KEGG ORTHOLOGY: K23404

ORTHOLOGY: K23404

Entry

K23404                      KO

Symbol

TAPT1

Name

transmembrane anterior posterior transformation protein 1

Disease

H02280

Complex lethal osteochondrodysplasia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K23404  TAPT1; transmembrane anterior posterior transformation protein 1
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  Other primary cilia associated proteins
   K23404  TAPT1; transmembrane anterior posterior transformation protein 1

Genes

HSA:	202018(TAPT1)

PTR:	461128(TAPT1)

PPS:	100977078(TAPT1)

GGO:	101150188(TAPT1)

PON:	100459364(TAPT1)

NLE:	100579674(TAPT1)

HMH:	116456786(TAPT1)

MCC:	714712(TAPT1)

MCF:	102131000(TAPT1)

MTHB:

126955679

MNI:	105487900(TAPT1)

CSAB:

103246320(TAPT1)

CATY:

105579030(TAPT1)

PANU:

101020429(TAPT1)

TGE:	112625163(TAPT1)

MLEU:

105542548(TAPT1)

RRO:	104658175(TAPT1)

RBB:	108531736(TAPT1)

TFN:	117085181(TAPT1)

PTEH:

111539173(TAPT1)

CANG:

105516569(TAPT1)

CJC:	100386267(TAPT1)

SBQ:	101037706(TAPT1)

CIMI:

108282744(TAPT1)

CSYR:

103270909(TAPT1)

MMUR:

105856075(TAPT1)

LCAT:

123637318(TAPT1)

PCOQ:

105805577(TAPT1)

OGA:	100961750(TAPT1)

MMU:	231225(Tapt1)

MCAL:

110294814(Tapt1)

MPAH:

110330498(Tapt1)

RNO:	305386(Tapt1)

MCOC:

116070694(Tapt1)

ANU:	117712663(Tapt1)

MUN:	110559151(Tapt1)

CGE:	100761495(Tapt1)

MAUA:

101827745(Tapt1)

PROB:

127213592(Tapt1)

PLEU:

114690874(Tapt1)

MORG:

121436455(Tapt1)

MFOT:

126506470

AAMP:

119801510(Tapt1)

NGI:	103728879(Tapt1)

HGL:	101717174(Tapt1)

CPOC:

100727093(Tapt1)

CCAN:

109691562(Tapt1)

DORD:

105980327(Tapt1)

DSP:	122104086(Tapt1)

PLOP:

125364409(Tapt1)

NCAR:

124994433

MMMA:

107139143(Tapt1)

OCU:

100354591

OPI:	101532023(TAPT1)

TUP:	102499273(TAPT1)

GVR:	103591707(TAPT1)

CFA:	488815(TAPT1)

CLUD:

112653225(TAPT1)

VVP:	112922599(TAPT1)

VLG:	121489333(TAPT1)

NPO:	129510370(TAPT1)

AML:	100464727(TAPT1)

UMR:	103658363(TAPT1)

UAH:	113266712(TAPT1)

UAR:	123775792(TAPT1)

ELK:

111149202

LLV:

125093564

MPUF:

101685965(TAPT1)

MNP:	132004804(TAPT1)

MLK:	131825618(TAPT1)

NVS:	122890456(TAPT1)

ORO:	101364039(TAPT1)

EJU:	114196500(TAPT1)

ZCA:	113924401(TAPT1)

MLX:	118010679(TAPT1)

NSU:	110571342(TAPT1)

LWW:	102747099(TAPT1)

FCA:	101081135(TAPT1)

PYU:	121042692(TAPT1)

PCOO:

112858653(TAPT1)

PBG:	122479015(TAPT1)

PVIV:

125163945(TAPT1)

LRUF:

124519999

PTG:	102954042(TAPT1)

PPAD:

109269553(TAPT1)

PUC:

125922655

AJU:

106975629

HHV:	120237988(TAPT1)

BTA:	615598(TAPT1)

BOM:	102284192(TAPT1)

