KEGG   ORTHOLOGY: K23655
Entry
K23655                      KO                                     
Symbol
nleC
Name
T3SS secreted effector NleC
Pathway
map05130  Pathogenic Escherichia coli infection
Network
nt06180  Pathogenic Escherichia coli
nt06516  TNF signaling
  Element
N00929  Escherichia NleC to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K23655  nleC; T3SS secreted effector NleC
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K23655  nleC; T3SS secreted effector NleC
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M85
   K23655  nleC; T3SS secreted effector NleC
Genes
ECE: Z0986
ECS: ECs_0847(nleC)
ECF: ECH74115_0918
ETW: ECSP_0866(nleC)
ELX: CDCO157_0825
EOI: ECO111_2392 ECO111_2554
EOJ: ECO26_2220
ECOO: ECRM13514_2013(nleC)
ECOH: ECRM13516_1911(nleC) ECRM13516_2281(nleC_2)
ECG: E2348C_1042
EOK: G2583_0996(nleC)
ELR: ECO55CA74_04835
SEJ: STMUK_2657
SEEN: SE451236_19355
SENJ: CFSAN001992_20550
CRO: ROD_16491(nleC)
YAL: AT01_367
YAS: N0H69_14210
PEW: KZJ38_32490
 » show all
Reference
PMID:21187904
  Authors
Yen H, Ooka T, Iguchi A, Hayashi T, Sugimoto N, Tobe T
  Title
NleC, a type III secretion protease, compromises NF-kappaB activation by targeting p65/RelA.
  Journal
PLoS Pathog 6:e1001231 (2010)
DOI:10.1371/journal.ppat.1001231
  Sequence
[ecs:ECs_0847]
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