KEGG ORTHOLOGY: K07996

ORTHOLOGY: K07996

Entry

K07996                      KO

Symbol

MMP16

Name

matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]

Pathway

map04928

Parathyroid hormone synthesis, secretion and action

map05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted)
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M10
   K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted)

Genes

HSA:	4325(MMP16)

PTR:	736322(MMP16)

PPS:	100988260(MMP16)

GGO:	101151831(MMP16)

PON:	100447086(MMP16)

PPYG:

129042547(MMP16)

NLE:	100583949(MMP16)

HMH:	116813390(MMP16)

SSYN:

129486582(MMP16)

MCC:	695120(MMP16)

MCF:	102138061(MMP16)

MTHB:

126961157

MNI:	105497291(MMP16)

CSAB:

103237094(MMP16)

CATY:

105572876(MMP16)

PANU:

101004470(MMP16)

TGE:	112630111(MMP16)

MLEU:

105550327(MMP16)

RRO:	104668895(MMP16)

RBB:	108545010(MMP16)

TFN:	117078981(MMP16)

PTEH:

111549690(MMP16)

CANG:

105508243(MMP16)

CJC:	100403505(MMP16)

SBQ:	101028671(MMP16)

CIMI:

108288711(MMP16)

ANAN:

105725874(MMP16)

CSYR:

103265327(MMP16)

MMUR:

105876562(MMP16)

LCAT:

123644727(MMP16)

ERUF:

138381767(MMP16)

PCOQ:

105809793(MMP16)

OGA:	100955486(MMP16)

MMU:	17389(Mmp16)

MCAL:

110292663(Mmp16)

MPAH:

110338693(Mmp16)

RNO:	65205(Mmp16)

MCOC:

116088038(Mmp16)

ANU:	117698774(Mmp16)

ASYL:

127680213(Mmp16)

MUN:	110556311(Mmp16)

CGE:	100762646(Mmp16)

MAUA:

101823970(Mmp16)

PROB:

127232373(Mmp16)

PLEU:

114694605(Mmp16)

PMAV:

102917779(Mmp16)

MORG:

121451566(Mmp16)

MFOT:

126486715

AAMP:

119826615(Mmp16)

CNL:	130887853(Mmp16)

NGI:	103748471(Mmp16)

HGL:	101711864(Mmp16)

CPOC:

100713166(Mmp16)

DORD:

105982768(Mmp16)

DSP:	122102391(Mmp16)

DMER:

138805836(Mmp16)

PLOP:

125360882(Mmp16)

NCAR:

124961852

MMMA:

125610509(Mmp16)

ITI:	101954739(Mmp16)

OCU:

100101605

OPI:	101519226(MMP16)

OCZ:	121166163(MMP16)

TUP:	102487906(MMP16)

GVR:	103593766(MMP16)

CFA:	487036(MMP16)

CLUD:

112650668(MMP16)

VVP:	112930857(MMP16)

VLG:	121499110(MMP16)

NPO:	129495755(MMP16)

AML:	100481342(MMP16)

UMR:	103661409(MMP16)

UAH:	113252967(MMP16)

UAR:	123797907(MMP16)

ELK:

111146675

LLV:

125098082

MPUF:

101684091(MMP16)

MNP:	132014138(MMP16)

MLK:	131826629(MMP16)

NVS:	122904463(MMP16)

ORO:	101379098(MMP16)

EJU:	114216012(MMP16)

ZCA:	113913228(MMP16)

MLX:	118014992(MMP16)

MANO:

123858918(MMP16)

NSU:	110578801(MMP16)

LWW:	102731970(MMP16)

FCA:	493663(MMP16)

PYU:	121042667(MMP16)

PCOO:

112859316(MMP16)

PBG:	122495567(MMP16)

PVIV:

125156619(MMP16)

LRUF:

124507449

LGF:	123585889(MMP16)

AJU:

106977251

PTG:	102972474(MMP16)

PPAD:

109269455(MMP16)

PUC:

125924565

PLEZ:

122210720(MMP16)

HHV:	120249037(MMP16)

CCRU:

144237590(MMP16)

