KEGG   MODULE: M00173
Entry
M00173            Pathway   Module                                 
Name
Reductive citrate cycle (Arnon-Buchanan cycle)
Definition
(K00169+K00170+K00171+K00172,K03737) ((K01007,K01006) K01595,K01959+K01960,K01958) K00024 (K01676,K01679,K01677+K01678) (K00239+K00240-K00241-K00242,K18556+K18557+K18558+K18559+K18560) (K01902+K01903) (K00174+K00175-K00177-K00176) K00031 (K01681,K27802,K01682) (K15230+K15231,K15232+K15233 K15234)
Diagram
M00173

Orthology
K00169,K00170,K00171,K00172  
pyruvate:ferredoxin oxidoreductase [EC:1.2.7.1] [RN:R01196]
K03737  
pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] [RN:R01196 R10866]
K01007  
pyruvate,water dikinase [EC:2.7.9.2] [RN:R00199]
K01006  
pyruvate,orthophosphate dikinase [EC:2.7.9.1] [RN:R00206]
K01595  
phosphoenolpyruvate carboxylase [EC:4.1.1.31] [RN:R00345]
K01959,K01960,K01958  
pyruvate carboxylase subunit A [EC:6.4.1.1] [RN:R00344]
K00024  
malate dehydrogenase [EC:1.1.1.37] [RN:R00342]
K01676,K01679,K01677,K01678  
fumarate hydratase [EC:4.2.1.2] [RN:R01082]
K00239,K00240,K00241,K00242  
succinate dehydrogenase / fumarate reductase [EC:1.3.5.1 1.3.5.4] [RN:R02164]
K18556,K18557,K18558,K18559,K18560  
NADH-dependent fumarate reductase [EC:1.3.1.6] [RN:R00402]
K01902,K01903  
succinyl-CoA synthetase [EC:6.2.1.5] [RN:R00405]
K00174,K00175,K00177,K00176  
2-oxoglutarate:ferredoxin oxidoreductase [EC:1.2.7.3] [RN:R01197]
K00031  
isocitrate dehydrogenase [EC:1.1.1.42] [RN:R00267]
K01681,K27802,K01682  
aconitate hydratase [EC:4.2.1.3] [RN:R01900 R01325]
K15230,K15231  
ATP-citrate lyase [EC:2.3.3.8] [RN:R00352]
K15232,K15233  
citryl-CoA synthetase [EC:6.2.1.18] [RN:R01322]
K15234  
citryl-CoA lyase [EC:4.1.3.34] [RN:R00354]
Class
Pathway modules; Energy metabolism; Carbon fixation
Pathway
map00720  Other carbon fixation pathways
map01200  Carbon metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R01196,R10866  
R00199,R00206  
R00345  
R00344  
R00342  
R01082  
R02164,R00402  
R00405  
R01197  
R00267  
R01900  
R01325  
R00352  
R01322  
R00354  
Compound
C00024  Acetyl-CoA
C00022  Pyruvate
C00074  Phosphoenolpyruvate
C00036  Oxaloacetate
C00149  (S)-Malate
C00122  Fumarate
C00042  Succinate
C00091  Succinyl-CoA
C00026  2-Oxoglutarate
C00311  Isocitrate
C00417  cis-Aconitate
C00158  Citrate
C00566  (3S)-Citryl-CoA
Reference
PMID:15101982
  Authors
Aoshima M, Ishii M, Igarashi Y
  Title
A novel enzyme, citryl-CoA lyase, catalysing the second step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6.
  Journal
Mol Microbiol 52:763-70 (2004)
DOI:10.1111/j.1365-2958.2004.04010.x
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