ORTHOLOGY: K07595
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Entry
K07595 KO
Symbol
MAFA
Name
transcription factor MAFA
Pathway
map04930
Type II diabetes mellitus
map04950
Maturity onset diabetes of the young
Disease
H02806
Insulinomatosis and diabetes mellitus syndrome
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K07595 MAFA; transcription factor MAFA
04950 Maturity onset diabetes of the young
K07595 MAFA; transcription factor MAFA
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors
K07595 MAFA; transcription factor MAFA
Transcription factors [BR:
ko03000
]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, Maf
K07595 MAFA; transcription factor MAFA
BRITE hierarchy
Genes
HSA:
389692
(MAFA)
PTR:
746440
(MAFA)
PPS:
117981593
(MAFA)
GGO:
101127290
(MAFA)
PON:
112134627
(MAFA)
PPYG:
129042556
(MAFA)
NLE:
115830653
(MAFA)
HMH:
116812735
(MAFA)
SSYN:
129485876
(MAFA)
MCC:
106999985
(MAFA)
MCF:
102126714
(MAFA)
MTHB:
126961024
MNI:
105488445
(MAFA)
CSAB:
103237565
(MAFA)
CATY:
105581200
(MAFA)
PANU:
101010868
(MAFA)
TGE:
112630451
(MAFA)
RRO:
104679788
(MAFA)
RBB:
108525284
(MAFA)
TFN:
117079666
(MAFA)
PTEH:
111553379
(MAFA)
CJC:
103788594
(MAFA)
CIMI:
108291273
(MAFA)
ANAN:
110568544
(MAFA)
MMUR:
105864790
(MAFA)
LCAT:
123644912
(MAFA)
PCOQ:
105813366
(MAFA)
OGA:
100952055
(MAFA)
MMU:
378435
(Mafa)
MCAL:
110311017
(Mafa)
MPAH:
110335176
(Mafa)
RNO:
366949
(Mafa)
MCOC:
116081233
(Mafa)
ANU:
117718972
(Mafa)
MUN:
110563114
(Mafa)
CGE:
113834505
MAUA:
101833897
(Mafa)
PROB:
127225659
(Mafa)
PLEU:
114684746
(Mafa)
MORG:
121461271
(Mafa)
MFOT:
126503429
AAMP:
119822957
(Mafa)
NGI:
103735294
(Mafa)
HGL:
101725333
(Mafa)
CPOC:
100733756
(Mafa)
CCAN:
109690814
(Mafa)
DORD:
105998970
(Mafa)
DSP:
122098923
(Mafa)
PLOP:
125360806
(Mafa)
NCAR:
124967476
OCU:
127489876
CFA:
100684427
(MAFA)
CLUD:
118353930
(MAFA)
VVP:
112911195
(MAFA)
VLG:
121498909
(MAFA)
NPO:
129502550
(MAFA)
AML:
105235374
(MAFA)
UMR:
121101709
(MAFA)
UAR:
123779291
(MAFA)
ELK:
111146724
LLV:
125099013
MNP:
132013314
(MAFA)
MLK:
131827773
(MAFA)
NVS:
122905495
(MAFA)
ORO:
101383866
(MAFA)
EJU:
114201060
(MAFA)
ZCA:
113938017
(MAFA)
MLX:
118015256
(MAFA)
NSU:
110579075
(MAFA)
FCA:
111558557
(MAFA)
PBG:
122495889
(MAFA)
PVIV:
125156572
(MAFA)
LRUF:
124507503
PPAD:
109258299
(MAFA)
AJU:
113600523
HHV:
120246483
(MAFA)
BTA:
618421
(MAFA)
BOM:
102266335
(MAFA)
BIU:
109568604
(MAFA)
BBUB:
102402400
(MAFA)
BBIS:
104985729
CHX:
108637537
(MAFA)
OAS:
106991336
(MAFA)
BTAX:
128059453
(MAFA)
ODA:
120878767
(MAFA)
CCAD:
122451452
(MAFA)
MBEZ:
129560237
(MAFA)
SSC:
100627724
(MAFA)
CFR:
116659811
(MAFA)
CDK:
105103887
(MAFA)
BMUS:
118883231
(MAFA)
LVE:
103087773
(MAFA)
OOR:
101282283
