KEGG   ORTHOLOGY: K19443
Entry
K19443                      KO                                     

Symbol
UL54
Name
Simplexvirus mRNA export factor
Pathway
map05168  Herpes simplex virus 1 infection
Network
nt06122  IFN signaling (viruses)
nt06140  Transcription (viruses)
nt06168  Herpes simplex virus 1 (HSV-1)
  Element
N00575  HSV ICP27 to IFN signaling pathway
N00587  HSV ICP27 to Nuclear export of mRNA
N00588  HSV VP16 to Oct-1-mediated transcription
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K19443  UL54; Simplexvirus mRNA export factor
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19443  UL54; Simplexvirus mRNA export factor
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human herpes simplex virus
   K19443  UL54; Simplexvirus mRNA export factor
Genes
VG: 1487343(UL54) 1487450(UL54) 18533947(UL54) 19621701(UL54) 24271474(UL54) 3190364(UL54) 3850206(UL54) 9829303(UL54)
Reference
PMID:9512520
  Authors
Sandri-Goldin RM
  Title
ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif.
  Journal
Genes Dev 12:868-79 (1998)
DOI:10.1101/gad.12.6.868
  Sequence
Reference
  Authors
Tunnicliffe RB, Schacht M, Levy C, Jowitt TA, Sandri-Goldin RM, Golovanov AP
  Title
The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.
  Journal
Sci Rep 5:11234 (2015)
DOI:10.1038/srep11234
  Sequence
LinkDB

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