KEGG ORTHOLOGY: K04434

ORTHOLOGY: K04434

Entry

K04434                      KO

Symbol

MAPK8IP1, JIP1

Name

mitogen-activated protein kinase 8 interacting protein 1

Pathway

map04010

MAPK signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1

Genes

HSA:	9479(MAPK8IP1)

PTR:	451148(MAPK8IP1)

PPS:	100981592(MAPK8IP1) 100985578 117976690

GGO:	101139361(MAPK8IP1)

PON:	100441261 100458702(MAPK8IP1)

PPYG:

129008330(MAPK8IP1)

NLE:	100607516(MAPK8IP1)

HMH:	116476310(MAPK8IP1)

SSYN:

129470176 129484179(MAPK8IP1)

MCC:	714950(MAPK8IP1)

MCF:	102117632(MAPK8IP1)

MTHB:

126935744

MNI:	105471651(MAPK8IP1)

CSAB:

103236686(MAPK8IP1)

CATY:

105592787(MAPK8IP1)

PANU:

101010180(MAPK8IP1)

TGE:	112606978(MAPK8IP1)

MLEU:

105554792(MAPK8IP1)

RRO:	104668428(MAPK8IP1)

RBB:	108519265(MAPK8IP1)

TFN:	117080074(MAPK8IP1)

PTEH:

111544921(MAPK8IP1)

CANG:

105527105(MAPK8IP1)

CJC:	100404808(MAPK8IP1)

SBQ:	101035081(MAPK8IP1)

CIMI:

108304882(MAPK8IP1)

ANAN:

105717318(MAPK8IP1)

CSYR:

103252265(MAPK8IP1)

MMUR:

105885267(MAPK8IP1)

LCAT:

123642639(MAPK8IP1)

PCOQ:

105811092(MAPK8IP1)

OGA:	100953493(MAPK8IP1)

MMU:	19099(Mapk8ip1)

MCAL:

110289269(Mapk8ip1)

MPAH:

110317739(Mapk8ip1)

RNO:	116457(Mapk8ip1)

MCOC:

116090498(Mapk8ip1)

ANU:	117703326(Mapk8ip1)

ASYL:

127685634(Mapk8ip1)

MUN:	110549871(Mapk8ip1)

CGE:	100774647(Mapk8ip1)

MAUA:

101835896(Mapk8ip1)

PROB:

127222217(Mapk8ip1)

PLEU:

114699711(Mapk8ip1)

MORG:

121440531(Mapk8ip1)

MFOT:

126489776

AAMP:

119814580(Mapk8ip1)

NGI:	103735057(Mapk8ip1)

HGL:	101705667(Mapk8ip1)

CPOC:

100725179(Mapk8ip1)

CCAN:

109692011(Mapk8ip1)

DORD:

105996069(Mapk8ip1)

DSP:	122104912(Mapk8ip1)

PLOP:

125361234(Mapk8ip1)

NCAR:

124958394

MMMA:

107158578(Mapk8ip1)

ITI:	101962015(Mapk8ip1)

OCU:

100344706

OPI:	101533171(MAPK8IP1)

TUP:	102490526(MAPK8IP1)

GVR:	103588723(MAPK8IP1)

CFA:	483640(MAPK8IP1)

CLUD:

112663278(MAPK8IP1)

VVP:	112923990(MAPK8IP1)

VLG:	121471302(MAPK8IP1)

NPO:	129499237(MAPK8IP1)

AML:	100473891(MAPK8IP1)

UMR:	103672396(MAPK8IP1)

UAH:	113264997(MAPK8IP1)

UAR:	123799584(MAPK8IP1)

ELK:

111149582

LLV:

125078346

MPUF:

101682927(MAPK8IP1)

MNP:	132008220 132008409

MLK:	131811785(MAPK8IP1)

NVS:	122912872(MAPK8IP1)

ORO:	101362732(MAPK8IP1)