BTA:	282886(MMP16)

BOM:	102269596(MMP16)

BIU:	109568565(MMP16)

BBUB:

102390402(MMP16)

BKE:	129627099(MMP16)

BBIS:

105004495(MMP16)

CHX:	102170337(MMP16)

OAS:	101116410(MMP16)

BTAX:

128059330(MMP16)

CSUM:

138088451(MMP16)

ODA:	120878519(MMP16)

CCAD:

122450974(MMP16)

MREE:

136144921(MMP16)

OVR:	110152137(MMP16)

MBEZ:

129559904(MMP16)

SSC:	100153257(MMP16)

CFR:	102509964(MMP16)

CBAI:

105066644(MMP16)

CDK:	105089491(MMP16)

VPC:	102530086(MMP16)

BACU:

103012033(MMP16)

BMUS:

118883245(MMP16)

LVE:

103087575

OOR:	101286903(MMP16)

LALB:

132507872(MMP16)

GMF:	115843341(MMP16)

DDP:	132440230(MMP16)

DLE:	111170862(MMP16)

PCAD:

102979024(MMP16)

PSIU:

116742127(MMP16)

PPHC:

136136819(MMP16)

NASI:

112391550(MMP16)

ECB:	100049862(MMP16)

EPZ:	103555232(MMP16)

EAI:	106847347(MMP16)

MYB:	102259167(MMP16)

MYD:	102764014(MMP16)

MMYO:

118670469(MMP16)

MLF:	102440636(MMP16)

MDT:	132220185(MMP16)

MYUM:

138992877(MMP16)

PKL:	118718489(MMP16)

EFUS:

103301860(MMP16)

MNA:	107526489(MMP16)

DRO:	112310311(MMP16)

SHON:

118989866(MMP16)

AJM:	119047348(MMP16)

PDIC:

114502032(MMP16)

PHAS:

123821091(MMP16)

MMF:	118631650(MMP16)

PPAM:

129087971(MMP16)

HAI:	109387587(MMP16)

RFQ:	117034013(MMP16)

PALE:

102880814(MMP16)

PGIG:

120585580(MMP16)

RAY:	107514931(MMP16)

MJV:	108394038(MMP16)

TOD:	119249590(MMP16)

SARA:

101548986(MMP16)

SFUM:

130020252(MMP16)

SETR:

126020867(MMP16)

LAV:	100662936(MMP16)

TMU:

101340946

ETF:	101659369(MMP16)

DNM:	101425499(MMP16)

MDO:	100021706(MMP16)

GAS:	123254921(MMP16)

SHR:	100920437(MMP16)

AFZ:

127544262

PCW:	110196728(MMP16)

TVP:	118835086(MMP16)

PBRV:

138160144(MMP16)

MLAO:

141497066(MMP16)

OAA:	100075102(MMP16)

TACU:

119927106(MMP16)

GGA:	396116(MMP16)

PCOC:

116227587(MMP16)

CJO:	107310392(MMP16)

TPAI:

128090772(MMP16)

LMUT:

125690742(MMP16)

NMEL:

110393672(MMP16)

APLA:

101801318(MMP16)

AACU:

137851262(MMP16)

OJA:	118161260(MMP16)

ACYG:

106030543(MMP16)

CATA:

118247895(MMP16)

AFUL:

116485847(MMP16)

TGU:	100225924(MMP16)

LSR:	110477422(MMP16)

VMC:	128807270(MMP16)

AIB:	137471285(MMP16)

SCAN:

103813384(MMP16)

PMOA:

120495785(MMP16)

OTC:	121340183(MMP16)

PRUF:

121351957(MMP16)

ATRC:

139587376(MMP16)

MATE:

118699016(MMP16)

GFR:	102039303(MMP16)

FAB:	101819544(MMP16)

OMA:	130250033(MMP16)

PHI:	102101377(MMP16)

PMAJ:

107200259(MMP16)

CCAE:

111924572(MMP16)

CCW:	104692767(MMP16)

CBRC:

103613440(MMP16)

ACOE:

138105967(MMP16)

ETL:	114064022(MMP16)

