Entry |
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Name |
Mycinamicin biosynthesis, malonyl-CoA + methylmalonyl-CoA => protomycinolide IV => mycinamicin II
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Definition |
K24528+K24559+K24560+K24561+K24562 K24529 K24292+K24530 K24531 K21540 K21539 K24390
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Diagram |
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Orthology |
mycA; protomycinolide IV synthase [RN: R12660] mycB; protomycinolide IV desosaminyltransferase [EC:2.4.1.-] [RN: R10876] mycCI; mycinamicin VIII C21 methyl hydroxylase [EC:1.14.-.-] [RN: R10875] mycCII; ferredoxin [RN: R10875] mycD; mycinamicin VII 6-deoxyallosyltransferase [EC:2.4.1.-] [RN: R10874] mycG; mycinamicin IV hydroxylase/epoxidase [EC:1.14.-.-] [RN: R10877 R10878] |
Class |
Pathway modules; Biosynthesis of terpenoids and polyketides; Macrolide biosynthesis
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Pathway |
map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
map01110 | Biosynthesis of secondary metabolites |
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Reaction |
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Compound |
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Reference |
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Authors |
Anzai Y, Li S, Chaulagain MR, Kinoshita K, Kato F, Montgomery J, Sherman DH. |
Title |
Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics. |
Journal |
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LinkDB |
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