KEGG ORTHOLOGY: K06981

ORTHOLOGY: K06981

Entry

K06981                      KO

Symbol

ipk

Name

isopentenyl phosphate kinase [EC:2.7.4.26]

Pathway

map00900

Terpenoid backbone biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00849

C5 isoprenoid biosynthesis, mevalonate pathway, archaea

Reaction

R10093

ATP:isopentenyl phosphate phosphotransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K06981  ipk; isopentenyl phosphate kinase
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.26  isopentenyl phosphate kinase
     K06981  ipk; isopentenyl phosphate kinase

Other DBs

COG:

COG1608

Genes

ASN:

AMJ:

CPOO:

TST:

MRV:

ACS:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

EMC:

MUO:

GSH:

CMK:

BFO:

BBEL:

SPU:

APLC:

ARUN:

HAME:

CQD:

LGI:	LOTGIDRAFT_238298

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

MYI:

PMAX:

MMER:

RPHI:

LJP:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

TAD:	TRIADDRAFT_51825

ATH:

AT1G26640

ALY:

9329452

CRB:

17899902

CSAT:

104741189 104756878 104776619

EUS:	EUTSA_v10008165mg

BRP:

103840631

BNA:	106360561(BNAC05G20190D) 125578013

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10031995mg

PVY:	116120596 116121375

MINC:

TCC:

GRA:

GHI:

GAB:

HSYR:

DZI:

EGR:

GMX:

GSJ:

PVU:	PHAVU_002G091000g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:	101491500(288)

PSAT:

127119609

VVO:	131646511 131651694

LJA:

130739779

ADU:

107489266

AIP:

107643569

AHF:	112750238 112801549

LANG:

109359013

PCIN:

129321401

QSA:	O6P43_032959

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

PNZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107793526 107805486

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111398337 111398921

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110706388 110713255

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119269101 119277091

TAES:

123062154 123070881 123079271

TUA:

125544869

LPER:

127339871 127343703

LRD:	124660852 124663156 124667919 124690211

SBI:

8079244

ZMA:	100191244 103652468

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	122020163 122023954

DCT:	110099259 110099419

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_136903 SELMODRAFT_92970

PPP:	112280543 112285657

CRE:	CHLRE_13g579800v5

VCN:	VOLCADRAFT_89200

MNG:

MNEG_4828

CVR:	CHLNCDRAFT_12639

OLU:	OSTLU_92808

OTA:	OT_ostta05g04420

BPG:	Bathy03g05220

MIS:	MICPUN_76277

MPP:	MICPUCDRAFT_70280

MAW:	19250312(J3458_020782)

MAJ:

MAA_09148

MBRN:

26245030(MTH_47)

PCHM:

VFPPC_05924

CMT:

CCM_06064

AMUS:

LMH87_005315

DDI:	DDB_G0288029

DPP:	DICPUDRAFT_152394

DFA:

DFA_09969

FCY:	FRACYDRAFT_235467

TPS:	THAPSDRAFT_11228

EHX:	EMIHUDRAFT_103456 EMIHUDRAFT_114408

NGR:	NAEGRDRAFT_61783

SDN:

Sden_1166

CVI:

CV_3960

CVC:	BKX93_17520

CHRI:

DK842_11805

CHRB:

DK843_17240

BRY:	M0696_19620

FAF:	OE104_11350

BHUI:

PAUS:

NAKE:

MCAY:

NSH:

NPZ:	ACX27_00200

RRS:	RoseRS_2247

RCA:

Rcas_4059

CAU:

Caur_0506

CHL:	Chy400_0542

CAG:

HAU:

ATM:

ABAT:

PSUB:

ABAO:

CAP:	CLDAP_05580

PBF:	CFX0092_A0137

THUG:

KNN16_12765

PMET:

G4Y79_16160

MJA:

MJ_0044

MFE:	Mefer_0425

MVU:	Metvu_0307

MFS:	MFS40622_0936

MIF:	Metin_0190

MJH:	JH146_1549

MESG:

MLAUSG7_0754

MESA:

MLASG1_0439

MIG:	Metig_0202

MMP:

MMP1645

MMQ:	MmarC5_1763

MMX:	MmarC6_1026

MMZ:	MmarC7_0918

MMD:

MMAK:

MMAO:

MMAD:

MAE:

MVN:	Mevan_0950

MVO:

Mvol_1261

MOK:	Metok_0924

METF:

CFE53_02940

MTH:

MTH_47

MMG:	MTBMA_c05360

MWO:	MWSIV6_0501

MTEE:

MTTB_10950

METC:

MTCT_0046

METE:

tca_00047(proB)

METZ:

METK:

MTHM:

METJ:

MST:

METB:

MEIS:

MRU:

MSI:

MEB:

MMIL:

MEYE:

MOL:

MARO:

METV:

MEL:	Metbo_0819

MEW:	MSWAN_1426

METH:

MBMB1_0812

MFC:

BRM9_0362

MFI:	DSM1535_0289

MCUB:

MSUB:

METN:

METT:

METO:

MEME:

MFEG:

MFV:

MKA:

AFU:

APO:	Arcpr_1564

AVE:	Arcve_0600

AST:	Asulf_00536

FPL:

GAC:

GAH:

PFU:

PFI:

PHO:	PH1623(PH1623)

PAB:	PAB0373(argB-like)

PYN:

PNA2_0206

PYA:	PYCH_02620

PYS:

Py04_1517

PYC:	TQ32_08705

TKO:

TK1473

TON:

TON_0134

TGA:	TGAM_1729(fomA)

TSI:

TSIB_1230

TBA:	TERMP_00144

THE:

THA:

THM:

TLT:

THS:

TNU:

TEU:

TGY:	X802_01560

THV:	ADU37_CDS09070 ADU37_CDS09160

TCH:	CHITON_1859

TPEP:

A0127_07835

TPIE:

A7C91_06635

TGG:	A3K92_01380

TCE:	A3L02_00085

TBS:	A3L01_01380

THH:	CDI07_01360

TSL:	A3L11_05130

TTD:	A3L14_02860

TPRF:

A3L09_04260

TRL:	A3L10_05185

TPAF:

A3L08_04390

THY:	A3L12_00935

TIC:	FH039_03260

TCQ:	TIRI35C_0496

THEM:

FPV09_05955

THEI:

K1720_09230

PPAC:

PAP_01960

MBA:	Mbar_A1420

MBY:	MSBRM_0484

MBW:	MSBRW_3307

MBAR:

MBAK:

MAC:

MMA:

MMJ:	MSMAS_2915

MMAC:

MSMAC_1518

MVC:	MSVAZ_0528

MEK:	MSKOL_0507

MLS:	MSLAZ_0337

METM:

MSMTP_2866

MEF:	MSWH1_2735

MEQ:	MSWHS_2303

MSJ:	MSSAC_0532

MSZ:	MSSIH_0494

MSW:	MSSIT_0517

MTHR:

MSTHT_2118

MTHE:

MSTHC_1166

MHOR:

MSHOH_3625

MFZ:	AOB57_005355

MBU:

MMET:

MELO:

MMH:

MHAZ:

MPOT:

MEV:	Metev_0322

MZH:	Mzhil_1008

MPY:

Mpsy_0884

MZI:	HWN40_04230

MMAV:

RE476_06060

MSEB:

RE474_02485

MHZ:	Metho_1634

MEHF:

MmiHf6_06660(argB_1)

MEES:

MmiEs2_03450(argB_1)

MTP:

MCJ:

MHI:

MHU:

MRTJ:

MLA:

MEM:	Memar_1813

MBG:	BN140_0575

MEMA:

MMAB1_0740

MCHK:

MchiMG62_20760

MSUM:

OH143_03290

MRC:	R6Y96_08745

MPI:

MEND:

MEFW:

MAQE:

MFK:	E2N92_09760

MOU:	OU421_12780

MESB:

L1S32_04535

MANQ:

L1994_07755

MBN:

Mboo_2212

MFO:	Metfor_0496

MPL:

MPD:

MEZ:

RCI:

MJK:	N2V74_01035 N2V74_04825

HAL:	VNG_1148G(argB)

HSL:

OE_2647F

HANR:

LJ422_04695

HDL:	HALDL1_11700

HHB:

Hhub_2771

HAGS:

JT689_06000

HABO:

JRZ79_04465

HNO:	LT974_10940

HLU:	LT972_04630

HALH:

HTSR_0764

HHSR:

HSR6_0790

HSU:	HLASF_1451

HSF:	HLASA_1438

HAHS:

HSRCO_1993

SALR:

FQU85_08325

HALR:

EFA46_008415

HJE:	HacjB3_08705

HDO:	MUK72_12110

HALX:

HAXZ:

HAYC:

HAXY:

SALI:

SAIM:

HARA:

HMA:	rrnAC0078(argB1)

HHI:	HAH_0835(argB1)

HHN:	HISP_04320

HAB:	SG26_12035

HTA:	BVU17_04105

HALJ:

HSIN:

NPH:

NMO:

NHO:	HWV23_00010

NSAL:

HUT:

HTI:

HALA:

HASV:

SVXHr_2646(ipk)

HABN:

HBNXHr_2478(ipk)

HMU:

Hmuk_2605

HALZ:

E5139_00310

HALL:

LC1Hm_1949(ipk)

HAZP:

GBQ70_00310

HALI:

BV210_01175

HSN:	DV733_03775

HDS:	HSR122_2117

HRR:	HZS55_19070

HPEL:

HZS54_23245

HLT:	I7X12_16320

HARC:

SSAI:

HAAD:

HWA:

HWC:

HVO:

HALE:

HLN:	SVXHx_1839(ipk)

HME:

HFX_2774

HGI:	ABY42_13835

HLS:	KU306_14745

HBO:	Hbor_12300

HAQ:	DU484_10955

HAJ:	DU500_11220

HAER:

DU502_08605

HRA:	EI982_17310

HLM:	DV707_05560

HALM:

HLA:

HALP:

HALB:

HEZZ:

HALQ:

HSS:	J7656_05985

HSAI:

HPS36_11195

HAZZ:

KI388_08785

SRUB:

C2R22_12520

HAE:	halTADL_0076

HALN:

B4589_004970

HALG:

HUG10_04465

HALU:

HUG12_12495

HMP:	K6T50_02540

HRE:	K6T36_02375

HRM:	K6T25_14045

HACB:

Hbl1158_09415

HDF:	AArcSl_2732(ipk)

HAH:	Halar_1546

HTU:

HSAL:

HAKZ:

NMG:

HXA:	Halxa_0730

NAT:

NJ7G_1104

NPE:	Natpe_1689

NVR:	FEJ81_08690

NPL:	FGF80_03245

NAY:	HYG81_01025

HALY:

HYG82_04865

HJT:	DVR14_17930 DVR14_22060

HLO:	J0X27_14645

NGE:	Natgr_2566

HRU:	Halru_1739

SAWL:

NGM29_07780

HALV:

NGM15_00010

NOU:	Natoc_1801

HLR:	HALLA_13925

HLC:	CHINAEXTREME11300

NAJ:	B1756_02530

NAG:	AArcMg_2526

NAN:	AArc1_1200

NARA:

QQ977_02945

NBG:	DV706_11915

NAS:	GCU68_00165

HDA:	BB347_07640

MELU:

MEAM:

MEAE:

TAC:

TVO:	TVG0187430(TVG0187430)

PTO:

PTO0497

FAC:	FACI_IFERC01G0945

FAI:

FAD_1830

CDIV:

CPM_0049

TAR:	TALC_01359

MAX:	MMALV_14490

MER:	MMINT_05450

MEAR:

Mpt1_c00630

MEUZ:

KRP56_07065

MARC:

AR505_0192

ABI:	Aboo_0423 Aboo_0725

ACF:	AciM339_0341 AciM339_0399 AciM339_0625

APE:	APE_1768.1

ACJ:

ACAM_1109

SMR:

Smar_0511

SHC:	Shell_0286

IHO:

Igni_0566

IIS:

EYM_04880

DKA:

DKAM_1442

DFD:	Desfe_0065

DMU:	Desmu_1042

TAG:

Tagg_1081

IAG:

Igag_0200

THG:	TCELL_0752

HBU:

Hbut_0538

PFM:	Pyrfu_0915

PDL:	Pyrde_2023

PABI:

PARE:

SSO:

SOL:

SSOA:

SSOL:

SSOF:

SSHI:

SCAS:

SIS:	LS215_2221

SIA:	M1425_2056

SIM:	M1627_2136

SID:

M164_2063

SIY:	YG5714_2182

SIN:	YN1551_0737

SII:

SIH:

SIR:

SIC:

SULA:

SULE:

SULO:

MSE:

MEMJ:

MCN:

MHK:	DFR87_07785

MPRU:

DFR88_07455

MTEN:

GWK48_04365

MJN:	MjAS7_0448

AHO:

AMAN:

ABRI:

ASUL:

AAMB:

ACIH:

STEP:

SMET:

PAI:

PIS:

PCL:

PAS:

PYR:

POG:

TNE:

PYW:	PYWP30_00187

CMA:

TTN:

TUZ:

VDI:

VMO:

TPE:

THB:	N186_04380

TCB:	TCARB_1903

THEL:

IG193_04520

ASC:

ASAC_0904

ACIA:

SE86_05200

CLG:	Calag_0846

FFO:	FFONT_0456

KCR:

Kcr_1595

NMR:

Nmar_0314

NIR:	NSED_01515

NKR:	NKOR_01425

NID:	NPIRD3C_0716

NIN:	NADRNF5_1938

NIW:	Nisw_03345

NCL:	C5F47_01680

NOX:	C5F49_01675

NUE:	C5F50_02280

NIP:	NsoK4_07205

NZT:	NZOSNM25_001726

NCT:

NMSP_1394

NIC:	DSQ20_01830

NGA:	Ngar_c21610

NVN:	NVIE_008070

NEV:

NTE_02263

TAA:	NMY3_02132

NFN:	NFRAN_2921

NCV:

NCAV_1517

CSY:	CENSYa_1615

CSU:	CSUB_C0425

NBV:

T478_0246

TAH:	SU86_004395

NIU:	DSQ19_01720

NDV:

CCAI:

BARC:

BARB:

MARH:

FLT:	Sv326_0061

MIY:	Micr_00463

LOKI:

Lokiarch_22770

LOB:	NEF87_003597

PSYT:

DSAG12_01210 DSAG12_02985

» show all

Reference

PMID:16621811

Authors

Grochowski LL, Xu H, White RH

Title

Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate.