ZAB:	102063397(MMP16)

ZLE:	135444611(MMP16)

ACHL:

103811682

SVG:	106849859(MMP16)

MMEA:

130576430(MMP16)

HRT:	120752573(MMP16)

SATI:

136369965(MMP16)

CFAI:

136286975(MMP16)

CCIC:

134049995(MMP16)

FPG:	101914326(MMP16)

FCH:	102050130(MMP16)

CCRI:

104155684(MMP16)

SHAB:

115612440(MMP16)

ACUN:

113476586(MMP16)

ANOC:

141957373(MMP16)

SURA:

141949922(MMP16)

TALA:

104361489(MMP16)

ACHC:

115340514(MMP16)

HALD:

104313387 104314427

HLE:	104828370(MMP16)

AGEN:

126046578

HHAR:

128142195(MMP16)

BBUT:

142029157(MMP16)

GCL:

127013538

CSTI:

104553995

DPUB:

104297227(MMP16)

PPUS:

135181393(MMP16)

IIN:	128970245(MMP16)

AVIT:

104270564(MMP16)

BRHI:

104494592 104496559

EGZ:	104123323(MMP16)

NNI:	104016402(MMP16)

PCRI:

104027950(MMP16)

PCAO:

104047743(MMP16)

PARX:

142053549(MMP16)

PADL:

103925485(MMP16)

AFOR:

103896239(MMP16)

FGA:

104075563

CBOR:

142078659(MMP16)

GSTE:

104251597

CBOY:

140647532(MMP16)

MAME:

142406253(MMP16)

CLV:	102084076(MMP16)

CNIC:

135985089(MMP16)

MUI:	104535027(MMP16)

PGUU:

104464160(MMP16)

PLET:

104619798

CMAC:

104483833

CUCA:

104056758(MMP16)

GAME:

129203102(MMP16)

OHA:	104339432(MMP16)

ACAR:

104520497

CPEA:

104396564(MMP16)

CVF:	104292470(MMP16)

RTD:	128905363(MMP16)

CRID:

134512100(MMP16)

LMIC:

141739668(MMP16)

NARQ:

141462818(MMP16)

AAM:	106496286(MMP16)

AROW:

112973037(MMP16)

NPD:	112960328(MMP16)

TGT:	104575110(MMP16)

DNE:	112983018(MMP16)

SCAM:

104143939(MMP16)

ASN:	102377798(MMP16)

AMJ:	102569337(MMP16)

CPOO:

109320168(MMP16)

GGN:	109305014(MMP16)

PSS:	102447881(MMP16)

CIZ:	142009237(MMP16)

CMY:	102940575(MMP16)

CCAY:

125632631(MMP16)

LKP:	140906540(MMP16)

NDS:	141982252(MMP16)

DCC:	119851810(MMP16)

CPIC:

101935560(MMP16)

TST:	117873639(MMP16)

EOB:	135874136(MMP16)

CABI:

116838974(MMP16)

MRV:	120399314(MMP16)

ACS:	100551730(mmp16)

ASAO:

132774965(MMP16)

PVT:	110085125(MMP16)

SUND:

121929588(MMP16)

PMUR:

107284965(MMP16)

CTIG:

120313357(MMP16)

TSR:	106553495(MMP16)

PGUT:

117668483(MMP16)

PCAE:

139315722(MMP16)

APRI:

131195863(MMP16)

PTEX:

113439833(MMP16)

NSS:	113426712(MMP16)

VKO:	123020381(MMP16)

PMUA:

114600451(MMP16)

PRAF:

128417278(MMP16)

ZVI:	118089914(MMP16)

HCG:	128323516(MMP16)

GJA:	107114051(MMP16)

STOW:

125439296(MMP16)

EMC:	129333356(MMP16)

XLA:	108695375(mmp16.S) 443562(mmp16.L)

XTR:	548746(mmp16)

RTEM:

120941265(MMP16)

ACAT:

141145334(MMP16)

PADS:

140330657(MMP16)

BBUF:

121000691(MMP16)

BGAR:

122938584(MMP16)

DTC:	141053172(MMP16)