EJU:	114215285(MAPK8IP1)

ZCA:	113913798(MAPK8IP1)

MLX:	118015800(MAPK8IP1)

NSU:	110576067(MAPK8IP1)

LWW:	102746249(MAPK8IP1)

FCA:	101085070(MAPK8IP1)

PYU:	121043484(MAPK8IP1)

PCOO:

112865069(MAPK8IP1)

PBG:	122483747(MAPK8IP1)

PVIV:

125176469(MAPK8IP1)

LRUF:

124506025

LGF:	123602255(MAPK8IP1)

AJU:

106978073

PTG:	102949001(MAPK8IP1)

PPAD:

109245088(MAPK8IP1)

PUC:

125934292

PLEZ:

122199169(MAPK8IP1)

HHV:	120228468(MAPK8IP1)

BTA:	524806(MAPK8IP1)

BOM:	102271586(MAPK8IP1)

BIU:	109569050(MAPK8IP1)

BBUB:

102396599(MAPK8IP1)

BBIS:

104990384(MAPK8IP1)

CHX:	102180333(MAPK8IP1)

OAS:	101116934(MAPK8IP1)

BTAX:

128060730(MAPK8IP1)

CSUM:

138093149(MAPK8IP1)

ODA:	120876927(MAPK8IP1)

CCAD:

122449456(MAPK8IP1)

MREE:

136174923(MAPK8IP1)

OVR:	110122641(MAPK8IP1)

MBEZ:

129554787(MAPK8IP1)

SSC:	100517574(MAPK8IP1)

CFR:	102517128(MAPK8IP1)

CBAI:

105076475(MAPK8IP1)

CDK:	105106850(MAPK8IP1)

VPC:

102529333

BACU:

103016156(MAPK8IP1)

BMUS:

118900172(MAPK8IP1)

LVE:	103088460(MAPK8IP1)

OOR:	101283707(MAPK8IP1)

LALB:

132525828(MAPK8IP1)

DLE:	111183989(MAPK8IP1)

PCAD:

102984082(MAPK8IP1)

PSIU:

116758383(MAPK8IP1)

NASI:

112402032(MAPK8IP1)

ECB:	100056764(MAPK8IP1)

EPZ:	103566871(MAPK8IP1)

EAI:	106843928(MAPK8IP1)

MYB:	102242764(MAPK8IP1)

MYD:	102767242(MAPK8IP1)

MMYO:

118665094(MAPK8IP1)

MLF:	102435955(MAPK8IP1)

MDT:	132241226(MAPK8IP1)

MYUM:

139018896(MAPK8IP1)

PKL:	118712565(MAPK8IP1)

EFUS:

103290852(MAPK8IP1)

MNA:	107530272(MAPK8IP1)

DRO:	112303417(MAPK8IP1)

SHON:

118974489(MAPK8IP1)

AJM:	119064450(MAPK8IP1)

PDIC:

114499926(MAPK8IP1)

PHAS:

123810182(MAPK8IP1)

MMF:	118627949(MAPK8IP1)

PPAM:

129081518(MAPK8IP1)

HAI:	109390177(MAPK8IP1)

RFQ:	117030033(MAPK8IP1)

PALE:

102895072(MAPK8IP1)

PGIG:

120606586(MAPK8IP1)

PVP:	105290007(MAPK8IP1)

RAY:	107511871(MAPK8IP1)

MJV:	108401280(MAPK8IP1)

TOD:	119255326(MAPK8IP1)

SARA:

101553728(MAPK8IP1)

SFUM:

130039902(MAPK8IP1)

SETR:

126017610(MAPK8IP1)

LAV:	100668077(MAPK8IP1)

TMU:

101342886

ETF:	101657014(MAPK8IP1)

DNM:

101445307

MDO:	100014835(MAPK8IP1)

GAS:	123255585(MAPK8IP1)

