| Entry |
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| Name |
PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine
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| Definition |
(K01495,K09007,K22391) K01737 K10026 K06920 (K06879,K09457)
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| Diagram |
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| Orthology |
6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC: 4.1.2.50] [RN: R09959] |
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| Class |
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
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| Pathway |
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| Reaction |
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| Compound |
| C05922 | Formamidopyrimidine nucleoside triphosphate |
| C05923 | 2,5-Diaminopyrimidine nucleoside triphosphate |
| C06148 | 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine |
| C04895 | 7,8-Dihydroneopterin 3'-triphosphate |
| C20239 | 6-Carboxy-5,6,7,8-tetrahydropterin |
| C20248 | 7-Carboxy-7-carbaguanine |
| C16675 | 7-Aminomethyl-7-carbaguanine |
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| Reference |
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| Authors |
McCarty RM, Somogyi A, Lin G, Jacobsen NE, Bandarian V |
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| Title |
The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps. |
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| Journal |
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| Reference |
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| Authors |
Hutinet G, Swarjo MA, de Crecy-Lagard V |
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| Title |
Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways. |
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| Journal |
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| LinkDB |
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