KEGG   ORTHOLOGY: K23655
Entry
K23655                      KO                                     
Symbol
nleC
Name
T3SS secreted effector NleC
Pathway
map05130  Pathogenic Escherichia coli infection
Network
nt06123  TNF signaling (viruses and bacteria)
  Element
N00929  Escherichia NleC to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K23655  nleC; T3SS secreted effector NleC
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K23655  nleC; T3SS secreted effector NleC
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M85
   K23655  nleC; T3SS secreted effector NleC
Genes
ECE: Z0986
ECS: ECs_0847(nleC)
ECF: ECH74115_0918
ETW: ECSP_0866(nleC)
ELX: CDCO157_0825
EOI: ECO111_2392 ECO111_2554
EOJ: ECO26_2220
ECOO: ECRM13514_2013(nleC)
ECOH: ECRM13516_1911(nleC) ECRM13516_2281(nleC_2)
ECG: E2348C_1042
EOK: G2583_0996(nleC)
ELR: ECO55CA74_04835
SEJ: STMUK_2657
SEEN: SE451236_19355
SENJ: CFSAN001992_20550
CRO: ROD_16491(nleC)
YAL: AT01_367
PEW: KZJ38_32490
 » show all
Reference
PMID:21187904
  Authors
Yen H, Ooka T, Iguchi A, Hayashi T, Sugimoto N, Tobe T
  Title
NleC, a type III secretion protease, compromises NF-kappaB activation by targeting p65/RelA.
  Journal
PLoS Pathog 6:e1001231 (2010)
DOI:10.1371/journal.ppat.1001231
  Sequence
[ecs:ECs_0847]
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