AFZ:

127540050

PCW:	110223934(MAPK8IP1)

TVP:	118852674(MAPK8IP1)

PBRV:

138163870(MAPK8IP1)

OAA:	100681402(MAPK8IP1)

TACU:

119943775(MAPK8IP1)

GGA:	423202(MAPK8IP1)

PCOC:

116229179(MAPK8IP1)

MGP:	100539705(MAPK8IP1)

CJO:	107314766(MAPK8IP1)

TPAI:

128085705(MAPK8IP1)

LMUT:

125695467(MAPK8IP1)

NMEL:

110401080(MAPK8IP1)

APLA:

101797637(MAPK8IP1)

ACYG:

106040797(MAPK8IP1)

CATA:

118244338(MAPK8IP1)

AFUL:

116489982(MAPK8IP1)

TGU:	100223904(MAPK8IP1)

LSR:	110472084(MAPK8IP1)

SCAN:

103826673(MAPK8IP1)

PMOA:

120500402(MAPK8IP1)

OTC:	121331672(MAPK8IP1)

PRUF:

121349528(MAPK8IP1)

ATRC:

139590169(MAPK8IP1)

GFR:	102031934(MAPK8IP1)

FAB:	101807504(MAPK8IP1)

OMA:	130254479(MAPK8IP1)

PHI:	102101771(MAPK8IP1)

PMAJ:

107206189(MAPK8IP1)

CCAE:

111930189(MAPK8IP1)

CCW:	104688152(MAPK8IP1)

CBRC:

103620930(MAPK8IP1)

ACOE:

138111469(MAPK8IP1)

ETL:	114059213(MAPK8IP1)

ZAB:	102063353(MAPK8IP1)

ZLE:	135448278(MAPK8IP1)

ACHL:

103800454(MAPK8IP1)

SVG:	106856539(MAPK8IP1)

MMEA:

130573112(MAPK8IP1)

HRT:	120754004(MAPK8IP1)

SATI:

136362539(MAPK8IP1)

CCIC:

134044764(MAPK8IP1)

FPG:	101915910(MAPK8IP1)

FCH:	102057404(MAPK8IP1)

CCRI:

104169545(MAPK8IP1)

NNT:	104402195(MAPK8IP1)

SHAB:

115606197(MAPK8IP1)

ACUN:

113480519(MAPK8IP1)

TALA:

104360878(MAPK8IP1)

ACHC:

115333491(MAPK8IP1)

HLE:	104839678(MAPK8IP1)

AGEN:

126049279

HHAR:

128139540(MAPK8IP1)

GCL:

127016621

LDI:	104353518(MAPK8IP1)

DPUB:

104300582(MAPK8IP1)

PPUS:

135176452(MAPK8IP1)

AVIT:

104273886(MAPK8IP1)

BRHI:

104499122(MAPK8IP1)

EGZ:	104134116(MAPK8IP1)

NNI:	104020460(MAPK8IP1)

PADL:

103921741(MAPK8IP1)

AFOR:

103897542(MAPK8IP1)

CLV:	102095564(MAPK8IP1)

MUI:	104539020(MAPK8IP1)

PGUU:

104463958(MAPK8IP1)

PLET:

104627180(MAPK8IP1)

EHS:	104517100(MAPK8IP1)

CMAC:

104478554(MAPK8IP1)

CUCA:

104067346(MAPK8IP1)

TEO:	104381652(MAPK8IP1)

OHA:	104328154(MAPK8IP1)

ACAR:

104533011

CPEA:

104390460(MAPK8IP1)

CVF:	104295898(MAPK8IP1)

RTD:	128909558(MAPK8IP1)

CRID:

134514401(MAPK8IP1)

AAM:	106498116(MAPK8IP1)

AROW:

112966110(MAPK8IP1)

NPD:	112952898(MAPK8IP1)

TGT:	104573994(MAPK8IP1)

