| Entry |
|
| Name |
HSV ICP27 to IFN signaling pathway
|
| Definition |
ICP27 -| (STAT1+STAT2+IRF9) |
| Expanded |
K19443 -| (6772+6773+10379) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
| hsa05168 | Herpes simplex virus 1 infection |
|
| Disease |
| H00365 | Herpes simplex virus infection |
|
| Gene |
| 6772 | STAT1; signal transducer and activator of transcription 1 |
| 6773 | STAT2; signal transducer and activator of transcription 2 |
| 10379 | IRF9; interferon regulatory factor 9 |
|
| Perturbant |
| K19443 (ICP27) | UL54; Simplexvirus mRNA export factor |
|
| Reference |
|
| Authors |
Melchjorsen J, Matikainen S, Paludan SR |
| Title |
Activation and evasion of innate antiviral immunity by herpes simplex virus. |
| Journal |
|
| Reference |
|
| Authors |
Johnson KE, Song B, Knipe DM |
| Title |
Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. |
| Journal |
|
| Reference |
|
| Authors |
Nan Y, Wu C, Zhang YJ |
| Title |
Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism. |
| Journal |
|
| LinkDB |
|