KEGG ORTHOLOGY: K20917

ORTHOLOGY: K20917

Entry

K20917                      KO

Symbol

GSDMD

Name

gasdermin-D

Pathway

map04613

Neutrophil extracellular trap formation

map04621

NOD-like receptor signaling pathway

map04623

Cytosolic DNA-sensing pathway

map05132

Salmonella infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K20917  GSDMD; gasdermin-D
   04621 NOD-like receptor signaling pathway
    K20917  GSDMD; gasdermin-D
   04623 Cytosolic DNA-sensing pathway
    K20917  GSDMD; gasdermin-D
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K20917  GSDMD; gasdermin-D
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K20917  GSDMD; gasdermin-D
Transporters [BR:ko02000]
Other transporters
  Pores ion channels
   K20917  GSDMD; gasdermin-D

Other DBs

TC:	1.C.123.1.1

Genes

HSA:	79792(GSDMD)

PTR:	739712(GSDMD)

PPS:	100975449(GSDMD)

GGO:	129524082(GSDMD)

PON:	100439852(GSDMD)

PPYG:

129042381(GSDMD)

HMH:	116813661(GSDMD)

SSYN:

129486896(GSDMD)

MCC:	697137(GSDMD)

MCF:	102119296(GSDMD)

MTHB:

126961019

MNI:	105488447(GSDMD)

CSAB:

103237567(GSDMD)

CATY:

105581203(GSDMD)

PANU:

101011806(GSDMD)

TGE:	112630439(GSDMD)

MLEU:

105536297(GSDMD)

RRO:	104679790(GSDMD)

RBB:	108536565(GSDMD)

TFN:	117078831(GSDMD)

PTEH:

111553334(GSDMD)

CANG:

105509116(GSDMD)

CJC:	100412430(GSDMD)

SBQ:	101047124(GSDMD)

CIMI:

108291281(GSDMD)

ANAN:

105723293(GSDMD)

CSYR:

103259057(GSDMD)

MMUR:

105864786(GSDMD)

LCAT:

123644911(GSDMD)

ERUF:

138381581(GSDMD)

PCOQ:

105813295(GSDMD)

OGA:	100966643(GSDMD)

MMU:	69146(Gsdmd)

MCAL:

110310447(Gsdmd)

MPAH:

110335163(Gsdmd)

RNO:	315084(Gsdmd)

MCOC:

116074193(Gsdmd)

ANU:	117718475 117718638 117719262 117719265 117719373

ASYL:

127667919(Gsdmd)

MUN:	110563085(Gsdmd)

CGE:	100756673(Gsdmd)

MAUA:

101834419(Gsdmd)

PROB:

127225661(Gsdmd)

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103735290(Gsdmd)

HGL:	101723292(Gsdmd)

CPOC:

100729702(Gsdmd)

CCAN:

109690826(Gsdmd)

DORD:

105999020(Gsdmd)

DSP:	122098921(Gsdmd)

DMER:

138829590

PLOP:

125360906(Gsdmd)

NCAR:

124990483

MMMA:

107142984(Gsdmd)

ITI:	101964895(Gsdmd)

OCU:

100338635

OPI:	101520159(GSDMD)

OCZ:	121163923(GSDMD)

TUP:	102498766(GSDMD)

GVR:	103599002(GSDMD)

CFA:	609395(GSDMD)

CLUD:

112662264(GSDMD)

VVP:	112911134(GSDMD)

VLG:	121499132(GSDMD)

NPO:	129502660(GSDMD)

AML:	100484366(GSDMD)

UMR:	103656671(GSDMD)

UAH:	113247658(GSDMD)

UAR:	123779295(GSDMD)

ELK:

111146616

LLV:

125097200

MPUF:

101672437(GSDMD)

MNP:	132014358(GSDMD)

MLK:	131827766(GSDMD)

NVS:	122905489 122905491 122905493

ORO:	101375370(GSDMD)

EJU:	114201056(GSDMD)

ZCA:	113932682(GSDMD)