DNE:	112987588(MAPK8IP1)

SCAM:

104150416(MAPK8IP1)

ASN:	102376704(MAPK8IP1)

AMJ:	102575866(MAPK8IP1)

CPOO:

109321294(MAPK8IP1)

GGN:	109298918(MAPK8IP1)

PSS:	102451114(MAPK8IP1)

CMY:	102946734(MAPK8IP1)

CCAY:

125639036(MAPK8IP1)

DCC:	119856953(MAPK8IP1)

CPIC:

101952346(MAPK8IP1)

TST:	117876949(MAPK8IP1)

CABI:

116821711(MAPK8IP1)

MRV:	120403539(MAPK8IP1)

ACS:	100557268(mapk8ip1)

ASAO:

132768298(MAPK8IP1)

PVT:	110081651(MAPK8IP1)

SUND:

121931750(MAPK8IP1)

PBI:	103056157(MAPK8IP1)

PMUR:

107297683(MAPK8IP1)

CTIG:

120315019(MAPK8IP1)

TSR:	106544139(MAPK8IP1)

PGUT:

117665505(MAPK8IP1)

APRI:

131187448(MAPK8IP1)

PTEX:

113438415(MAPK8IP1)

NSS:	113414387(MAPK8IP1)

VKO:	123026265(MAPK8IP1)

PMUA:

114596120(MAPK8IP1)

PRAF:

128413299(MAPK8IP1)

ZVI:	118085249(MAPK8IP1)

HCG:	128337342(MAPK8IP1)

GJA:	107107537(MAPK8IP1)

STOW:

125425941(MAPK8IP1)

EMC:	129324988(MAPK8IP1)

XLA:	108713772 108714940

XTR:	100496373(mapk8ip1)

NPR:	108785459(MAPK8IP1)

RTEM:

120917118(MAPK8IP1)

BBUF:

120980203(MAPK8IP1)

BGAR:

122920578(MAPK8IP1)

PWL:	138283710(MAPK8IP1)

MUO:	115468819(MAPK8IP1)

GSH:	117352402(MAPK8IP1)

DRE:	100333948(mapk8ip1b) 100537717(mapk8ip1a)

SRX:	107707405 107714081 107726184 107745293

SANH:

107654170 107674947 107675386 107683269 107691856

SGH:	107566132 107572995 107589201(mapk8ip1)

CCAR:

109046854 109050576 109065551 109066088

CAUA:

113051733(mapk8ip1) 113072565 113097560

CGIB:

127947037 128014768 128016423

PTET:

122348947(mapk8ip1b) 122357545

LROH:

127156877(mapk8ip1a) 127168419(mapk8ip1b)

OMC:	131534954(mapk8ip1a) 131544133(mapk8ip1b)

PPRM:

120460344(mapk8ip1a) 120477785(mapk8ip1b)

RKG:	130082293(mapk8ip1b) 130085227(mapk8ip1a)

MAMB:

125247612(mapk8ip1a) 125265742(mapk8ip1b)

CIDE:

127507600 127515857

CERY:

137015073(mapk8ip1a) 137030021(mapk8ip1b)

MASI:

127415760 127436217 127437800 127446926

TROS:

130552098(mapk8ip1a) 130553897(mapk8ip1b)

TDW:	130413864(mapk8ip1a) 130428878(mapk8ip1b)

MANU:

129434349(mapk8ip1a) 129453440(mapk8ip1b)

PDAB:

135743954(mapk8ip1b) 135758880 135781270

IPU:	108268451(mapk8ip1a) 108271162(mapk8ip1b)

IFU:	128611625(mapk8ip1a) 128614165(mapk8ip1b)

PHYP:

113523944(mapk8ip1) 113546485

SMEO:

124385561(mapk8ip1a) 124391401(mapk8ip1b)

TFD:	113635657(mapk8ip1a) 113646202(mapk8ip1b)