HSQ:	130274227(MMP16)

PCOB:

134928382(MMP16)

PWL:	138282645(MMP16)

MUO:	115478724(MMP16)

GSH:	117355188(MMP16)

DRE:	564419(mmp16a) 572034(mmp16b)

SRX:	107712777 107747512

SANH:

107657744 107677151 107681831 107691105

SGH:	107552291 107555402 107566471

CCAR:

109050205 109066121 109069077 109095054(mmp16b)

CAUA:

113042549 113045982 113081284 113114403

CGIB:

127946460 127951007 128013644 128022351

PTET:

122325049 122325182 122330065

LROH:

127153650(mmp16b) 127155397

GRF:	141300896 141344222(mmp16b)

OMC:	131530833(mmp16b) 131532905

PPRM:

120470342(mmp16b) 120488227

RKG:	130084082 130097603(mmp16b)

MAMB:

125251503(mmp16b) 125257647

CIDE:

127503975 127506131

CERY:

137002706(mmp16b) 137013944

MASI:

127431808 127434463 127441582 127442012

TROS:

130546848 130554879(mmp16b)

TDW:	130413281 130418250(mmp16b)

MANU:

129426018 129442583(mmp16b)

PDAB:

135740307 135750860(mmp16b)

IPU:	108269081 108280576(mmp16b)

IFU:	128611638 128624303(mmp16b)

PHYP:

113533991(mmp16) 113546404

SMEO:

124384416 124403456(mmp16b)

TFD:	113644451 113655513(mmp16b)

TVC:	132845799 132859941(mmp16b)

CGAR:

128513499(mmp16b) 128520336

NGRA:

132871359(mmp16b) 132886907

TRN:	134302857(mmp16b) 134309946

AMEX:

103028887(mmp16b) 103046458

CMAO:

118797337(mmp16b) 118818605

EEE:	113580839(mmp16) 113591904

CHAR:

105897236 105900544(mmp16b)

SPIL:

134065661 134073151(mmp16b)

ASAD:

121688247 121722880(mmp16b)

TRU:	101069093 101070441

TFS:	130513438 130539497(mmp16b)

TNG:	GSTEN00027645G001

LCO:	104917710 104918159(mmp16)

NCC:	104941936(mmp16)

TBEN:

117484110 117488313(mmp16b)

CGOB:

115022918 115025331

PGEO:

117462998(mmp16b) 117465673

GACU:

117543653 117558496(mmp16b)

EMAC:

134858051 134866627(mmp16b)

ELY:	117264782 117272332(mmp16b)

EFO:	125882205 125902271(mmp16b)

PLEP:

121951440(mmp16b) 121960736

SLUC:

116046210(mmp16b) 116046309

ECRA:

117937804 117954258(mmp16b)

ESP:	116672081 116699230

PFLV:

114549465 114565657

GAT:	120811661 120816451(mmp16b)

PPUG:

119198716

AFB:	129088839(mmp16b) 129110784

CLUM:

117746631(mmp16b) 117749819

PSWI:

130206374

CANA:

137780109(mmp16b) 137788555

CVE:	137892803(mmp16b)

MSAM:

119901960(mmp16b) 119907420

SCHU:

122866701 122887111(mmp16b)

EARM:

139295978(mmp16b) 139304671

CUD:	121519605(mmp16b) 121527264

SPUL:

138595658 138611195(mmp16b)

LMIX:

132979284(mmp16b) 132994050

HTC:	141804147(mmp16b) 141807354(mmp16a)

ALAT:

119008904 119011884(mmp16b)

ASTR:

137587631 137612887(mmp16b)

PKLU:

139213848(mmp16b) 139221020

MZE:	101478094(mmp16a) 101483831(mmp16b)

ONL:	100694913 100707316

OAU:	116315311(mmp16b) 116335787

OLA:	100125424(mmp16) 101156684

OML:	112147307(mmp16b) 112151285

CSAI:

133423710 133452836(mmp16b)

XMA:	102226480 102230808(mmp16)

XCO:	114136784(mmp16) 114146864

XHE:	116711739(mmp16) 116721712

PRET:

103479866 103482305(mmp16)

PFOR:

103135726 103147991

PLAI:

106958659 106958905

PMEI:

106909070 106924541(mmp16)

GAF:	122824055 122841049(mmp16b)

PPRL:

129362261(mmp16b) 129364722

CVG:	107081663 107095249(mmp16)

CTUL:

119794181(mmp16b) 119795984

GMU:	124857944 124869447(mmp16b)

NFU:	107382684 107383831

KMR:	108241715(mmp16b) 108245428

ALIM:

106533018 106535468

NWH:

119426686

AOCE:

111573604(mmp16b) 111587077

EJA:	138199375 138203075(mmp16b)

BFRE:

138617325(mmp16b) 138620584

MCEP:

124995706 125011152(mmp16b)

CSEM:

103377029 103396352

POV:	109629527 109637175

SSEN:

122775300 122778862(mmp16b)

SSOE:

131463816 131468280(mmp16b)

HHIP:

117753898 117777713(mmp16b)

HSP:	118098405 118117202(mmp16b)

PPLT:

128425982 128454627(mmp16b)

SMAU:

118291229 118311542(mmp16b)

LCF:	108883328(mmp16b) 108898232

SDU:	111228255(mmp16) 111231126

SLAL:

111648214(mmp16) 111652949

XGL:	120790153 120799104(mmp16b)

HCQ:	109514234 109521381

SSCV:

125984755(mmp16b) 125985817

SBIA:

133492775 133511127(mmp16b)

PEE:	133396541 133411362(mmp16b)

PTAO:

133470331 133488959(mmp16b)

BPEC:

110165362 110170443

ENY:	140356127(mmp16b) 140364411

MALB:

109955449(mmp16)

BSPL:

114844698(mmp16b) 114853351

SJO:	128368536(mmp16b) 128382208

SSCO:

133990960(mmp16b) 134001912

TTY:	137172906 137194348(mmp16b)

GMH:	115537083 115548816

SASA:

106569311 106578526(mmp16) 106600425

STRU:

115148898 115157225 115169554

OTW:	112215564 112226766 112260665(mmp16b)

OMY:	110508549 110530511(mmp16b) 110535521

OGO:	123991163 124009892(mmp16b) 124041722

ONE:	115102927 115105078(mmp16) 115114593

OKI:	109872132 109875080 109909992(mmp16)

OKE:	118361593 118394835 118402519(mmp16b)

OMM:	135512195(mmp16b) 135522661 135558869

OCLA:

139376203 139387223 139420392

SALP:

111956299 111973050(mmp16) 111979431

SNH:	120020249 120028086 120055605(mmp16b)

SFON:

129813768(mmp16b) 129822870 129824194

CCLU:

121535558 121549929 121581069

ELS:	105020005 105027114(mmp16)

OEP:	134036719(mmp16b)

SFM:	108927733(mmp16) 108938325

PKI:	111834037 111846217

AANG:

118225469 118234709

AROT:

135253885 135260755

CCOG:

133126729 133137387(mmp16b)

LOC:	102687027(mmp16)

PSPA:

121312706 121314157

ARUT:

117394770 117400381

PSEX:

120530116(mmp16b)

LCM:	102367208(MMP16)

CMK:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

LERI:

HAKA:

PMRN:

LRJ:

BFO:

BBEL:

CIN:

CLEP:

LVG:

AJJ:	139981134 139981384 139982062

AAMU:

139938565 139939040 139939070 139944268

AFIL:

AJC:

LSAX:

AIRR:

MCAZ:

MFOO:

Reference

PMID:18060181

Authors

Amalinei C, Caruntu ID, Balan RA

Title

Biology of metalloproteinases.

Journal

Rom J Morphol Embryol 48:323-34 (2007)

Reference

PMID:7559440

Authors

Takino T, Sato H, Shinagawa A, Seiki M

Title

Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.

Journal

J Biol Chem 270:23013-20 (1995)
DOI:10.1074/jbc.270.39.23013

Sequence

[hsa:4325]

LinkDB

DBGET integrated database retrieval system