(MAFA)
DLE:
111165120
(MAFA)
PCAD:
112063016
(MAFA)
PSIU:
116742435
(MAFA)
NASI:
112397176
(MAFA)
ECB:
111775053
(MAFA)
EAI:
123290279
(MAFA)
MYB:
106725897
(MAFA)
MMYO:
118653176
(MAFA)
MDT:
132219816
(MAFA)
PKL:
118718615
(MAFA)
EFUS:
129147236
(MAFA)
MNA:
107542739
(MAFA)
DRO:
112315398
(MAFA)
SHON:
118988858
(MAFA)
AJM:
119064812
(MAFA)
PDIC:
114514570
(MAFA)
PHAS:
123832973
(MAFA)
MMF:
118643319
(MAFA)
PPAM:
129084363
(MAFA)
HAI:
109390837
(MAFA)
RFQ:
117033907
(MAFA)
PALE:
112480539
(MAFA)
PGIG:
120588783
(MAFA)
RAY:
107507887
(MAFA)
MJV:
118973345
(MAFA)
TOD:
119232640
(MAFA)
DNM:
101443589
(MAFA)
MDO:
100017161
(MAFA)
GAS:
123231991
(MAFA)
SHR:
116420711
(MAFA)
AFZ:
127544542
PCW:
110214453
(MAFA)
OAA:
100085015
(MAFA)
GGA:
395881
(MAFA)
PCOC:
116227796
(MAFA)
MGP:
100541507
(MAFA)
CJO:
107310640
(MAFA)
TPAI:
128091303
(MAFA)
LMUT:
125690483
(MAFA)
NMEL:
110393952
(MAFA)
APLA:
101801582
(MAFA)
CATA:
118257920
(MAFA)
AFUL:
116486489
(MAFA)
TGU:
100229012
(MAFA)
LSR:
110475164
(MAFA)
SCAN:
103815041
(MAFA)
PMOA:
120504656
(MAFA)
OTC:
121333394
(MAFA)
PRUF:
121349288
(MAFA)
GFR:
102040178
(MAFA)
FAB:
101820211
(MAFA)
OMA:
130249331
(MAFA)
PHI:
102101316
(MAFA)
PMAJ:
107214261
(MAFA)
CCAE:
111944290
(MAFA)
CCW:
109145326
(MAFA)
CBRC:
103623904
(MAFA)
ETL:
114071492
(MAFA)
ZLE:
135443432
(MAFA)
SVG:
106855606
(MAFA)
MMEA:
130584380
(MAFA)
HRT:
120753516
(MAFA)
SATI:
136372400
(MAFA)
FPG:
101918104
(MAFA)
FCH:
102051101
(MAFA)
CCRI:
104163295
(MAFA)
SHAB:
115605925
(MAFA)
TALA:
116960068
(MAFA)
ACHC:
115340703
(MAFA)
HLE:
104842117
(MAFA)
AGEN:
126049575
GCL:
127013333
CSTI:
104559781
LDI:
104350956
(MAFA)
DPUB:
104299739
(MAFA)
EGZ:
104127412
(MAFA)
NNI:
104020598
(MAFA)
AFOR:
103901308
(MAFA)
CLV:
102098406
(MAFA)
MUI:
104536946
PGUU:
104464535
(MAFA)
CUCA:
104063944
(MAFA)
OHA:
104335906
(MAFA)
ACAR:
104517914
(MAFA)
CPEA:
104392716
(MAFA)
104396352
(MAF)
CVF:
104284000
(MAFA)
RTD:
128905514
(MAFA)
AAM:
106491265
106491266
AROW:
112967917
(MAFA)
NPD:
112954000
(MAFA)
DNE:
112991288
(MAFA)
ASN:
102367893
(MAFA)
AMJ:
102558762
(MAFA)
CPOO:
109322546
(MAFA)
GGN:
109300002
(MAFA)
CMY:
119565487
(MAFA)
CCAY:
125632908
(MAFA)
DCC:
119851529
(MAFA)
CPIC:
101953602
(MAFA)
TST:
117873859
(MAFA)
CABI:
116815160
MRV:
120396634
(MAFA)
ASAO:
132775160
(MAFA)
PVT:
110089980
(MAFA)
SUND:
121928785
(MAFA)
PMUR:
107299036
(MAFA)
CTIG:
120319645
(MAFA)
TSR:
106545178
(MAFA)
PGUT:
117666916
(MAFA)
APRI:
131195781
(MAFA)
PTEX:
113451990
(MAFA)
NSS:
113432220
(MAFA)
PMUA:
114600184
PRAF:
128416991
(MAFA)
ZVI:
118089692
(MAFA)
HCG:
128325195
(MAFA)
GJA:
107116224
(MAFA)
STOW:
125425125
(MAFA)
EMC:
129333489
(MAFA)
XLA:
108695465
(mafa.S)
108719460
(mafa.L)
