| Entry |
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| Symbol |
novL, cloL, couL
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| Name |
8-demethylnovobiocic acid synthase [EC: 6.3.1.15]
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| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
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| Reaction |
| R10453 | 3-dimethylallyl-4-hydroxybenzoate:3-amino-4,7-dihydroxycoumarin ligase (AMP-forming) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
K12709 novL, cloL, couL; 8-demethylnovobiocic acid synthase
Enzymes [BR:ko01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.1 Acid-D-ammonia (or amine) ligases (amide synthases)
6.3.1.15 8-demethylnovobiocic acid synthase
K12709 novL, cloL, couL; 8-demethylnovobiocic acid synthase
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| Genes |
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| Reference |
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| Authors |
Steffensky M, Muhlenweg A, Wang ZX, Li SM, Heide L |
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| Title |
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Pojer F, Li SM, Heide L. |
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| Title |
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Schmutz E, Steffensky M, Schmidt J, Porzel A, Li SM, Heide L. |
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| Title |
An unusual amide synthetase (CouL) from the coumermycin A1 biosynthetic gene cluster from Streptomyces rishiriensis DSM 40489. |
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| Journal |
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| Sequence |
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| LinkDB |
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