REACTION: R02235
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Entry
R02235 Reaction
Name
dihydrofolate:NAD+ oxidoreductase
Definition
Dihydrofolate + NAD+ <=> Folate + NADH + H+
Equation
C00415
+
C00003
<=>
C00504
+
C00004
+
C00080
Reaction class
RC00001
C00003_C00004
RC00158
C00415_C00504
Enzyme
1.5.1.3
Pathway
rn00670
One carbon pool by folate
rn00790
Folate biosynthesis
rn01100
Metabolic pathways
rn01240
Biosynthesis of cofactors
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3
R02235 Dihydrofolate + NAD+ <=> Folate + NADH + H+
BRITE hierarchy
Orthology
K00287
dihydrofolate reductase [EC:
1.5.1.3
]
K13998
dihydrofolate reductase / thymidylate synthase [EC:
1.5.1.3
2.1.1.45
]
K18589
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
K18590
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
K18591
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
K19643
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
K19644
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
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