BIU:	109560689(TAPT1)

BBUB:

102406459(TAPT1)

BBIS:

105001135(TAPT1)

CHX:	102174008(TAPT1)

OAS:	101107445(TAPT1)

BTAX:

128049473(TAPT1)

ODA:	120861773(TAPT1)

CCAD:

122428079(TAPT1)

SSC:	100626638(TAPT1)

CFR:	102506439(TAPT1)

CBAI:

105083242(TAPT1)

CDK:	105098343(TAPT1)

VPC:	102532032(TAPT1)

BACU:

102998838(TAPT1)

BMUS:

118895475(TAPT1)

LVE:	103081283(TAPT1)

OOR:	101280444(TAPT1)

DLE:	111171373(TAPT1)

PCAD:

102980487(TAPT1)

PSIU:

116754303(TAPT1)

NASI:

112397544(TAPT1)

ECB:	100068801(TAPT1)

EPZ:	103548354(TAPT1)

EAI:	106829604(TAPT1)

MYB:	102250772(TAPT1)

MYD:	102760989(TAPT1)

MMYO:

118666965(TAPT1)

MLF:	102438151(TAPT1)

PKL:	118708705(TAPT1)

EFUS:

103294477(TAPT1)

MNA:	107527120(TAPT1)

DRO:	112316739(TAPT1)

SHON:

118986528(TAPT1)

AJM:	119035470(TAPT1)

PDIC:

114492442(TAPT1)

PHAS:

123815743(TAPT1)

MMF:	118620443(TAPT1)

PPAM:

129077538(TAPT1)

HAI:	109372162(TAPT1) 109389293

RFQ:	117022252(TAPT1)

PALE:

102889508(TAPT1)

PGIG:

120582810(TAPT1)

PVP:	105295300(TAPT1)

RAY:	107507358(TAPT1)

MJV:	108392613(TAPT1)

TOD:	119260166(TAPT1)

SARA:

101553631(TAPT1)

SETR:

126032570(TAPT1)

LAV:	100661434(TAPT1)

TMU:

101347415

ETF:	101649615(TAPT1)

DNM:	101434121(TAPT1)

MDO:	100015300(TAPT1)

GAS:	123252969(TAPT1)

SHR:	100914592(TAPT1)

AFZ:

127541813

PCW:	110212797(TAPT1)

OAA:	100074400(TAPT1)

GGA:	422824(TAPT1)

PCOC:

116225815(TAPT1)

MGP:	100547983(TAPT1)

CJO:	107313984(TAPT1)

TPAI:

128080101(TAPT1)

LMUT:

125692537(TAPT1)

NMEL:

110397868(TAPT1)

APLA:

101800365(TAPT1)

ACYG:

106035448(TAPT1)

CATA:

118259457(TAPT1)

AFUL:

116488822(TAPT1)

TGU:	100229503(TAPT1)

LSR:	110484065(TAPT1)

SCAN:

103824381(TAPT1)

PMOA:

120497391(TAPT1)

OTC:	121335002(TAPT1)

PRUF:

121356314(TAPT1)

GFR:	102033411(TAPT1)

FAB:	101812297(TAPT1)

OMA:	130252310(TAPT1)

PHI:	102099983(TAPT1)

PMAJ:

107203178(TAPT1)

CCAE:

111928164(TAPT1)

CCW:	104690717(TAPT1)

CBRC:

103625587(TAPT1)

ETL:	114061122(TAPT1)

ZAB:	102060557(TAPT1)

ACHL:

103799405(TAPT1)

SVG:	106864084(TAPT1)

MMEA:

130578385(TAPT1)

HRT:	120753161(TAPT1)

FPG:	101911453(TAPT1)

FCH:	102047583(TAPT1)

CLV:	102088679(TAPT1)

EGZ:	104134482(TAPT1)

NNI:	104010758(TAPT1)

PCRI:

104028564(TAPT1)

PLET:

104621469(TAPT1)

EHS:	104510736(TAPT1)

ACUN:

113479189(TAPT1)

TALA:

104357542(TAPT1)

PADL:

103916991(TAPT1)

AFOR:

103898766(TAPT1)

ACHC:

115339106(TAPT1)

HALD:

104318114(TAPT1)

HLE:	104837603(TAPT1)

AGEN:

126034324

GCL:

127015463

CCRI:

104169379(TAPT1)

CSTI:

104564061(TAPT1)

BREG:

104633085(TAPT1)

FGA:	104078916(TAPT1)

LDI:	104343987(TAPT1)

OHA:	104329228(TAPT1)

NNT:	104402452(TAPT1) 104413370

SHAB:

115610895(TAPT1)

DPUB:

104309164(TAPT1)

PGUU:

104471741(TAPT1)

ACAR:

104522934(TAPT1)

CPEA:

104393582(TAPT1)

AVIT:

104268784(TAPT1)

CVF:	104288770(TAPT1)

RTD:	128910668(TAPT1)

CUCA:

104067458(TAPT1)

TEO:	104383504(TAPT1)

BRHI:

104490092(TAPT1)

AAM:	106498735(TAPT1)

AROW:

112970828(TAPT1)

NPD:	112958526(TAPT1)

TGT:	104580409(TAPT1)

DNE:	112996486(TAPT1)

SCAM:

104143035(TAPT1)

ASN:	102379783(TAPT1)

AMJ:	102567045(TAPT1)

CPOO:

109322195(TAPT1)

GGN:	109303926(TAPT1)

PSS:	102447552(TAPT1)

CMY:	102934540(TAPT1)

CCAY:

125636142(TAPT1)

DCC:	119854377(TAPT1)

CPIC:

101937744(TAPT1)

TST:	117877691(TAPT1)

CABI:

116821054(TAPT1)

MRV:	120406177(TAPT1)

ACS:	100555099(tapt1)

ASAO:

132776362(TAPT1)

PVT:	110085955(TAPT1)

SUND:

121932148(TAPT1)

PBI:	103058286(TAPT1)

PMUR:

107289982(TAPT1)

CTIG:

120300467(TAPT1)

TSR:	106549885(TAPT1)

PGUT:

117680195(TAPT1)

APRI:

131202849(TAPT1)

PTEX:

113435738(TAPT1)

NSS:	113419460(TAPT1)

VKO:	123016928(TAPT1)

PMUA:

114603871(TAPT1)

PRAF:

128420804(TAPT1)

ZVI:	118083672(TAPT1)

HCG:	128326983(TAPT1)

GJA:	107108465 107123883

STOW:

125439962(TAPT1)

EMC:	129343424(TAPT1)

XLA:	108698043(tapt1.L) 734322(tapt1.S)

XTR:	100491675(tapt1)

NPR:	108793579(TAPT1)

RTEM:

120924328(TAPT1)

BBUF:

120990326(TAPT1)

BGAR:

122940293(TAPT1)

MUO:	115461424(TAPT1)

GSH:	117362444(TAPT1)

DRE:	558330(tapt1a) 559710(tapt1b)

SRX:	107741129 107750443 107756466

SANH:

107671913 107680612 107694978 107702406

SGH:	107548305 107550875(tapt1) 107562598 107601446

CCAR:

109047983 109101152 109102483

CAUA:

113044258 113070650 113091099 113107553 113108285 113114046

CGIB:

127949261 127957560 127971153 128027557

PTET:

122348333(tapt1b) 122357904(tapt1a) 122357943

LROH:

127167878(tapt1b) 127176534(tapt1a)

OMC:	131546501(tapt1b) 131553851(tapt1a)

PPRM:

120460986 120494191(tapt1b)

RKG:	130089559(tapt1b) 130089740(tapt1a)

MAMB:

125259065(tapt1a) 125272650(tapt1b)

CIDE:

127494382 127495724

MASI:

127413039 127418328 127443635 127444545

TROS:

130553532(tapt1b) 130563895(tapt1a)