XTR:
613050
(mafa)
NPR:
108789039
(MAFA)
BBUF:
121001850
(MAFA)
BGAR:
122938135
(MAFA)
MUO:
115480867
(MAFA)
GSH:
117355402
(MAFA)
DRE:
100000492
(mafaa)
SRX:
107717140
107731633
SANH:
107692391
(mafa)
107704507
SGH:
107556987
107591187
CCAR:
109054961
109054964
CAUA:
113050525
113100444
CGIB:
127958984
128015636
PTET:
122346529
(mafaa)
LROH:
127167404
(mafaa)
OMC:
131541867
(mafaa)
PPRM:
120478260
(mafaa)
RKG:
130091292
(mafaa)
MAMB:
125273988
(mafaa)
CIDE:
127514928
CERY:
137011062
(mafaa)
MASI:
127445875
127448875
TROS:
130556763
(mafaa)
TDW:
130424712
(mafaa)
MANU:
129450964
(mafaa)
IPU:
108272265
(mafaa)
108275247
(nrl)
IFU:
128615023
(mafaa)
PHYP:
113529074
113538239
(mafa)
SMEO:
124388811
(mafaa)
124401487
(nrl)
TFD:
113648469
(mafaa)
113662407
(nrl)
TVC:
132844298
(mafaa)
TRN:
134316681
(mafaa)
134320824
(nrl)
AMEX:
103026745
(nrl)
103030760
(mafaa)
CMAO:
118801501
(mafaa)
118816281
(nrl)
EEE:
113587407
113587816
(mafa)
CHAR:
105895054
(nrl)
105907780
(mafaa)
TFS:
130528610
(nrl)
130529214
(mafaa)
TNG:
GSTEN00008337G001
LCO:
104934188
(mafa)
NCC:
104947091
104959349
(mafa)
TBEN:
117495129
(nrl)
117495253
(mafaa)
CGOB:
115007198
115007569
(mafa)
PGEO:
117445063
(nrl)
117445065
(mafaa)
GACU:
117555189
(nrl)
117560461
(mafaa)
EMAC:
134869256
(mafaa)
134869872
(nrl)
ELY:
117254332
(mafaa)
117254399
(nrl)
EFO:
125895334
(mafaa)
125895365
(nrl)
PLEP:
121941279
(mafaa)
121941330
(nrl)
SLUC:
116038214
(mafaa)
116058809
(nrl)
ECRA:
117949922
(mafaa)
117950163
(nrl)
ESP:
116695246
(mafa)
116695622
PFLV:
114561380
(mafa)
114561544
GAT:
120823847
(mafaa)
120824157
(nrl)
PPUG:
119216657
(nrl)
119217117
(mafaa)
AFB:
129094058
(nrl)
129094560
(mafaa)
CLUM:
117729791
(mafaa)
117729936
(nrl)
PSWI:
130193896
(mafaa)
130193938
(nrl)
MSAM:
119900246
(mafaa)
119901369
(nrl)
SCHU:
122877197
(nrl)
122877596
(mafaa)
CUD:
121511735
(nrl)
121511750
(mafaa)
ALAT:
119028052
119028231
(nrl)
119028737
(mafaa)
ASTR:
137599185
(nrl)
137599475
(mafaa)
MZE:
101476520
(mafa)
ONL:
100709735
(mafa)
OAU:
116329378
(mafaa)
116331171
(nrl)
OLA:
101163404
(mafa)
105353878
OML:
112137037
(nrl)
112150126
(mafaa)
CSAI:
133458282
(nrl)
133458681
(mafaa)
XMA:
102224719
102234178
(mafa)
XCO:
114151177
114151626
(mafa)
XHE:
116725947
116726509
(mafa)
PRET:
103463420
(mafa)
103463820
PFOR:
103129819
(mafa)
103137097
PLAI:
106937696
(mafa)
106963243
PMEI:
106914009
(mafa)
106919639
GAF:
122838039
(nrl)
122838864
(mafaa)
PPRL:
129370206
(nrl)
129376654
(mafaa)
CVG:
107091560
107099660
(mafa)
CTUL:
119780610
(nrl)
119787672
(mafaa)
GMU:
124873346
(mafaa)
124874355
(nrl)
NFU:
107393074
(mafa)
107393411
KMR:
108246640
(mafaa)
ALIM:
106536624
(mafa)
NWH:
119407627
(mafaa)
AOCE:
111568177
(mafa)
