KEGG ORTHOLOGY: K10324

ORTHOLOGY: K10324

Entry

K10324                      KO

Symbol

ASB2

Name

ankyrin repeat and SOCS box protein 2

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10324  ASB2; ankyrin repeat and SOCS box protein 2
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     K10324  ASB2; ankyrin repeat and SOCS box protein 2

Genes

HSA:	51676(ASB2)

PTR:	467538(ASB2)

PPS:	100987101(ASB2)

GGO:	101142725(ASB2)

PON:	100451651(ASB2)

PPYG:

129012115(ASB2)

NLE:	100582010(ASB2)

HMH:	116484875(ASB2)

SSYN:

129487495(ASB2)

MCC:	699882(ASB2)

MCF:	102127434(ASB2)

MTHB:

126959651

MNI:	105467513(ASB2)

CSAB:

103229596(ASB2)

CATY:

105596609(ASB2)

PANU:

100999099(ASB2)

TGE:	112628631(ASB2)

MLEU:

105547933(ASB2)

RRO:	104679061(ASB2)

RBB:	108519137(ASB2)

TFN:	117071494(ASB2)

PTEH:

111538251(ASB2)

CANG:

105518521(ASB2)

CJC:	100385735(ASB2)

SBQ:	101034374(ASB2)

CIMI:

108316866(ASB2)

ANAN:

105717797(ASB2)

MMUR:

105856753(ASB2)

LCAT:

123645070(ASB2)

PCOQ:

105819041(ASB2)

OGA:	100957930(ASB2)

MMU:	65256(Asb2)

MCAL:

110306977(Asb2)

MPAH:

110324513(Asb2)

RNO:	299266(Asb2)

MCOC:

116080886(Asb2)

ANU:	117697489(Asb2)

ASYL:

127687001(Asb2)

MUN:	110555942(Asb2)

CGE:	100764972(Asb2)

MAUA:

101842412(Asb2)

PROB:

127231096(Asb2)

PLEU:

114706042(Asb2)

MORG:

121434361(Asb2)

MFOT:

126507284

AAMP:

119819637(Asb2)

NGI:	103724582(Asb2)

HGL:	101706168(Asb2)

CPOC:

100735515(Asb2)

CCAN:

109699653(Asb2)

DORD:

105983405(Asb2)

DSP:	122118878(Asb2)

PLOP:

125363253(Asb2)

NCAR:

124975919

MMMA:

107150118(Asb2)

ITI:	101970510(Asb2)

OCU:	100345020 127484614

OPI:	101531250(ASB2)

TUP:	102477145(ASB2)

GVR:	103602636(ASB2)

CFA:	490836(ASB2)

CLUD:

112656990(ASB2)

VVP:	112907340(ASB2)

VLG:	121492972(ASB2)

NPO:	129496240(ASB2)

AML:	100483615(ASB2)

UMR:	103673743(ASB2)

UAH:	113267322(ASB2)

UAR:	123803943(ASB2)

ELK:

111148565

LLV:

125104340

MPUF:

101679169(ASB2)

MNP:	132000220(ASB2)

MLK:	131836937(ASB2)

NVS:	122893294(ASB2)

ORO:	101363760(ASB2)

EJU:	114205316(ASB2)

ZCA:	113909462(ASB2)

MLX:	118002506(ASB2)

NSU:	110571532(ASB2)

LWW:	102735623(ASB2)

FCA:	101101572(ASB2)

PYU:	121032230(ASB2)

PCOO:

112855866(ASB2)

PBG:	122469479(ASB2)

PVIV:

125167795(ASB2)

LRUF:

124512550

LGF:	123584243(ASB2)

AJU:

106977442

PTG:	102950539(ASB2)

PPAD:

109274498(ASB2)

PUC:

125909210

PLEZ:

122223085(ASB2)

HHV:	120220224(ASB2)

BTA:	539244(ASB2)

BOM:	102282635(ASB2)

BIU:	109575234(ASB2)