TVC:	132850579(mapk8ip1b) 132856356(mapk8ip1a)

CGAR:

128532299(mapk8ip1a) 128543468(mapk8ip1b)

NGRA:

132890251(mapk8ip1a) 132899065(mapk8ip1b)

TRN:	134319133(mapk8ip1a) 134331956(mapk8ip1b)

AMEX:

103034521(mapk8ip1b) 103044273(mapk8ip1a)

CMAO:

118806602(mapk8ip1a) 118819420(mapk8ip1b)

EEE:	113581790 113586062(mapk8ip1)

CHAR:

105895585(mapk8ip1a) 105902976(mapk8ip1b)

SPIL:

134094675(mapk8ip1a) 134096247(mapk8ip1b)

TRU:	101061599 101068706(mapk8ip1) 115248386

TFS:	130514023 130536621

TNG:	GSTEN00008510G001 GSTEN00018222G001

LCO:	104925844(mapk8ip1) 104936426

NCC:

104949910

TBEN:

117471209 117484444

CGOB:

115006162(mapk8ip1) 115009114

PGEO:

117443940

GACU:

117549405 117553250

EMAC:

134863889 134881735

ELY:	117259037(mapk8ip1b) 117262338(mapk8ip1a)

EFO:	125879641(mapk8ip1b) 125887866(mapk8ip1a)

PLEP:

121946251(mapk8ip1b) 121950447

SLUC:

116048652 116057299

ECRA:

117945896(mapk8ip1b) 117948612(mapk8ip1a)

ESP:	116693948 116694034

PFLV:

114554444(mapk8ip1) 114559678

GAT:	120808751 120812461 120834473

PPUG:

119195796 119228882

AFB:	129107446 129108788

CLUM:

117728785(mapk8ip1b) 117731704

PSWI:

130192530 130195959

CANA:

137782527 137804673

CVE:	137881392 137882173

MSAM:

119890605 119890838(mapk8ip1b) 119893932

SCHU:

122874471 122877246(mapk8ip1b)

CUD:	121510162(mapk8ip1b) 121515680(mapk8ip1a)

SPUL:

138586163(mapk8ip1b) 138612923(mapk8ip1a)

LMIX:

132973119(mapk8ip1a) 132992474(mapk8ip1b)

ALAT:

119018128(mapk8ip1b) 119024785

ASTR:

137593373 137594599 137594959(mapk8ip1b)

MZE:	101473047(mapk8ip1) 101485749

ONL:	100690324 100698957(mapk8ip1)

OAU:	116321469 116329469(mapk8ip1b)

OLA:	101159567(mapk8ip1) 105354262

OML:	112151874(mapk8ip1a) 112161147(mapk8ip1b)

CSAI:

133444406(mapk8ip1a) 133458044(mapk8ip1b)

XMA:	102235014 102236541(mapk8ip1)

XCO:	114136232 114143332(mapk8ip1)

XHE:	116711403 116718493(mapk8ip1)

PRET:

103462900(mapk8ip1) 103466761

PFOR:

103144193(mapk8ip1)

PLAI:

106953115(mapk8ip1)

PMEI:

106907882 106927365(mapk8ip1)

GAF:	122819202 122836143

PPRL:

129360877 129364141

CVG:	107090417 107094058(mapk8ip1)

CTUL:

119793443 119796332

GMU:	124855152 124867257

NFU:	107381812(mapk8ip1) 107389136

KMR:

108234805

ALIM:

106519098(mapk8ip1) 106533742

NWH:	119415465 119424494

AOCE:

111574909(mapk8ip1b) 111587545(mapk8ip1a)

EJA:	138192529 138208014(mapk8ip1b)

BFRE:

138624867(mapk8ip1b) 138636377

MCEP:

125005464 125014605

CSEM:

103378791(mapk8ip1) 103379622

POV:	109637303(mapk8ip1) 109642436

SSEN:

