 | | ORTHOLOGY: K19643 | |
| Entry |
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| Symbol |
dfrA10, dfr10
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| Name |
dihydrofolate reductase (trimethoprim resistance protein) [EC: 1.5.1.3]
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| Pathway |
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| Reaction |
| R00936 | 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase |
| R00937 | 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase |
| R00939 | 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase |
| R00940 | 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase |
| R02235 | dihydrofolate:NAD+ oxidoreductase |
| R02236 | dihydrofolate:NADP+ oxidoreductase |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
00670 One carbon pool by folate
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
Enzymes [BR:ko01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance genes [BR:ko01504]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance: KEGG signatures [br01600.html]
Signature KOs for antimicrobial resistance
K19643
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| Other DBs |
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| Genes |
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| Reference |
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| Authors |
Parsons Y, Hall RM, Stokes HW |
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| Title |
A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Partridge SR, Hall RM |
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| Title |
In34, a complex In5 family class 1 integron containing orf513 and dfrA10. |
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| Journal |
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| LinkDB |
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