BBUB:

102405510(ASB2)

BBIS:

104985869(ASB2)

CHX:	102184287(ASB2)

OAS:	101114059(ASB2)

BTAX:

128066539(ASB2)

CSUM:

138095503(ASB2)

ODA:	120874970(ASB2)

CCAD:

122455020(ASB2)

MREE:

136147343(ASB2)

OVR:	110126331(ASB2)

MBEZ:

129550607(ASB2)

SSC:	100153068(ASB2)

CFR:	102518669(ASB2)

CBAI:

105079884(ASB2)

CDK:	105095747(ASB2)

VPC:	102532616(ASB2)

BACU:

103008182(ASB2)

BMUS:

118890739(ASB2)

LVE:	103079253(ASB2)

OOR:	101272392(ASB2)

LALB:

132529541(ASB2)

DLE:	111176132(ASB2)

PCAD:

102980536(ASB2)

PSIU:

116750014(ASB2)

NASI:

112408286(ASB2)

ECB:	100064381(ASB2)

EPZ:	103564843(ASB2)

EAI:	106825379(ASB2)

MYB:	102247979(ASB2)

MYD:	102770293(ASB2)

MMYO:

118659649(ASB2)

MLF:	102429329(ASB2)

MDT:	132230160(ASB2)

MYUM:

139009234 139010187

PKL:	118704237(ASB2)

EFUS:

103302890(ASB2)

MNA:	107536659(ASB2)

DRO:	112311771(ASB2)

SHON:

118976709(ASB2)

AJM:	119037918(ASB2)

PDIC:

114492702(ASB2)

PHAS:

123808231(ASB2)

MMF:	118632211(ASB2)

PPAM:

129065809(ASB2)

HAI:	109382754(ASB2)

RFQ:	117023902(ASB2)

PALE:

102878464(ASB2)

PGIG:

120619641(ASB2)

PVP:	105305162(ASB2)

RAY:	107511256(ASB2)

MJV:	108407430(ASB2)

TOD:	119239440(ASB2)

SARA:

101551834(ASB2)

SFUM:

130041769(ASB2)

SETR:

126003635(ASB2)

LAV:	100670512(ASB2)

TMU:

101344217

ETF:	101660420(ASB2)

DNM:	101441341(ASB2)

MDO:	100014676(ASB2)

GAS:	123235903(ASB2)

SHR:	100927977(ASB2)

AFZ:

127549396

PCW:	110217729(ASB2)

TVP:	118828844(ASB2)

PBRV:

138159691(ASB2)

OAA:	100080199(ASB2)

TACU:

119928390(ASB2)

GGA:	423428(ASB2)

PCOC:

116228886(ASB2)

MGP:	100544084(ASB2)

CJO:	107315250(ASB2)

TPAI:

128085817(ASB2)

LMUT:

125694443(ASB2)

NMEL:

110401772(ASB2)

APLA:

101802678(ASB2)

ACYG:

106036434(ASB2)

CATA:

118244541(ASB2)

AFUL:

116489319(ASB2)

TGU:	100227715(ASB2)

LSR:	110476407(ASB2)

SCAN:

103826456(ASB2)

PMOA:

120503862(ASB2)

OTC:	121337511(ASB2)

PRUF:

121356006(ASB2)

ATRC:

139589813(ASB2)

GFR:	102040083(ASB2)

FAB:	101807888(ASB2)

OMA:	130254228(ASB2)

PHI:	102104570(ASB2)

PMAJ:

107206161(ASB2)

CCAE:

111929859(ASB2)

CCW:	104686206(ASB2)

CBRC:

103612129(ASB2)

ACOE:

138111796(ASB2)

ETL:	114060634(ASB2)

ZAB:	102067003(ASB2)

ZLE:	135448579(ASB2)

ACHL:

103809516(ASB2)

SVG:	106858065(ASB2)

MMEA:

130576185(ASB2)

HRT:	120754508(ASB2)

SATI:

136362892(ASB2)

CCIC:

134045576(ASB2)

FPG:	101915805(ASB2)

FCH:	102047688(ASB2)

CCRI:

104158347(ASB2)

NNT:	104406340(ASB2)

SHAB:

115606685(ASB2)

ACUN:

113480861(ASB2)

TALA:

104363636(ASB2)

ACHC:

115336996(ASB2)

HALD:

104325531(ASB2)

HLE:	104841884(ASB2)

AGEN:

126050641

HHAR:

128139918(ASB2)

GCL:

127017328

CSTI:

104554688(ASB2)

LDI:	104348676(ASB2)

MNB:	103775435(ASB2)

DPUB:

104306327(ASB2)

PPUS:

135174828(ASB2)

AVIT:

104275808(ASB2)

BRHI:

104501642(ASB2)

EGZ:	104135334(ASB2)

NNI:	104014793(ASB2)

PCRI:

104032827

PCAO:

104047732(ASB2)

PADL:

103923931(ASB2)

AFOR:

103900176(ASB2)

FGA:	104080571(ASB2)

GSTE:

104260358

CBOY:

140653519(ASB2)

CLV:	102092653(ASB2)

MUI:	104546744(ASB2)

PGUU:

104463680(ASB2)

PLET:

104628533(ASB2)

EHS:	104516954(ASB2)

CMAC:

104477155(ASB2)

CUCA:

104057765(ASB2)

TEO:	104379352(ASB2)

BREG:

104633088(ASB2)

OHA:	104331497(ASB2)

ACAR:

104529898(ASB2)

CPEA:

104394201(ASB2)

CVF:	104295662(ASB2)

RTD:	128909299(ASB2)

CRID:

134514627(ASB2)

AAM:	106482940(ASB2)

AROW:

112972718(ASB2)

NPD:	112953693(ASB2)

TGT:	104565721(ASB2)

DNE:	112990105(ASB2)

SCAM:

104153766(ASB2)

ASN:	102376543(ASB2)

AMJ:	102577266(ASB2)

CPOO:

109321714(ASB2)

GGN:	109298498(ASB2)

PSS:	102454178(ASB2)

CMY:	102932893(ASB2)

CCAY:

125638500(ASB2)

DCC:	119857573(ASB2)

CPIC:

101952712(ASB2)

TST:	117876173(ASB2)

CABI:

116820252(ASB2)

MRV:	120404446(ASB2)

ACS:	100560418(asb2)

ASAO:

132762981(ASB2)

PVT:	110083643(ASB2)

SUND:

121915862(ASB2)

PBI:	103048871(ASB2)

PMUR:

107287215(ASB2)

CTIG:

120318366(ASB2)

TSR:	106543127(ASB2)

PGUT:

117665942(ASB2)

APRI:

131187876(ASB2)

PTEX:

113444598(ASB2)

NSS:	113419686(ASB2)

VKO:	123026712(ASB2)

PMUA:

114590651(ASB2)

PRAF:

128407629(ASB2)

ZVI:	118080886(ASB2)

HCG:	128328903(ASB2)

STOW:

125426862(ASB2)

EMC:	129323345(ASB2)

XLA:	108698729(asb2.L) 108699813(asb2.S)

XTR:	100490014(asb2)

NPR:	108789404(ASB2)

BBUF:

120981417(ASB2)

BGAR:

122921230(ASB2)

PWL:	138260090(ASB2)

MUO:	115478086(ASB2)

GSH:	117364314(ASB2)

DRE:	567986(asb2a.1)

SRX:	107711632 107711656 107721379 107721380 107749538(asb2) 107751298

SANH:

107659189 107659190 107665366 107665367 107677683 107687599

SGH:	107573589 107575235(asb2) 107583790 107583801 107602264 107602948

CCAR:

109074134 109101129(asb2b) 109110620 122140945

CAUA:

113060413 113062899 113062900 113063141 113063142 113077979 113116924 113120905

CGIB:

127938999 127983602

PTET:

122324303(asb2a.1)

LROH:

127182499(asb2a.1)

OMC:	131526701(asb2a.1)

PPRM:

120462447(asb2b) 120494018(asb2a.1)

RKG:	130091855(asb2a.1)

MAMB:

125268093(asb2b) 125277931(asb2a.1)

CIDE:

127502846

CERY:

137018985(asb2a.1)

MASI:

127409849 127416277

TROS:

130566345(asb2a.1)

TDW:	130434498(asb2a.1)

MANU:

129429426(asb2a.1)

PDAB:

135737972 135738819

IPU:	108257617 108258097(asb2a.1) 108258099 108270465(asb2b)

IFU:	128601021 128601027(asb2a.1) 128612366(asb2b)

PHYP:

113538718 113547653 113547661 113547694

SMEO:

124377304(asb2a.1) 124377444 124377445 124390523(asb2b)

TFD:	113643327(asb2a.1) 113643333(asb2a.2) 113659723(asb2b)

TVC:	132843026(asb2a.1) 132852420(asb2b)

CGAR:

128515136 128515188 128535396(asb2b)

NGRA:

132883102(asb2a.1) 132893963(asb2b)

TRN:	134320760(asb2a.1) 134320762 134324853(asb2b)

AMEX:

103041704(asb2a.1) 103042002(asb2b) 103042834(asb2a.2) 103047227

CMAO:

118815671(asb2a.1) 118816176 118816177 118823709(asb2b)

EEE:	113570488 113570562 113570564(asb2) 113578387

CHAR:

105896990 105897096

SPIL:

134098341 134098406

TRU:	101065538 101074622

TFS:	130516050 130539671

TNG:	GSTEN00008427G001 GSTEN00032257G001

LCO:	104921401 104934437

NCC:	104941863(asb2) 104948602

TBEN:

117474941 117483654

CGOB:

115004612 115004630 115027045

PGEO:

117468102

GACU:

117537910 117537914

EMAC:

134863205 134863206 134880968

ELY:	117267208 117270536 117271109

EFO:	125896707(asb2a.2) 125896708 125901323

PLEP:

121953790 121955586

SLUC:

116035826 116061024(asb2a.1) 116061046(asb2a.2)

ECRA:

117936043 117941260 117941264

ESP:	116670139(asb2) 116678681

PFLV:

114547388 114572905 114573241

GAT:	120814272(asb2a.1) 120814273 120833373

PPUG:

119194671 119195263(asb2a.1) 119228060

AFB:	129103565 129107517(asb2a.1) 129107518

CLUM:

117727691 117751461

PSWI:

130202009

CANA:

137782466 137787571

CVE:	137870878 137870879 137884540

MSAM:

119909061(asb2a.1) 119909063(asb2a.2) 119909939(asb2b)

SCHU:

122862254 122862905 122863338(asb2a.1)

CUD:	121521078 121526203

SPUL:

138583591 138591812

LMIX:

132985369 132985432 132993140

ALAT:

119004622 119012760

ASTR:

137610947 137613317

MZE:	101470851 101482600

ONL:	100699503(asb2) 100706241 100706505

OAU:	116332860 116332933 116334689

OLA:	101157753 101169259

OML:	112143466 112157620

CSAI:

133462683 133464729 133464731

XMA:	102218199 102218460 102230722

XCO:	114133937 114158960 114158962

XHE:	116708934 116733902 116733910

PRET:

103457067 103457069 103458936

PFOR:

103130366 103130378 103138795

PLAI:

106935555 106935556 106963339

PMEI:

106905627(asb2) 106909418

GAF:	122825311(asb2a.1) 122825312 122845864

PPRL:

129353678(asb2a.1) 129374717

CVG:	107098153 107098161 107099109

CTUL:

119771447 119796686 119796704(asb2a.1)

GMU:	124881539(asb2a.1) 124882180(asb2a.2) 124885063

NFU:	107377954 107377955 107392339(asb2)