Journal

J Bacteriol 188:3192-8 (2006)
DOI:10.1128/JB.188.9.3192-3198.2006

Sequence

[mja:MJ_0044]

Reference

PMID:26216978

Authors

Henry LK, Gutensohn M, Thomas ST, Noel JP, Dudareva N

Title

Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants.

Journal

Proc Natl Acad Sci U S A 112:10050-5 (2015)
DOI:10.1073/pnas.1504798112

Sequence

[ath:AT1G26640]

LinkDB

ENZYME: 2.7.4.26

Entry

EC 2.7.4.26                 Enzyme

Name

isopentenyl phosphate kinase;
ATP:isopentenyl phosphate phosphotransferase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor

Sysname

ATP:3-methylbut-3-en-1-yl-phosphate phosphotransferase

Reaction(IUBMB)

ATP + 3-methylbut-3-en-1-yl phosphate = ADP + 3-methylbut-3-en-1-yl diphosphate [RN:R10093]

Reaction(KEGG)

R10093

Substrate

ATP [CPD:C00002];
3-methylbut-3-en-1-yl phosphate [CPD:C20345]

Product

ADP [CPD:C00008];
3-methylbut-3-en-1-yl diphosphate [CPD:C00129]

Comment

The enzyme is involved in the mevalonate pathway in Archaea [1]. The activity has also been identified in the plant Mentha piperita (peppermint) [2]. It is strictly specific for ATP but can use other phosphate acceptors such as prenyl phosphate, geranyl phosphate, or fosfomycin.

History

EC 2.7.4.26 created 2012

Pathway

ec00900

Terpenoid backbone biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K06981

isopentenyl phosphate kinase

Genes

ASN:

106723108

AMJ:

106737678

CPOO:

109317576

TST:

117877258

MRV:

120404739

ACS:

103278744

ASAO:

132773329

PVT:

110073401

SUND:

121928951

PBI:

103049702

PMUR:

107287790

CTIG:

120301787

TSR:

106539195

PGUT:

117663776

APRI:

131195429

PTEX:

113444277

NSS:

113420760

VKO:

123032206

PMUA:

114599410

PRAF:

128416223

ZVI:

118089509

HCG:

128323006

GJA:

107107948

EMC:

129329603

MUO:

115481930

GSH:

117347485

CMK:

103179096

BFO:

118413305

BBEL:

109475511

SPU:

100890155

APLC:

110979072

ARUN:

117302455

HAME:

121862232

CQD:

128694350

LGI:	LOTGIDRAFT_238298

PVUL:

126831491

PCAN:

112564276

BGT:

106074055

GAE:

121380859

HRF:

124131008

HRJ:

124287065

MYI:

110461970

PMAX:

117343856

MMER:

123531596

RPHI:

132750498 132753777

LJP:

135471834

LAK:

106152890

NVE:

5515104

EPA:

110242649

ATEN:

116300256

ADF:

107347187

AMIL:

114966446

PDAM:

113684719

SPIS:

111323292

TAD:	TRIADDRAFT_51825

ATH:

AT1G26640

ALY:

9329452

CRB:

17899902

CSAT:

104741189 104756878 104776619

EUS:	EUTSA_v10008165mg

BRP:

103840631

BNA:	106360561(BNAC05G20190D) 125578013

BOE:

106343097

RSZ:

108813740

THJ:

104808621

CPAP:

110824151

CIT:

102621982

CIC:	CICLE_v10031995mg

PVY:	116120596 116121375

MINC:

123213209

TCC:

18610326

GRA:

105783960

GHI:

107893867

GAB:

108461668

HSYR:

120118198 120170909

DZI:

111281867

EGR:

104433419

GMX:

100792453

GSJ:

114386983

PVU:	PHAVU_002G091000g

VRA:

106755265

VAR:

108336004

VUN:

114169739

VUM:

124826369

CCAJ:

109803037

APRC:

113869974

MTR:

11417595

TPRA:

123905075

CAM:	101491500(288)

PSAT:

127119609

VVO:	131646511 131651694

LJA:

130739779

ADU:

107489266

AIP:

107643569

AHF:	112750238 112801549

LANG:

109359013

PCIN:

129321401

QSA:	O6P43_032959

FVE:

101295219

RCN:

112197842

PPER:

18789342

PMUM:

103321523

PAVI:

110751257

PDUL:

117619058 117637975

MDM:

103423801

MSYL:

126595038

PXB:

103947215

ZJU:

107429028

MNT:

21398807

CSAV:

115698781

CSV:

101216243

CMO:

103503361

BHJ:

120079784

MCHA:

111025262

CMAX:

111493614

CMOS:

111450692

CPEP:

111783871

RCU:

8289160

MEAN:

126687708

JCU:

105630501

HBR:

110643207

MESC:

110625733

POP:

7492908

PEU:

105116803

PALZ:

118042996

PNZ:

133697399

JRE:

109019800

CILL:

122313357

CAVE:

132177343

QSU:

112009069

QLO:

115978810

TWL:

120001932

VVI:

100247979

VRI:

117912870

SLY:

101250107

SPEN:

107017971

SOT:

102588327

SSTN:

125854333

SDUL:

129870538

CANN:

107871289

LBB:

132613579

NTA:	107793526 107805486

NSY:

104225818

NTO:

104108659

NAU:

109240151

INI:

109162071

ITR:

116015368

SIND:

105160005

OEU:	111398337 111398921

EGT:

105967535

SSPL:

121768346

SMIL:

130995845

SHIS:

125201114

APAN:

127245317

HAN:

110871873

ECAD:

122606880

LSV:

111902634

CCAV:

112525640

DCR:

108200374

CSIN:

114280717

RVL:

131311269

AEW:

130779427

BVG:

104897837

SOE:

110777852

CQI:	110706388 110713255

ATRI:

130820685

MOF:

131143734

NNU:

104598036

MING:

122077143

TSS:

122654270

PSOM:

113299878 113300252

OSA:

4326891

OBR:

102707821

OGL:

127784836

BDI:

100832959

ATS:

109753727

TDC:	119269101 119277091

TAES:

123062154 123070881 123079271

TUA:

125544869

LPER:

127339871 127343703

LRD:	124660852 124663156 124667919 124690211

SBI:

8079244

ZMA:	100191244 103652468

MFLO:

136453044 136453303

SITA:

101785538

SVS:

117856785

PVIR:

120672214 120708153

PHAI:

112892982

PDA:

103700858

EGU:

105057791

MUS:

103975627

ZOF:	122020163 122023954

DCT:	110099259 110099419

PEQ:

110029254

AOF:

109849095

MSIN:

131228538

NCOL:

116257507 116268168

ATR:

18434727

SMO:	SELMODRAFT_136903 SELMODRAFT_92970

PPP:	112280543 112285657

CRE:	CHLRE_13g579800v5

VCN:	VOLCADRAFT_89200

MNG:

MNEG_4828

CVR:	CHLNCDRAFT_12639

OLU:	OSTLU_92808

OTA:	OT_ostta05g04420

BPG:	Bathy03g05220

MIS:	MICPUN_76277

MPP:	MICPUCDRAFT_70280

MAW:	19250312(J3458_020782)

MAJ:

MAA_09148

MBRN:

26245030(MTH_47)

PCHM:

VFPPC_05924

CMT:

CCM_06064

AMUS:

LMH87_005315

DDI:	DDB_G0288029

DPP:	DICPUDRAFT_152394

DFA:

DFA_09969

FCY:	FRACYDRAFT_235467

TPS:	THAPSDRAFT_11228

EHX:	EMIHUDRAFT_103456 EMIHUDRAFT_114408

NGR:	NAEGRDRAFT_61783

SDN:

Sden_1166

CVI:

CV_3960

CVC:	BKX93_17520

CHRI:

DK842_11805

CHRB:

DK843_17240

BRY:	M0696_19620

FAF:	OE104_11350

BHUI:

LOK74_22675

PAUS:

NCTC13651_00687

NAKE:

KGD83_08815

MCAY:

PVK37_05210

NSH:

GXM_10396

NPZ:	ACX27_00200

RRS:	RoseRS_2247

RCA:

Rcas_4059

CAU:

Caur_0506

CHL:	Chy400_0542

CAG:

Cagg_3216

HAU:

Haur_2285

ATM:

ANT_15950

ABAT:

CFX1CAM_1693

PSUB:

Pelsub_P1567

ABAO:

BEQ56_06645

CAP:	CLDAP_05580

PBF:	CFX0092_A0137

THUG:

KNN16_12765

PMET:

G4Y79_16160

MJA:

MJ_0044

MFE:	Mefer_0425

MVU:	Metvu_0307

MFS:	MFS40622_0936

MIF:	Metin_0190

MJH:	JH146_1549

MESG:

MLAUSG7_0754

MESA:

MLASG1_0439

MIG:	Metig_0202

MMP:

MMP1645

MMQ:	MmarC5_1763

MMX:	MmarC6_1026

MMZ:	MmarC7_0918

MMD:

GYY_09080

MMAK:

MMKA1_18770

MMAO:

MMOS7_17590

MMAD:

MMJJ_11920

MAE:

Maeo_1031

MVN:	Mevan_0950

MVO:

Mvol_1261

MOK:	Metok_0924

METF:

CFE53_02940

MTH:

MTH_47

MMG:	MTBMA_c05360

MWO:	MWSIV6_0501

MTEE:

MTTB_10950

METC:

MTCT_0046

METE:

tca_00047(proB)

METZ:

METMT2_0295

METK:

FVF72_01865

MTHM:

FZP57_02375

METJ:

FZP68_07395

MST:

Msp_0857

METB:

AW729_01825

MEIS:

PXD04_09815

MRU:

mru_0921

MSI:

Msm_1440

MEB:

Abm4_1229

MMIL:

sm9_1640

MEYE:

TL18_07255

MOL:

YLM1_0486

MARO:

MarbSA_06150

METV:

K4897_08025

MEL:	Metbo_0819

MEW:	MSWAN_1426

METH:

MBMB1_0812

MFC:

BRM9_0362

MFI:	DSM1535_0289

MCUB:

MCBB_1337

MSUB:

BK009_04660

METN:

BK008_00135

METT:

CIT01_08910

METO:

CIT02_00415

MEME:

HYG87_09360

MFEG:

GCM10025860_24840

MFV:

Mfer_0896

MKA:

MK0777

AFU:

AF_2288

APO:	Arcpr_1564

AVE:	Arcve_0600

AST:	Asulf_00536

FPL:

Ferp_1382

GAC:

GACE_1301

GAH:

GAH_00188

PFU:

PF1636

PFI:

PFC_10425

PHO:	PH1623(PH1623)

PAB:	PAB0373(argB-like)

PYN:

PNA2_0206

PYA:	PYCH_02620

PYS:

Py04_1517

PYC:	TQ32_08705

TKO:

TK1473

TON:

TON_0134

TGA:	TGAM_1729(fomA)

TSI:

TSIB_1230

TBA:	TERMP_00144

THE:

GQS_04565

THA:

TAM4_1700

THM:

CL1_0568

TLT:

OCC_01024

THS:

TES1_0236

TNU:

BD01_2227

TEU:

TEU_05465

TGY:	X802_01560

THV:	ADU37_CDS09070 ADU37_CDS09160

TCH:	CHITON_1859

TPEP:

A0127_07835

TPIE:

A7C91_06635

TGG:	A3K92_01380

TCE:	A3L02_00085

TBS:	A3L01_01380

THH:	CDI07_01360

TSL:	A3L11_05130

TTD:	A3L14_02860

TPRF:

A3L09_04260

TRL:	A3L10_05185

TPAF:

A3L08_04390

THY:	A3L12_00935

TIC:	FH039_03260

TCQ:	TIRI35C_0496

THEM:

FPV09_05955

THEI:

K1720_09230

PPAC:

PAP_01960

MBA:	Mbar_A1420

MBY:	MSBRM_0484

MBW:	MSBRW_3307

MBAR:

MSBR2_1898

MBAK:

MSBR3_2037

MAC:

MA_0603

MMA:

MM_1763

MMJ:	MSMAS_2915

MMAC:

MSMAC_1518

MVC:	MSVAZ_0528

MEK:	MSKOL_0507

MLS:	MSLAZ_0337

METM:

MSMTP_2866

MEF:	MSWH1_2735

MEQ:	MSWHS_2303

MSJ:	MSSAC_0532

MSZ:	MSSIH_0494

MSW:	MSSIT_0517

MTHR:

MSTHT_2118

MTHE:

MSTHC_1166

MHOR:

MSHOH_3625

MFZ:	AOB57_005355

MBU:

Mbur_2396

MMET:

MCMEM_0542

MELO:

J7W08_00740

MMH:

Mmah_1550

MHAZ:

BHR79_05975

MPOT:

BKM01_02180

MEV:	Metev_0322

MZH:	Mzhil_1008

MPY:

Mpsy_0884

MZI:	HWN40_04230

MMAV:

RE476_06060

MSEB:

RE474_02485

MHZ:	Metho_1634

MEHF:

MmiHf6_06660(argB_1)

MEES:

MmiEs2_03450(argB_1)

MTP:

Mthe_0475

MCJ:

MCON_2558

MHI:

Mhar_0984

MHU:

Mhun_2889

MRTJ:

KHC33_02505

MLA:

Mlab_0682

MEM:	Memar_1813

MBG:	BN140_0575

MEMA:

MMAB1_0740

MCHK:

MchiMG62_20760

MSUM:

OH143_03290

MRC:	R6Y96_08745

MPI:

Mpet_0760

MEND:

L6E24_04790

MEFW:

F1737_07230

MAQE:

RJ40_09560

MFK:	E2N92_09760

MOU:	OU421_12780

MESB:

L1S32_04535

MANQ:

L1994_07755

MBN:

Mboo_2212

MFO:	Metfor_0496

MPL:

Mpal_2375

MPD:

MCP_1638

MEZ:

Mtc_2284

RCI:

LRC398

MJK:	N2V74_01035 N2V74_04825

HAL:	VNG_1148G(argB)

HSL:

OE_2647F

HANR:

LJ422_04695

HDL:	HALDL1_11700

HHB:

Hhub_2771

HAGS:

JT689_06000

HABO:

JRZ79_04465

HNO:	LT974_10940

HLU:	LT972_04630

HALH:

HTSR_0764

HHSR:

HSR6_0790

HSU:	HLASF_1451

HSF:	HLASA_1438

HAHS:

HSRCO_1993

SALR:

FQU85_08325

HALR:

EFA46_008415

HJE:	HacjB3_08705

HDO:	MUK72_12110

HALX:

M0R89_16920

HAXZ:

M0R88_17205

HAYC:

NGM10_00285

HAXY:

NGM07_03825

SALI:

L593_01905

SAIM:

K0C01_08360

HARA:

AArcS_1353

HMA:	rrnAC0078(argB1)

HHI:	HAH_0835(argB1)

HHN:	HISP_04320

HAB:	SG26_12035

HTA:	BVU17_04105

HALJ:

G9465_13460

HSIN:

KDQ40_09330

NPH:

NP_2852A

NMO:

Nmlp_2741

NHO:	HWV23_00010

NSAL:

HWV07_02360

HUT:

Huta_2046

HTI:

HTIA_1633

HALA:

Hrd1104_07350

HASV:

SVXHr_2646(ipk)

HABN:

HBNXHr_2478(ipk)

HMU:

Hmuk_2605

HALZ:

E5139_00310

HALL:

LC1Hm_1949(ipk)

HAZP:

GBQ70_00310

HALI:

BV210_01175

HSN:	DV733_03775

HDS:	HSR122_2117

HRR:	HZS55_19070

HPEL:

HZS54_23245

HLT:	I7X12_16320

HARC:

HARCEL1_05835

SSAI:

N0B31_06085

HAAD:

MW046_02225

HWA:

HQ_2926A

HWC:

Hqrw_3337

HVO:

HVO_2762

HALE:

G3A49_17500

HLN:	SVXHx_1839(ipk)

HME:

HFX_2774

HGI:	ABY42_13835

HLS:	KU306_14745

HBO:	Hbor_12300

HAQ:	DU484_10955

HAJ:	DU500_11220

HAER:

DU502_08605

HRA:	EI982_17310

HLM:	DV707_05560

HALM:

FCF25_05055

HLA:

Hlac_1830

HALP:

DOS48_08835

HALB:

EKH57_00675

HEZZ:

EO776_10605

HALQ:

Hrr1229_013105

HSS:	J7656_05985

HSAI:

HPS36_11195

HAZZ:

KI388_08785

SRUB:

C2R22_12520

HAE:	halTADL_0076

HALN:

B4589_004970

HALG:

HUG10_04465

HALU:

HUG12_12495

HMP:	K6T50_02540

HRE:	K6T36_02375

HRM:	K6T25_14045

HACB:

Hbl1158_09415

HDF:	AArcSl_2732(ipk)

HAH:	Halar_1546

HTU:

Htur_2540

HSAL:

JMJ58_16130

HAKZ:

J0X25_00010

NMG:

Nmag_0440

HXA:	Halxa_0730

NAT:

NJ7G_1104

NPE:	Natpe_1689

NVR:	FEJ81_08690

NPL:	FGF80_03245

NAY:	HYG81_01025

HALY:

HYG82_04865

HJT:	DVR14_17930 DVR14_22060

HLO:	J0X27_14645

NGE:	Natgr_2566

HRU:	Halru_1739

SAWL:

NGM29_07780

HALV:

NGM15_00010

NOU:	Natoc_1801

HLR:	HALLA_13925

HLC:	CHINAEXTREME11300

NAJ:	B1756_02530

NAG:	AArcMg_2526

NAN:	AArc1_1200

NARA:

QQ977_02945

NBG:	DV706_11915

NAS:	GCU68_00165

HDA:	BB347_07640

MELU:

MTLP_11460

MEAM:

MU439_02995

MEAE:

QEN48_07360

TAC:

Ta0103

TVO:	TVG0187430(TVG0187430)

PTO:

PTO0497

FAC:	FACI_IFERC01G0945

FAI:

FAD_1830

CDIV:

CPM_0049

TAR:	TALC_01359

MAX:	MMALV_14490

MER:	MMINT_05450

MEAR:

Mpt1_c00630

MEUZ:

KRP56_07065

MARC:

AR505_0192

ABI:	Aboo_0423 Aboo_0725

ACF:	AciM339_0341 AciM339_0399 AciM339_0625

APE:	APE_1768.1

ACJ:

ACAM_1109

SMR:

Smar_0511

SHC:	Shell_0286

IHO:

Igni_0566

IIS:

EYM_04880

DKA:

DKAM_1442

DFD:	Desfe_0065

DMU:	Desmu_1042

TAG:

Tagg_1081

IAG:

Igag_0200

THG:	TCELL_0752

HBU:

Hbut_0538

PFM:	Pyrfu_0915

PDL:	Pyrde_2023

PABI:

PABY_20520

PARE:

PYJP_18650

SSO:

SSO0064

SOL:

Ssol_1044

SSOA:

SULA_1081

SSOL:

SULB_1082

SSOF:

SULC_1081

SSHI:

J5U23_00184

SCAS:

SACC_32480

SIS:	LS215_2221

SIA:	M1425_2056

SIM:	M1627_2136

SID:

M164_2063

SIY:	YG5714_2182

SIN:	YN1551_0737

SII:

LD85_2323

SIH:

SiH_2002

SIR:

SiRe_1929

SIC:

SiL_1909

SULA:

BFU36_05525

SULE:

GFS03_11240

SULO:

GFS33_03055

MSE:

Msed_2137

MEMJ:

MJ1HA_2411

MCN:

Mcup_0152

MHK:	DFR87_07785

MPRU:

DFR88_07455

MTEN:

GWK48_04365

MJN:	MjAS7_0448

AHO:

Ahos_0653

AMAN:

B6F84_06685

ABRI:

DFR85_08930

ASUL:

DFR86_05745

AAMB:

D1866_11040

ACIH:

HS5_20280

STEP:

IC006_1979

SMET:

RQ359_002246

PAI:

PAE1012

PIS:

Pisl_1207

PCL:

Pcal_0149

PAS:

Pars_0180

PYR:

P186_2438

POG:

Pogu_2299

TNE:

Tneu_0164

PYW:	PYWP30_00187

CMA:

Cmaq_1001

TTN:

TTX_2050

TUZ:

TUZN_1437

VDI:

Vdis_1766

VMO:

VMUT_0213

TPE:

Tpen_0607

THB:	N186_04380

TCB:	TCARB_1903

THEL:

IG193_04520

ASC:

ASAC_0904

ACIA:

SE86_05200

CLG:	Calag_0846

FFO:	FFONT_0456

KCR:

Kcr_1595

NMR:

Nmar_0314

NIR:	NSED_01515

NKR:	NKOR_01425

NID:	NPIRD3C_0716

NIN:	NADRNF5_1938

NIW:	Nisw_03345

NCL:	C5F47_01680

NOX:	C5F49_01675

NUE:	C5F50_02280

NIP:	NsoK4_07205

NZT:	NZOSNM25_001726

NCT:

NMSP_1394

NIC:	DSQ20_01830

NGA:	Ngar_c21610

NVN:	NVIE_008070

NEV:

NTE_02263

TAA:	NMY3_02132

NFN:	NFRAN_2921

NCV:

NCAV_1517

CSY:	CENSYa_1615

CSU:	CSUB_C0425

NBV:

T478_0246

TAH:	SU86_004395

NIU:	DSQ19_01720

NDV:

NDEV_0280

CCAI:

NAS2_0355

BARC:

AOA65_2113

BARB:

AOA66_1068

MARH:

Mia14_0599

FLT:	Sv326_0061

MIY:	Micr_00463

LOKI:

Lokiarch_22770

LOB:	NEF87_003597

PSYT:

DSAG12_01210 DSAG12_02985

» show all

Reference

1 [PMID:16621811]

Authors

Grochowski LL, Xu H, White RH

Title

Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate.

Journal

J Bacteriol 188:3192-8 (2006)
DOI:10.1128/JB.188.9.3192-3198.2006

Sequence

[mja:MJ_0044]

Reference

2 [PMID:10570138]

Authors

Lange BM, Croteau R

Title

Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step.

Journal

Proc Natl Acad Sci U S A 96:13714-9 (1999)
DOI:10.1073/pnas.96.24.13714

Reference

3 [PMID:19928876]

Authors

Chen M, Poulter CD

Title

Characterization of thermophilic archaeal isopentenyl phosphate kinases.

Journal

Biochemistry 49:207-17 (2010)
DOI:10.1021/bi9017957

Sequence

[mth:MTH_47] [tac:Ta0103]

Reference

4 [PMID:20402538]

Authors

Mabanglo MF, Schubert HL, Chen M, Hill CP, Poulter CD

Title

X-ray structures of isopentenyl phosphate kinase.

Journal

ACS Chem Biol 5:517-27 (2010)
DOI:10.1021/cb100032g

Sequence

[mth:MTH_47] [tac:Ta0103]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.4.26

IUBMB Enzyme Nomenclature:

2.7.4.26

ExPASy - ENZYME nomenclature database:

2.7.4.26

BRENDA, the Enzyme Database:

2.7.4.26

LinkDB

REACTION: R10093

Entry

R10093                      Reaction

Name

ATP:isopentenyl phosphate phosphotransferase

Definition

ATP + Isopentenyl phosphate <=> ADP + Isopentenyl diphosphate

Equation

C00002 + C20345 <=> C00008 + C00129

Reaction class

RC00002

C00002_C00008 C00129_C20345

Enzyme

2.7.4.26

Pathway

rn00900

Terpenoid backbone biosynthesis

rn01100

Metabolic pathways

rn01110

Biosynthesis of secondary metabolites

Module

M00849

C5 isoprenoid biosynthesis, mevalonate pathway, archaea

Brite

Enzymatic reactions [BR:br08201]
2. Transferase reactions
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.26
     R10093  ATP + Isopentenyl phosphate <=> ADP + Isopentenyl diphosphate

Orthology

K06981

isopentenyl phosphate kinase [EC:2.7.4.26]

Other DBs

RHEA:

33966

LinkDB

DBGET integrated database retrieval system