Homo sapiens (human): 2212
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Entry
2212 CDS
T01001
Symbol
FCGR2A, CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, FcgammaRIIa, IGFR2
Name
(RefSeq) low affinity immunoglobulin gamma Fc region receptor II-a isoform 1 precursor
KO
K06472
low affinity immunoglobulin gamma Fc receptor II-a
Organism
hsa
Homo sapiens (human)
Pathway
hsa04145
Phagosome
hsa04380
Osteoclast differentiation
hsa04611
Platelet activation
hsa04613
Neutrophil extracellular trap formation
hsa04666
Fc gamma R-mediated phagosome formation
hsa05130
Pathogenic Escherichia coli infection
hsa05135
Yersinia infection
hsa05140
Leishmaniasis
hsa05150
Staphylococcus aureus infection
hsa05152
Tuberculosis
hsa05171
Coronavirus disease - COVID-19
hsa05322
Systemic lupus erythematosus
Network
nt06180
Pathogenic Escherichia coli
nt06183
Yersinia
Element
N01090
IGG-FCGR-RAC signaling pathway
N01091
Escherichia EspJ to IGG-FCGR-RAC signaling pathway
Disease
H00080
Systemic lupus erythematosus
H00218
Cystic fibrosis
H00361
Malaria
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
2212 (FCGR2A)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
2212 (FCGR2A)
04613 Neutrophil extracellular trap formation
2212 (FCGR2A)
04666 Fc gamma R-mediated phagosome formation
2212 (FCGR2A)
09158 Development and regeneration
04380 Osteoclast differentiation
2212 (FCGR2A)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
2212 (FCGR2A)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
2212 (FCGR2A)
05135 Yersinia infection
2212 (FCGR2A)
05150 Staphylococcus aureus infection
2212 (FCGR2A)
05152 Tuberculosis
2212 (FCGR2A)
09174 Infectious disease: parasitic
05140 Leishmaniasis
2212 (FCGR2A)
09163 Immune disease
05322 Systemic lupus erythematosus
2212 (FCGR2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
2212 (FCGR2A)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hsa04090
]
2212 (FCGR2A)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Phagocytosis
Fc receptors
2212 (FCGR2A)
CD molecules [BR:
hsa04090
]
Proteins
2212 (FCGR2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ig_2
Ig_3
ig
Ig_4
I-set
Ig_5
Big_7
V-set_CD47
ECSCR
Motif
Other DBs
NCBI-GeneID:
2212
NCBI-ProteinID:
NP_001129691
OMIM:
146790
HGNC:
3616
Ensembl:
ENSP00000271450.6
UniProt:
P12318
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:161505457..161524048
Genome browser
AA seq
317 aa
AA seq
DB search
MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL
TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL
SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS
HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY
CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD
KNIYLTLPPNDHVNSNN
NT seq
954 nt
NT seq
+upstream
nt +downstream
nt
atgactatggagacccaaatgtctcagaatgtatgtcccagaaacctgtggctgcttcaa
ccattgacagttttgctgctgctggcttctgcagacagtcaagctgcagctcccccaaag
gctgtgctgaaacttgagcccccgtggatcaacgtgctccaggaggactctgtgactctg
acatgccagggggctcgcagccctgagagcgactccattcagtggttccacaatgggaat
ctcattcccacccacacgcagcccagctacaggttcaaggccaacaacaatgacagcggg
gagtacacgtgccagactggccagaccagcctcagcgaccctgtgcatctgactgtgctt
tccgaatggctggtgctccagacccctcacctggagttccaggagggagaaaccatcatg
ctgaggtgccacagctggaaggacaagcctctggtcaaggtcacattcttccagaatgga
aaatcccagaaattctcccatttggatcccaccttctccatcccacaagcaaaccacagt
cacagtggtgattaccactgcacaggaaacataggctacacgctgttctcatccaagcct
gtgaccatcactgtccaagtgcccagcatgggcagctcttcaccaatggggatcattgtg
gctgtggtcattgcgactgctgtagcagccattgttgctgctgtagtggccttgatctac
tgcaggaaaaagcggatttcagccaattccactgatcctgtgaaggctgcccaatttgag
ccacctggacgtcaaatgattgccatcagaaagagacaacttgaagaaaccaacaatgac
tatgaaacagctgacggcggctacatgactctgaaccccagggcacctactgacgatgat
aaaaacatctacctgactcttcctcccaacgaccatgtcaacagtaataactaa
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