KEGG ORTHOLOGY: K06472

KEGG

ORTHOLOGY: K06472

Entry

K06472                      KO

Symbol

FCGR2A, CD32

Name

low affinity immunoglobulin gamma Fc receptor II-a

Pathway

Phagocytosis

Osteoclast differentiation

Platelet activation

Neutrophil extracellular trap formation

Fc gamma R-mediated phagosome formation

Pathogenic Escherichia coli infection

Yersinia infection

Leishmaniasis

Staphylococcus aureus infection

Tuberculosis

Coronavirus disease

Systemic lupus erythematosus

Disease

Systemic lupus erythematosus

Cystic fibrosis

Malaria

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   04613 Neutrophil extracellular trap formation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   04666 Fc gamma R-mediated phagosome formation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05135 Yersinia infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05150 Staphylococcus aureus infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05152 Tuberculosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Fc receptors
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
CD molecules [BR:ko04090]
Proteins
  K06472  CD32a, FCGR2A; Fc fragment of IgG, low affinity IIa, receptor for (CD32)

Other DBs

GO:

Genes

HSA:	2212(FCGR2A)

PTR:	450194(FCGR2A)

PPS:

GGO:	101130688(FCGR2A)

PON:	100455333(FCGR2A)

PPYG:

129036184(FCGR2A)

NLE:	101176530(FCGR2A)

HMH:	116473329(FCGR2A)

SSYN:

MCC:	719996(FCGR2A)

MCF:	102143568(FCGR2A)

CSAB:

103223676(FCGR2A)

CATY:

105589239(FCGR2A)

PANU:

101009922(FCGR2A)

TGE:	112609477(FCGR2A)

MLEU:

105551007(FCGR2A) 105551015

RRO:	104669518(FCGR2A)

RBB:	108542586(FCGR2A)

TFN:	117074579(FCGR2A)

PTEH:

111525036(FCGR2A)

CANG:

105519604(FCGR2A)

CJC:	100387574(FCGR2A)

SBQ:	101040113(FCGR2A)

CIMI:

108293619(FCGR2A)

ANAN:

105715309(FCGR2A)

CSYR:

103256413(FCGR2A)

MMUR:

105873561(FCGR2A)

ERUF:

138390743(FCGR2A)

PCOQ:

105806468(FCGR2A)

OGA:	100959832(FCGR2A)

MMU:	14131(Fcgr3)

MCAL:

MPAH:

RNO:	134481532 498276(Fcgr2al1)

MCOC:

116103299(Fcgr2a)

ANU:	117712636(Fcgr2a)

MMIU:

308437555(LOC308437555)

MUN:	110554429(Fcgr2a)

CGE:

MAUA:

PROB:

127223560(Fcgr2a)

PLEU:

119086087(Fcgr2a)

PMAV:

MORG:

121442024 121455102

MFOT:

126496491 126496539 126511151

AAMP:

119827207(Fcgr2a)

NGI:	103746769(Fcgr2a)

HGL:	101700630(Fcgr2a)

CPOC:

101787193(Fcgr2a)

CCAN:

109693506(Fcgr2a)

DORD:

DSP:

DMER:

PLOP:

NCAR:

MMMA:

107147464(Fcgr2a)

ITI:	101954523(Fcgr2a)

OCU:

OPI:

OCZ:

GVR:	103582477(FCGR2A)

BTA:	782652(FCGR2A)

BOM:

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

CSUM:

CCAD:

MREE:

136176516(FCGR2A)

OVR:	110125757(FCGR2A)

MBEZ:

SSC:

CFR:

CBAI:

CDK:

BACU:

BMUS:

LVE:

LALB:

DDP:	132438842(FCGR2A)

PCAD:

PSIU:

PPHC:

ECB:	100051733 100065733 100147417

EPZ:	103540857(FCGR2A) 103540858

EAI:	106828032 106831115(FCGR2A)

MYB:

MYD:

MMYO:

MLF:

MDT:

MYUM:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

MMF:

PALE:

RAY:

SFUM:

LAV:	104846329(FCGR2A)

TMU:

PCW:	110209907 110209911

TVP:	118846723 118846725 118847661

PBRV:

138166192 138166194

TACU:

ZLE:

PDAB:

TRU:

TFS:

TBEN:

117469800 117469831 117469832

PGEO:

117443069 117443075

GACU:

117550342 117550344

EMAC:

134876195 134876211

ELY:	117245710 117245912 117245954 117245957 144459698

EFO:	125883976 125884181 125884440

PLEP:

121938216 121938869 121962492

SLUC:

116037670 116052089

ECRA:

ESP:

PFLV:

114545541 114546200

PPUG:

AFB:	129093653 129116533 129116537

CLUM:

CANA:

CVE:	137870676 137870677 137874501

MSAM:

119894681 119913022 119913023

SCHU:

122869696 122870258

EARM:

CUD:	121504085 121504770

SPUL:

LMIX:

HTC:	141811230 141811244 141811245

ALAT:

ASTR:

PKLU:

139222563 139223084

LCO:

OAU:	116318550 120437377

OLA:

OML:

CSAI:

XMA:	111611193 111611255

XCO:

XHE:	116732172 116732504 116733134

PRET:

103460539 103480243 103480863

PFOR:

103129349 103129350 103130536 103130986 103131813

PLAI:

106935121 106938394 106940071 106940659 106941699

PMEI:

106905133 106910704 106912573 106912574

GAF:	122820581 122820714 122821047

PPRL:

129351343 129351368 129352352 129376493 129376544 129376589

CTUL:

119796607 119798683

GMU:	124880301 124880423 124880923 124881269

KMR:

LTU:	140281724 140282295

MCEP:

124996001 125016074

EJA:	138212012 138214181

BFRE:

SSEN:

SSOE:

SMAU:

XGL:

BPEC:

BSPL:

114869016 114869108

SJO:	128383548 128383594 128383613 128384122

SSCO:

SASA:

SALP:

ELS:

Reference

Authors

Stuart SG, Trounstine ML, Vaux DJ, Koch T, Martens CL, Mellman I, Moore KW

Title

Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).

Journal

J Exp Med 166:1668-84 (1987)
DOI:10.1084/jem.166.6.1668

Sequence

[hsa:2212]

Reference

Authors

Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD

Title

Structural recognition and functional activation of FcgammaR by innate pentraxins.

Journal

Nature 456:989-92 (2008)
DOI:10.1038/nature07468

LinkDB

DBGET integrated database retrieval system