KMR:	108233756 108249100(asb2a.1) 108249102

ALIM:

106521117 106527687 106527688

NWH:	119418406 119426983

AOCE:

111574964 111578902 129350181

EJA:	138199905 138212350 138212357

BFRE:

138630493(asb2b) 138636825 138636828(asb2a.1)

MCEP:

124998950 125024242

CSEM:

103377362(asb2) 103381371

POV:	109627934(asb2) 109647441

SSEN:

122782511 122783875

SSOE:

131443290 131444629

HHIP:

117755609 117758716

HSP:	118104009 118116700

PPLT:

128451553 128460341

SMAU:

118286634 118289837

LCF:	108890052(asb2a.1) 108890054

SDU:	111225547 111231707 111231708

SLAL:

111645959 111645969 111662435 111663118

XGL:	120788864 120789233 120795112

HCQ:	109516062(asb2) 109531760

SSCV:

125980856 125990487

SBIA:

133512871

PEE:	133413146(asb2a.1)

PTAO:

133468050 133488110

BPEC:

110155466(asb2) 110158181

ENY:	140370541 140381446

MALB:

109955032 109974436 109974478

BSPL:

114848086 114849405

SJO:	128375083 128377438

SSCO:

133976750 133977147 134000980

GMH:	115534879 115543968(asb2)

SASA:

106571695 106571696 106571697 106596550 106607652 106607987 106607989

STRU:

115172561 115174396 115174645(asb2) 115174647 115178295 115178418 115195227

OTW:	112233212 112244734 112250438(asb2a.2) 112250439 112250440

OMY:	110497867 110521979 110522378 110522379 110529735(asb2a.2) 110529736 110529738 118964302

OGO:	123990870(asb2a.1) 123991656(asb2a.2) 123991657 123994928 123995546 123995812 124001830

ONE:	115107874 115107875 115107876 115139278 115139583 115146188

OKI:	109866340 109866530 109894466 109900854 109900855(asb2) 109901388

OKE:	118362539 118369082 118386730 118387050 118397788 118398533(asb2a.1) 118398534

OMM:	135505844 135505845 135505847 135508168 135557163 135557296

OCLA:

139374255 139406934 139407259 139407260 139415241 139415242

SALP:

111954120 111954176 111954647 111968689 111972895 111972896 112068369

SNH:	120019329 120019330 120019613 120023960 120023961 120023962 120060004

CCLU:

121539320 121544869 121548772 121548773 121549150 121560549 121560552 121565041

ELS:	105015596 105017663 105017664

OEP:	134024749 134025489 134026823

SFM:	108919365(asb2) 108942630

PKI:	111838315 111838930(asb2) 111843436 111861015

AANG:

118219634 118229218 118230430

AROT:

135249830 135257123 135257125

CCOG:

133107458 133129466 133129509

LOC:	102697298(asb2)

PSPA:

121324548 121329971

ARUT:

117422232 117425200

PSEX:

120518297(asb2a.1)

LCM:	102358372(ASB2)

CMK:	103185407(asb2a.1)

RTP:	109918509(asb2a.1)

CPLA:

122553430(asb2a.1)

HOC:	132817980(asb2a.1)

LERI:

129699968(asb2a.1)

PMRN:

116939659 116939662 116947901 116948400

LRJ:	133341256 133346932 133347318 133352747

BFO:	118412294 118421131

CIN:	100175765 100184228

SCLV:

LPIC:

HHAL:

ESN:

PMAX:

MMER:

NVE:

ATEN:

ADF:

AMIL:

Reference

PMID:15590664

Authors

Heuze ML, Guibal FC, Banks CA, Conaway JW, Conaway RC, Cayre YE, Benecke A, Lutz PG

Title

ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.

Journal

J Biol Chem 280:5468-74 (2005)
DOI:10.1074/jbc.M413040200

Sequence

[hsa:51676]

LinkDB

DBGET integrated database retrieval system