TDW:	130413456(tapt1b) 130438369(tapt1a)

MANU:

129421947(tapt1a) 129444627(tapt1b)

IPU:	108260958(tapt1b) 108269149(tapt1a)

IFU:	128604298(tapt1b) 128611909(tapt1a)

PHYP:

113542832 113544212

SMEO:

124381316(tapt1b) 124385856(tapt1a)

TFD:	113647757(tapt1a) 113660707(tapt1b)

TVC:	132841880(tapt1b) 132855890(tapt1a)

AMEX:

103038627 103043525

CMAO:

118807020(tapt1a) 118816575(tapt1b)

EEE:	113570774 113587696(tapt1)

CHAR:

105904414(tapt1a) 105908524(tapt1b)

TRU:	101064041(tapt1) 101069303

TFS:	130526698(tapt1b) 130530967(tapt1a)

TNG:	GSTEN00007224G001 GSTEN00024443G001

LCO:	104919402 104934196(tapt1)

NCC:	104943413 104946457 104962902(tapt1)

TBEN:

117482302(tapt1b) 117485251(tapt1a)

CGOB:

115012957 115014591

PGEO:

117448447(tapt1b) 117454009(tapt1a)

GACU:

117551620 117556228(tapt1b)

EMAC:

134860196(tapt1a) 134865046(tapt1b)

ELY:	117255781(tapt1b) 117261028(tapt1a)

EFO:	125886099(tapt1b) 125894029(tapt1a)

PLEP:

121942535(tapt1b) 121947785(tapt1a)

SLUC:

116034345(tapt1b) 116062432(tapt1a)

ECRA:

117952304(tapt1a) 117960835(tapt1b)

ESP:	116696392(tapt1) 116698821

PFLV:

114545569 114563280(tapt1)

GAT:	120817023(tapt1a) 120825526(tapt1b)

PPUG:

119210933(tapt1a) 119218416(tapt1b)

AFB:	129089882(tapt1a) 129095984(tapt1b)

CLUM:

117734793(tapt1b) 117737675(tapt1a)

PSWI:

130190539(tapt1b) 130209869(tapt1a)

MSAM:

119888737(tapt1a) 119898816(tapt1b)

SCHU:

122873267(tapt1b) 122880694(tapt1a)

CUD:	121508498(tapt1b) 121515943(tapt1a)

ALAT:

119007019(tapt1a) 119020737(tapt1b)

MZE:	101472940 101481533(tapt1)

ONL:	100692183(tapt1) 100710485

OAU:	116334004(tapt1b) 116334521(tapt1a)

OLA:	101156305 101156556

OML:	112137507(tapt1b) 112145001(tapt1a)

CSAI:

133441423(tapt1b) 133447457(tapt1a)

XMA:	102233431(tapt1) 102238385

XCO:	114138763 114143974

XHE:	116715043 116720329

PRET:

103460108(tapt1) 103471856

PFOR:

103136394 103136470 103136471 103137318 103137319

PLAI:

106939962 106947874 106964579(tapt1)

PMEI:

106904348 106908329(tapt1) 106932374 106933729

GAF:	122830411(tapt1b) 122836724(tapt1a)

PPRL:

129360291 129360297 129376912(tapt1b)

CVG:	107089187 107090486(tapt1)

CTUL:

119774327(tapt1b)

GMU:	124860382(tapt1a) 124868444(tapt1b)

NFU:	107380101(tapt1) 107380809

KMR:	108230729(tapt1b) 108236612(tapt1a)

ALIM:

106525852(tapt1) 106532668

NWH:	119408754(tapt1a) 119422567(tapt1b)

AOCE:

111567649 111586727 111586799

MCEP:

125003962(tapt1b) 125008334(tapt1a)

CSEM:

103383645(tapt1) 103390687

POV:	109638380(tapt1) 109640022

SSEN:

122771452(tapt1b) 122778883(tapt1a)

HHIP:

117765857(tapt1b) 117769449(tapt1a)

HSP:	118112271(tapt1a) 118122278(tapt1b)

