL1R1)
BBUB: 102402346(IL1R1)
CHX: 102187231(IL1R1)
OAS: 101103054(IL1R1)
ODA: 120883612(IL1R1)
CCAD: 122441438(IL1R1)
SSC: 100626904(IL1R1)
CFR: 102503597(IL1R1)
CBAI: 105072217(IL1R1)
CDK: 105099109(IL1R1)
VPC: 102544667(IL1R1)
BACU: 102998234(IL1R1)
LVE: 103084028
OOR: 101277609(IL1R1)
DLE: 111187389(IL1R1)
PCAD: 102973768(IL1R1)
PSIU: 116763886(IL1R1)
ECB: 100009699(IL1R1)
EPZ: 103563183(IL1R1)
EAI: 106839400(IL1R1)
MYB: 102238676(IL1R1)
MYD: 102775132(IL1R1)
MMYO: 118679042(IL1R1)
MLF: 102437031
MNA: 107532712(IL1R1)
PKL: 118727943(IL1R1)
HAI: 109395478(IL1R1)
DRO: 112315147(IL1R1)
SHON: 118994653(IL1R1)
AJM: 119047918(IL1R1) 119047921
PDIC: 114499425(IL1R1)
PHAS: 123811594(IL1R1)
MMF: 118631025(IL1R1)
RFQ: 117033297(IL1R1)
PALE: 102884439(IL1R1)
PGIG: 120584449(IL1R1)
PVP: 105298727(IL1R1)
RAY: 107498102(IL1R1)
MJV: 108404707(IL1R1)
TOD: 119259279(IL1R1)
SARA: 101537237(IL1R1)
LAV: 100657834(IL1R1)
TMU: 101358013
DNM: 101447218(IL1R1)
MDO: 100017751(IL1R1)
GAS: 123241763(IL1R1)
SHR: 100913514
PCW: 110209396(IL1R1)
OAA: 100084073(IL1R1)
GGA: 396481(IL1R1)
PCOC: 116236528
MGP: 100540676
CJO: 107306834
NMEL: 110406790
APLA: 101794055 101795572(IL1RL1)
ACYG: 106041672
AFUL: 116492687
TGU: 100220817(IL1R1)
LSR: 110474740
SCAN: 103812363
PMOA: 120504582
OTC: 121343206
PRUF: 121354092
GFR: 102040488(IL1R1)
FAB: 101815105(IL1R1)
PHI: 102106217(IL1R1)
PMAJ: 107210317
CCAE: 111942272
CCW: 104686063(IL1R1)
CBRC: 103617523(IL1R1)
ETL: 114068702
ZAB: 102065213(IL1R1)
FPG: 101912007
FCH: 102060155
CLV: 102097520(IL1R1)
EGZ: 104126373(IL1RL1) 104126375
NNI: 104019340
PLET: 104626063
PCRI: 104025350(IL1R1)
ACUN: 113484904(IL1R1)
TALA: 104356295
PADL: 103918827 103918873(IL1RL1)
ACHC: 115334517(IL1R1)
HALD: 104322108
CCRI: 104168439
CSTI: 104564189
CMAC: 104473405
FGA: 104080987(IL1RL2)
GSTE: 104250733(IL1RL2)
LDI: 104349371
OHA: 104329456
AAM: 106494064(IL1R1)
AROW: 112966181
NPD: 112954964
DNE: 112984961
ASN: 102377912
AMJ: 102558564(IL1R1)
GGN: 109303109 109303181(IL1RL2)
PSS: 102463929
CMY: 102937532
CPIC: 101942308
CABI: 116832859(IL1R1) 116832861
ACS: 100553004
PVT: 110090152
PBI: 112542425
PMUR: 107288201
PMUA: 114596401(IL1R1)
ZVI: 118084996
GJA: 107110211
XTR: 100491546(il1r1)
RTEM: 120926475(IL1R1)
BGAR: 122931522 122931549(IL1R1)
DRE: 799204(zmp:0000000936) 799279
PPRM: 120479173(zmp:0000000936) 120479174
SMEO: 124377808 124382274 124383179(zmp:0000000936)
TFD: 113646269 113646273(zmp:0000000936) 113648674
LCO: 104928679
CGOB: 115026861
ELY: 117251338
EFO: 125899698
PLEP: 121949002
SLUC: 116063738
ECRA: 117952382
PFLV: 114563795
GAT: 120833889
PPUG: 119229350
MSAM: 119904455
CUD: 121522535
ALAT: 119025790
MZE: 101470103
ONL: 100702660
OAU: 116314797
OLA: 101157257
OML: 112155212
XMA: 102235704
XCO: 114148728
XHE: 116723605
PFOR: 103134846
PLAI: 106936431
PMEI: 106926663
GAF: 122839835
CVG: 107087363
CTUL: 119795929
GMU: 124871075
NFU: 107389426
NWH: 119419396
AOCE: 111563964
MCEP: 125018280
CSEM: 103391984
SSEN: 122763674
HHIP: 117755312
HSP: 118119887
XGL: 120801566
HCQ: 109522385
BPEC: 110169112
MALB: 109968094
BSPL: 114847513
OTW: 112231472 112234773 112239331 112239342(zmp:0000000936)
OMY: 100136037(il-1r1) 110502091 110520326(zmp:0000000936)
OGO: 124044040
ONE: 115111503
SNH: 120057936
CCLU: 121536314
AANG: 118224403
ARUT: 117405220
CMK: 103172493
HAME: 121875633
 » show all
Reference
PMID:2532321
  Authors
Chua AO, Gubler U
  Title
Sequence of the cDNA for the human fibroblast type interleukin-1 receptor.
  Journal
Nucleic Acids Res 17:10114 (1989)
DOI:10.1093/nar/17.23.10114
  Sequence
[hsa:3554]
Reference
  Authors
Slack JL, Schooley K, Bonnert TP, Mitcham JL, Qwarnstrom EE, Sims JE, Dower SK
  Title
Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways.
  Journal
J Biol Chem 275:4670-8 (2000)
DOI:10.1074/jbc.275.7.4670
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