| Entry |
|
| Symbol |
SCP2, SCPX
|
| Name |
|
| Pathway |
| map01040 | Biosynthesis of unsaturated fatty acids |
|
| Module |
| M00104 | Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate |
| M00861 | beta-Oxidation, peroxisome, VLCFA |
| M00862 | beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA |
|
| Reaction |
| R03719 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase |
| R04811 | propanoyl-CoA:acetyl-CoA C-acyltransferase |
| R07937 | (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA:acetyl-CoA C-acyltransferase |
| R07953 | (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA:acetyl-CoA C-acyltransferase |
|
| Disease |
| H00407 | Peroxisomal beta-oxidation enzyme deficiency |
| H00874 | Leukoencephalopathy with dystonia and motor neuropathy |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
K08764 SCP2, SCPX; sterol carrier protein 2
01040 Biosynthesis of unsaturated fatty acids
K08764 SCP2, SCPX; sterol carrier protein 2
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
K08764 SCP2, SCPX; sterol carrier protein 2
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
K08764 SCP2, SCPX; sterol carrier protein 2
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.176 propanoyl-CoA C-acyltransferase
K08764 SCP2, SCPX; sterol carrier protein 2
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Russell DW |
| Title |
The enzymes, regulation, and genetics of bile acid synthesis. |
| Journal |
|
| Reference |
|
| Authors |
Stanley WA, Filipp FV, Kursula P, Schuller N, Erdmann R, Schliebs W, Sattler M, Wilmanns M |
| Title |
Recognition of a functional peroxisome type 1 target by the dynamic import receptor pex5p. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Ferdinandusse S, Denis S, Mooijer PA, Zhang Z, Reddy JK, Spector AA, Wanders RJ |
| Title |
Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid. |
| Journal |
J Lipid Res 42:1987-95 (2001) |
| LinkDB |
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