Entry
Symbol
eryCIII
Name
3-alpha-mycarosylerythronolide B desosaminyl transferase [EC:
2.4.1.278 ]
Pathway
map00522 Biosynthesis of 12-, 14- and 16-membered macrolides
map01110 Biosynthesis of secondary metabolites
Module
M00774 Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B
Reaction
R05531 dTDP-D-desosamine:3-O-mycarosylerythronolide-B 5-O-beta-D-desosaminyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K14368 eryCIII; 3-alpha-mycarosylerythronolide B desosaminyl transferase
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
K14368 eryCIII; 3-alpha-mycarosylerythronolide B desosaminyl transferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K14368 eryCIII; 3-alpha-mycarosylerythronolide B desosaminyl transferase
Enzymes [BR:ko01000 ]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.278 3-alpha-mycarosylerythronolide B desosaminyl transferase
K14368 eryCIII; 3-alpha-mycarosylerythronolide B desosaminyl transferase
Polyketide biosynthesis proteins [BR:ko01008 ]
Polyketide tailoring proteins
Glycosyltransferase
K14368 eryCIII; 3-alpha-mycarosylerythronolide B desosaminyl transferase
BRITE hierarchy
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Genes
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Reference
Authors
Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L.
Title
Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.
Journal
Sequence
Reference
Authors
Salah-Bey K, Doumith M, Michel JM, Haydock S, Cortes J, Leadlay PF, Raynal MC
Title
Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea.
Journal
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