122772332(mapk8ip1b) 122775372

SSOE:

131459955(mapk8ip1b) 131469763(mapk8ip1a)

HHIP:

117757424(mapk8ip1b) 117762729

HSP:	118109052(mapk8ip1a) 118112083(mapk8ip1b)

PPLT:

128443888 128454316(mapk8ip1b)

SMAU:

118302526(mapk8ip1b) 118315766(mapk8ip1a)

LCF:	108887789(si:ch211-210p4.6) 108902270

SDU:	111222978(mapk8ip1) 111229840

SLAL:

111647707 111654324(mapk8ip1)

XGL:	120793474 120795826(mapk8ip1b)

HCQ:	109519736(mapk8ip1) 109520759

SSCV:

125966680(mapk8ip1b) 125971188(mapk8ip1a)

SBIA:

133498390 133502289

PEE:	133399109 133402667

PTAO:

133472066 133478265

BPEC:

110169044(mapk8ip1) 110169487

ENY:	140349375 140381221(mapk8ip1b)

MALB:

109952770 109965074(mapk8ip1)

BSPL:

114852376(mapk8ip1b) 114857371(mapk8ip1a)

SJO:	128358283(mapk8ip1b) 128359023

SSCO:

133981894 133995904(mapk8ip1b)

GMH:	115550794 115559115

SASA:

106561607 106561900 106573101 106587053

STRU:

115152348 115167623 115197590 115203864

OTW:	112248953 112252669(mapk8ip1a) 112264159

OMY:	110502383 110524536(mapk8ip1a) 110526148(mapk8ip1b)

OGO:	124004042(mapk8ip1a) 124032970 124033315 124034876

ONE:	115112509(mapk8ip1) 115115582

OKI:	109867776 109874202 109888916 109894846

OKE:	118394119 118400813

OMM:	135509020 135524100(mapk8ip1a) 135536764 135553115

OCLA:

139383002 139385284 139408392 139411278

SALP:

111952786 111962750 111974699 112080729

SNH:	120052013(mapk8ip1b) 120053312(mapk8ip1a) 120065885

CCLU:

121531651 121577042(mapk8ip1a) 121580061 123492135

ELS:	105018289(mapk8ip1)

OEP:	134021067(mapk8ip1a) 134028263(mapk8ip1b)

SFM:	108941304(mapk8ip1)

PKI:	111840847(mapk8ip1)

AANG:

118215059 118228351

AROT:

135241814 135255274

CCOG:

133111833 133130864

LOC:	102691719(mapk8ip1)

PSPA:

121295130 121330422

ARUT:

117432373 117434568

PSEX:

120526165

LCM:	102366999(MAPK8IP1)

CMK:	103175051(mapk8ip1b)

RTP:	109928090(mapk8ip1b)

CPLA:

122557706(mapk8ip1b)

HOC:	132824240(mapk8ip1b)

LERI:

129705628(mapk8ip1b)

PMRN:

LRJ:

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CIN:

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BMOR:

BMAN:

DPL:	KGM_206788

PRAP:

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LGLY:

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API:

AGS:

RMD:

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VDE:

VJA:

CSCU:

NAI:	NECAME_03900

LOA:	LOAG_18610

TSP:

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BGT:

GAE:

HRF:

HRJ:

MYI:

PMAX:

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OBI:

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NVE:

EPA:

ATEN:

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AMIL:

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MFOO:

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HMG:

HSY:

Reference

PMID:9235893

Authors

Dickens M, Rogers JS, Cavanagh J, Raitano A, Xia Z, Halpern JR, Greenberg ME, Sawyers CL, Davis RJ

Title

A cytoplasmic inhibitor of the JNK signal transduction pathway.

Journal

Science 277:693-6 (1997)
DOI:10.1126/science.277.5326.693

Sequence

[hsa:9479]

LinkDB

DBGET integrated database retrieval system