Entry |
|
Name |
HSV ICP27 to IFN signaling pathway
|
Definition |
ICP27 -| (STAT1+STAT2+IRF9) |
Expanded |
K19443 -| (6772+6773+10379) |
Class |
|
Type |
Pathogen
|
Pathway |
hsa05168 | Herpes simplex virus 1 infection |
|
Disease |
H00365 | Herpes simplex virus infection |
|
Gene |
6772 | STAT1; signal transducer and activator of transcription 1 |
6773 | STAT2; signal transducer and activator of transcription 2 |
10379 | IRF9; interferon regulatory factor 9 |
|
Perturbant |
K19443 (ICP27) | UL54; Simplexvirus mRNA export factor |
|
Reference |
|
Authors |
Melchjorsen J, Matikainen S, Paludan SR |
Title |
Activation and evasion of innate antiviral immunity by herpes simplex virus. |
Journal |
|
Reference |
|
Authors |
Johnson KE, Song B, Knipe DM |
Title |
Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. |
Journal |
|
Reference |
|
Authors |
Nan Y, Wu C, Zhang YJ |
Title |
Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism. |
Journal |
|
LinkDB |
|