MLX:	118015271(GSDMD)

MANO:

123858664(GSDMD)

NSU:	110579193(GSDMD)

LWW:	102742746(GSDMD)

FCA:	101089493(GSDMD)

PYU:	121043101(GSDMD)

PBG:	122495895(GSDMD)

PVIV:

125156158(GSDMD)

LRUF:

124507856

LGF:	123585356(GSDMD)

AJU:

106981485

PTG:	102959421(GSDMD)

PPAD:

109258300(GSDMD)

PUC:

125924339

PLEZ:

122210907(GSDMD)

HHV:	120246573(GSDMD)

CCRU:

144226725(GSDMD)

BTA:	513939(GSDMD)

BOM:	102286911(GSDMD)

BIU:	109568375(GSDMD)

BJV:	133260112(GSDMD)

BBUB:

102393748(GSDMD)

BKE:	129626510(GSDMD)

BBIS:

104999074(GSDMD)

CHX:	102185480(GSDMD)

OAS:	101117254(GSDMD)

OCAN:

138445632(GSDMD)

BTAX:

128059451(GSDMD)

CSUM:

138088472(GSDMD)

ODA:	120878762(GSDMD)

CCAD:

122451442(GSDMD)

MREE:

136145251(GSDMD)

OVR:	110129591(GSDMD)

MBEZ:

129560224(GSDMD)

SSC:	100515607(GSDMD)

CFR:	102511831(GSDMD)

CBAI:

105073791(GSDMD)

CDK:	105105691(GSDMD)

VPC:	102525637(GSDMD)

BACU:

103007502(GSDMD)

BMUS:

118883418(GSDMD)

LVE:	103078871(GSDMD)

OOR:	101272236(GSDMD)

LALB:

132508099(GSDMD)

GMF:	115863332(GSDMD)

DDP:	132440417(GSDMD)

DLE:	111165112(GSDMD)

PCAD:

102995659(GSDMD)

PSIU:

116742432(GSDMD)

PPHC:

136137324(GSDMD)

NASI:

112397061(GSDMD)

ECB:	100063519(GSDMD)

EPZ:	103561591(GSDMD)

EAI:	106841898(GSDMD)

MYB:	102257293(GSDMD)

MYD:	102764031(GSDMD)

MMYO:

118653172(GSDMD)

MDT:	132219809(GSDMD)

MYUM:

138993304(GSDMD)

PKL:	118718628(GSDMD)

EFUS:

103302716(GSDMD)

MNA:	107542742(GSDMD)

DRO:	112315694(GSDMD)

SHON:

118988843(GSDMD)

AJM:	119064645(GSDMD)

PDIC:

114514452(GSDMD)

PHAS:

123832964(GSDMD)

MMF:	118643351(GSDMD)

PPAM:

129084361(GSDMD)

HAI:	109390835(GSDMD)

RFQ:	117033565(GSDMD)

PALE:

102882398(GSDMD)

PGIG:

120588784(GSDMD)

PVP:	105301988(GSDMD)

RAY:	107507897(GSDMD)

MJV:	108402832(GSDMD)

TOD:	119231897(GSDMD)

SARA:

101546147(GSDMD)

SFUM:

130033367(GSDMD)

SETR:

125997201(GSDMD)

LAV:	100676190(GSDMD)

TMU:

101346782

ETF:	101661042(GSDMD)

DNM:	101414994(GSDMD)

MDO:	103101815(GSDMD)

GAS:	123255871(GSDMD)

SHR:

100934670

AFZ:

127544537

PCW:	110214179(GSDMD)

TVP:	118829529 118833794 118834680 118857848

PBRV:

138167949 138167950 138167953

APRI:

131197125(GSDMD)

VKO:

123031791

» show all

Reference

PMID:26375003

Authors

Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F, Shao F

Title

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Journal

Nature 526:660-5 (2015)
DOI:10.1038/nature15514

Sequence

[hsa:79792]

LinkDB

DBGET integrated database retrieval system