| Entry |
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| Symbol |
COMT
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| Name |
caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase [EC: 2.1.1.68 2.1.1.4 2.1.1.42]
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| Pathway |
| map00944 | Flavone and flavonol biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00039 | Monolignol biosynthesis, phenylalanine/tyrosine => monolignol |
| M00936 | Melatonin biosynthesis, plants, tryptophan => serotonin => melatonin |
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| Reaction |
| R02379 | S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase |
| R03130 | S-adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase |
| R03366 | S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase |
| R03587 | S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase |
| R06574 | caffeic aldehyde:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase |
| R06575 | S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase |
| R06576 | S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase |
| R06577 | S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00380 Tryptophan metabolism
K13066 COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase
09110 Biosynthesis of other secondary metabolites
00940 Phenylpropanoid biosynthesis
K13066 COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase
00944 Flavone and flavonol biosynthesis
K13066 COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.4 acetylserotonin O-methyltransferase
K13066 COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase
2.1.1.42 flavone 3'-O-methyltransferase
K13066 COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase
2.1.1.68 caffeate O-methyltransferase
K13066 COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase / flavone 3'-O-methyltransferase
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Zubieta C, Kota P, Ferrer JL, Dixon RA, Noel JP |
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| Title |
Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Byeon Y, Lee HY, Lee K, Back K |
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| Title |
Caffeic acid O-methyltransferase is involved in the synthesis of melatonin by methylating N-acetylserotonin in Arabidopsis. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Muzac I, Wang J, Anzellotti D, Zhang H, Ibrahim RK |
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| Title |
Functional expression of an Arabidopsis cDNA clone encoding a flavonol 3'-O-methyltransferase and characterization of the gene product. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Gauthier A, Gulick PJ, Ibrahim RK |
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| Title |
Characterization of two cDNA clones which encode O-methyltransferases for the methylation of both flavonoid and phenylpropanoid compounds. |
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| Journal |
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| Sequence |
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| LinkDB |
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