SMAU:

118312877(tapt1b) 118319714(tapt1a)

LCF:	108890670(tapt1a) 108893112(tapt1b)

SDU:	111216735(tapt1) 111232600

SLAL:

111656730 111657370(tapt1)

XGL:	120785239(tapt1a) 120800590(tapt1b)

HCQ:	109511470(tapt1) 109526266

SSCV:

125968381 125983027

SBIA:

133506481(tapt1b) 133508913(tapt1a)

PEE:	133404409(tapt1b) 133407686(tapt1a)

PTAO:

133476714(tapt1b) 133484737(tapt1a)

BPEC:

110153733 110167553(tapt1)

MALB:

109953769 109956310(tapt1) 109972110

BSPL:

114853875(tapt1b) 114863970(tapt1a)

SJO:	128362653(tapt1a) 128375975(tapt1b)

SASA:

106594021 106604538 106611550

STRU:

115170500 115183507 115183508 115185831 115205096

OTW:	112221062(tapt1a) 112256349

OMY:	110488944 110505143 110519477 118947002

OGO:	123993526 124011239 124020869 124021429 124028280

ONE:	115129562 115130827

OKI:	109905291 109910170 116361505 116370013

OKE:	118363602 118379759 127925714(tapt1b)

SALP:

111965844 111967591

SNH:	120048022 120062239

CCLU:

121535448 121540604 121562768

ELS:	105007586(tapt1) 105026035

SFM:	108924557(tapt1) 108930851

PKI:	111833719 111837337(tapt1)

AANG:

118228133(tapt1b) 118231982(tapt1a)

LOC:	102693140(tapt1)

PSPA:

121324471 121329872

ARUT:

117409494 117421340

PSEX:

120527751(tapt1b)

LCM:	102367464(TAPT1)

CMK:	103175883(tapt1b)

RTP:

CPLA:

HOC:

LERI:

PMRN:

116944699(TAPT1)

LRJ:	133340088(TAPT1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:	117102248 117102263

SKO:

100371362

DME:	Dmel_CG7218(CG7218)

DER:

26526744

DSE:

116801548

DSI:	Dsimw501_GD27994(Dsim_GD27994)

DYA:	Dyak_GE28247

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI26049

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119683081 119690033

MDE:	101888792 131802707 131802709

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CPII:

CNS:

BCOO:

AME:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_203222

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:	100164137 100168246

DNX:	107164988 107169613

AGS:

114129867

RMD:	113555152 113559689

ACOO:

126833598

DVT:

126906787

BTAB:

109037098

DCI:	103517670 103521793

CLEC:

HHAL:

NLU:

HVI:

PHU:	Phum_PHUM239120

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_311679

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:	119434467 119434647 119456068

RSAN:

RMP:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F26F2.7(F26F2.7)

CBR:

CBG_05609

CRQ:	GCK72_021888

NAI:	NECAME_05892

BMY:	BM_BM3623(Bm3623)

LOA:	LOAG_01351

TSP:

Tsp_04290

HRO:	HELRODRAFT_186784

LGI:	LOTGIDRAFT_82778

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_175200

OVI:	T265_14118

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130645692 130645851

TAD:	TRIADDRAFT_28365

AQU:

100634344

DPP:	DICPUDRAFT_99083

ACAN:

ACA1_048140 ACA1_112930 ACA1_112940

» show all

Reference

PMID:26365339

Authors

Symoens S, Barnes AM, Gistelinck C, Malfait F, Guillemyn B, Steyaert W, Syx D, D'hondt S, Biervliet M, De Backer J, Witten EP, Leikin S, Makareeva E, Gillessen-Kaesbach G, Huysseune A, Vleminckx K, Willaert A, De Paepe A, Marini JC, Coucke PJ

Title

Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia.

Journal

Am J Hum Genet 97:521-34 (2015)
DOI:10.1016/j.ajhg.2015.08.009

Sequence

[hsa:202018]

LinkDB

DBGET integrated database retrieval system