MCEP:
125008848
(nrl)
125010014
(mafaa)
CSEM:
103399897
(mafa)
POV:
109644715
(mafa)
SSEN:
122762454
(nrl)
122780486
(mafaa)
HHIP:
117759809
(mafaa)
117760551
(nrl)
HSP:
118120995
(mafaa)
118121135
(nrl)
PPLT:
128448132
(nrl)
128448273
(mafaa)
SMAU:
118318149
(mafaa)
118318435
(nrl)
LCF:
108879598
(mafaa)
SDU:
111227558
(mafa)
SLAL:
111648815
111671762
(mafa)
XGL:
120790768
(nrl)
120791359
(mafaa)
HCQ:
109516923
(mafa)
109532246
SSCV:
125972051
125994715
SBIA:
133503445
(mafaa)
133503455
(nrl)
PEE:
133406349
(nrl)
133406402
(mafaa)
PTAO:
133481313
(nrl)
133481355
(mafaa)
BPEC:
110165669
MALB:
109975016
(mafa)
BSPL:
114853472
(nrl)
129602914
(mafaa)
SJO:
128361414
(mafaa)
128361793
(nrl)
SASA:
106560283
106560405
(mafa)
106584064
106584133
STRU:
115158552
115158664
115192274
115193025
OTW:
112249292
112250264
112251150
112251333
(mafaa)
OMY:
110521774
110522778
110524567
110524677
OGO:
123996320
123997100
124037873
124038054
ONE:
115108545
115120240
115145149
115145373
OKI:
109884801
(mafa)
109897197
109898104
109901596
OKE:
118358711
118358829
118377374
(mafaa)
118395869
SALP:
111971608
111975295
111975990
SNH:
120051897
120052090
120054288
120054548
(mafaa)
CCLU:
121533862
(mafaa)
121533957
121540139
121540476
ELS:
105011854
105011957
(mafa)
SFM:
108923310
108937824
114911312
(mafa)
PKI:
111845861
111854581
111857140
111860743
AANG:
118225118
(nrl)
118226021
(mafaa)
118233470
118233984
118233985
118233986
LOC:
102696387
(mafa)
PSPA:
121305322
121312801
121314266
ARUT:
117399627
117435715
PSEX:
120529695
(mafaa)
LCM:
102345252
(MAFA)
CMK:
103183605
(mafaa)
RTP:
109920499
CPLA:
122549542
(mafaa)
HOC:
132815494
(mafaa)
LERI:
129696007
(mafaa)
BBEL:
109479388
TPRE:
106654637
DAM:
107048048
TCA:
658429
SOY:
115875454
NVL:
108557077
BMOR:
101742257
BMAN:
114244696
MSEX:
115447125
DPL:
KGM_215814
BANY:
112054295
MJU:
123868346
NIQ:
126781446
VCD:
124531299
MCIX:
123669166
PMAC:
106710686
PXU:
106127561
PRAP:
110991402
PBX:
123711792
PNAP:
125056942
ZCE:
119829951
CCRC:
123706100
LSIN:
126968977
AAGE:
121729575
HAW:
110371906
HZE:
124646343
TNL:
113506962
SLIU:
111352604
OFU:
114352036
ATRA:
106133586
GMW:
113522230
PXY:
119694445
PGW:
126366185
LGLY:
125227437
PCLA:
123747639
MNZ:
135214711
EAF:
111700715
CVS:
136980958
ABRU:
129963684
129973072
LJP:
135474800
LLON:
135496407
» show all
Taxonomy
UniProt
Reference
PMID:
12368292
Authors
Kataoka K, Han SI, Shioda S, Hirai M, Nishizawa M, Handa H
Title
MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene.
Journal
J Biol Chem 277:49903-10 (2002)
DOI:
10.1074/jbc.M206796200
Sequence
[hsa:
389692
]
LinkDB
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DBGET
integrated database retrieval system