Entry
Symbol
mdh
Name
Pathway
map00270 Cysteine and methionine metabolism
map00630 Glyoxylate and dicarboxylate metabolism
map00710 Carbon fixation in photosynthetic organisms
map00720 Carbon fixation pathways in prokaryotes
map01110 Biosynthesis of secondary metabolites
map01120 Microbial metabolism in diverse environments
Module
M00009 Citrate cycle (TCA cycle, Krebs cycle)
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00168 CAM (Crassulacean acid metabolism), dark
M00173 Reductive citrate cycle (Arnon-Buchanan cycle)
M00346 Formaldehyde assimilation, serine pathway
M00374 Dicarboxylate-hydroxybutyrate cycle
M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
Reaction
R00342 (S)-malate:NAD+ oxidoreductase
R07136 (2R)-3-sulfolactate:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K00024 mdh; malate dehydrogenase
00620 Pyruvate metabolism
K00024 mdh; malate dehydrogenase
00630 Glyoxylate and dicarboxylate metabolism
K00024 mdh; malate dehydrogenase
09102 Energy metabolism
00710 Carbon fixation in photosynthetic organisms
K00024 mdh; malate dehydrogenase
00720 Carbon fixation pathways in prokaryotes
K00024 mdh; malate dehydrogenase
00680 Methane metabolism
K00024 mdh; malate dehydrogenase
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
K00024 mdh; malate dehydrogenase
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.37 malate dehydrogenase
K00024 mdh; malate dehydrogenase
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Genes
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Taxonomy UniProt
Reference
Authors
Minarik P, Tomaskova N, Kollarova M, Antalik M
Title
Malate dehydrogenases--structure and function.
Journal
Gen Physiol Biophys 21:257-65 (2002)
Reference
Authors
Thompson H, Tersteegen A, Thauer RK, Hedderich R
Title
Two malate dehydrogenases in Methanobacterium thermoautotrophicum.
Journal
Sequence
Reference
Authors
Lee BI, Chang C, Cho SJ, Eom SH, Kim KK, Yu YG, Suh SW
Title
Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.
Journal
Sequence
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