KEGG   MODULE: M00173
Entry
M00173            Pathway   Module                                 
Name
Reductive citrate cycle (Arnon-Buchanan cycle)
Definition
(K00169+K00170+K00171+K00172,K03737) ((K01007,K01006) K01595,K01959+K01960,K01958) K00024 (K01676,K01679,K01677+K01678) (K00239+K00240-K00241-K00242,K00244+K00245-K00246-K00247,K18556+K18557+K18558+K18559+K18560) (K01902+K01903) (K00174+K00175-K00177-K00176) K00031 (K01681,K01682) (K15230+K15231,K15232+K15233 K15234)
Diagram
M00173

Orthology
pyruvate:ferredoxin oxidoreductase [EC:1.2.7.1] [RN:R01196]
K03737  
pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] [RN:R01196 R10866]
K01007  
pyruvate,water dikinase [EC:2.7.9.2] [RN:R00199]
K01006  
pyruvate,orthophosphate dikinase [EC:2.7.9.1] [RN:R00206]
K01595  
phosphoenolpyruvate carboxylase [EC:4.1.1.31] [RN:R00345]
pyruvate carboxylase subunit A [EC:6.4.1.1] [RN:R00344]
K00024  
malate dehydrogenase [EC:1.1.1.37] [RN:R00342]
fumarate hydratase [EC:4.2.1.2] [RN:R01082]
succinate dehydrogenase / fumarate reductase [EC:1.3.5.1 1.3.5.4] [RN:R02164]
NADH-dependent fumarate reductase [EC:1.3.1.6] [RN:R00402]
succinyl-CoA synthetase [EC:6.2.1.5] [RN:R00405]
2-oxoglutarate:ferredoxin oxidoreductase [EC:1.2.7.3] [RN:R01197]
K00031  
isocitrate dehydrogenase [EC:1.1.1.42] [RN:R00267]
aconitate hydratase [EC:4.2.1.3] [RN:R01900 R01325]
ATP-citrate lyase [EC:2.3.3.8] [RN:R00352]
citryl-CoA synthetase [EC:6.2.1.18] [RN:R01322]
K15234  
citryl-CoA lyase [EC:4.1.3.34] [RN:R00354]
Class
Pathway modules; Energy metabolism; Carbon fixation
Pathway
map00720  Carbon fixation pathways in prokaryotes
map01200  Carbon metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
Compound
C00024  Acetyl-CoA
C00022  Pyruvate
C00074  Phosphoenolpyruvate
C00036  Oxaloacetate
C00149  (S)-Malate
C00122  Fumarate
C00042  Succinate
C00091  Succinyl-CoA
C00026  2-Oxoglutarate
C00311  Isocitrate
C00417  cis-Aconitate
C00158  Citrate
C00566  (3S)-Citryl-CoA
Reference
  Authors
Aoshima M, Ishii M, Igarashi Y
  Title
A novel enzyme, citryl-CoA lyase, catalysing the second step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6.
  Journal
Mol Microbiol 52:763-70 (2004)
DOI:10.1111/j.1365-2958.2004.04010.x
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