KEGG   MODULE: M01038
Entry
M01038            Pathway   Module                                 
Name
Staphyloxanthin biosynthesis, bacteria, farnesyl-PP => staphyloxanthin
Definition
K10208 K10209 K10210 K25072 K10211 K10212
Diagram
M01038  Staphyloxanthin biosynthesis, bacteria, farnesyl-PP => staphyloxanthin
M01038

Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Terpenoid biosynthesis
Pathway
map00906  Carotenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K10208  
crtM; 4,4'-diapophytoene synthase [EC:2.5.1.96] [RN:R00702 R09793]
K10209  
crtN; 4,4'-diapophytoene desaturase [EC:1.3.8.2] [RN:R07653]
K10210  
crtP; diapolycopene oxygenase [EC:1.14.99.44] [RN:R09727]
K25072  
crtNc; 4,4'-diapolycopenoate synthase [EC:1.2.99.10] [RN:R09728]
K10211  
crtQ; 4,4'-diaponeurosporenoate glycosyltransferase [EC:2.4.1.-] [RN:R07655]
K10212  
crtO; glycosyl-4,4'-diaponeurosporenoate acyltransferase [EC:2.3.1.-] [RN:R07656]
Complete
sau  Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA)
sav  Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
saw  Staphylococcus aureus subsp. aureus Mu3 (MRSA/hetero-VISA)
sah  Staphylococcus aureus subsp. aureus JH1 (MRSA/VSSA)
saj  Staphylococcus aureus subsp. aureus JH9 (MRSA/VISA)
sam  Staphylococcus aureus subsp. aureus MW2 (CA-MRSA)
sas  Staphylococcus aureus subsp. aureus MSSA476 (MSSA)
sac  Staphylococcus aureus subsp. aureus COL (MRSA)
sax  Staphylococcus aureus subsp. aureus USA300_TCH1516 (CA-MRSA)
saa  Staphylococcus aureus subsp. aureus USA300_FPR3757 (CA-MRSA)
sao  Staphylococcus aureus subsp. aureus NCTC8325
sae  Staphylococcus aureus subsp. aureus Newman
sad  Staphylococcus aureus subsp. aureus ED98
suu  Staphylococcus aureus subsp. aureus M013 (CA-MRSA)
suv  Staphylococcus aureus subsp. aureus VC40
sue  Staphylococcus aureus subsp. aureus ED133
suj  Staphylococcus aureus subsp. aureus JKD6159 (CA-MRSA)
suk  Staphylococcus aureus subsp. aureus JKD6008 (MRSA/VISA)
suc  Staphylococcus aureus subsp. aureus ECT-R 2 (MSSA)
sut  Staphylococcus aureus subsp. aureus T0131 (MRSA)
suq  Staphylococcus aureus subsp. aureus TCH60
suz  Staphylococcus aureus subsp. aureus 11819-97 (CA-MRSA)
sud  Staphylococcus aureus subsp. aureus 71193 (MSSA)
sux  Staphylococcus aureus subsp. aureus HO 5096 0412 (MRSA)
suw  Staphylococcus aureus subsp. aureus TW20 (MRSA)
sug  Staphylococcus aureus subsp. aureus ST398 (MRSA)
suf  Staphylococcus aureus subsp. aureus LGA251 (MRSA)
saua  Staphylococcus aureus subsp. aureus 55/2053
saue  Staphylococcus aureus subsp. aureus 6850 (MSSA)
saun  Staphylococcus aureus subsp. aureus CN1 (CA-MRSA)
saus  Staphylococcus aureus subsp. aureus SA40 (CA-MRSA)
sauu  Staphylococcus aureus subsp. aureus SA957 (CA-MRSA)
saug  Staphylococcus aureus subsp. aureus SA268 (CA-MRSA)
sauz  Staphylococcus aureus subsp. aureus Z172 (MRSA/VISA)
saut  Staphylococcus aureus subsp. aureus ST228/10388 (MRSA)
sauj  Staphylococcus aureus subsp. aureus ST228/10497 (MRSA)
sauk  Staphylococcus aureus subsp. aureus ST228/15532 (MRSA)
sauq  Staphylococcus aureus subsp. aureus ST228/16035 (MRSA)
sauv  Staphylococcus aureus subsp. aureus ST228/18412 (MRSA)
sauw  Staphylococcus aureus subsp. aureus ST228/16125 (MRSA)
saux  Staphylococcus aureus subsp. aureus ST228/18341 (MRSA)
sauy  Staphylococcus aureus subsp. aureus ST228/18583 (MRSA)
sauf  Staphylococcus aureus subsp. aureus FDAARGOS_5
sab  Staphylococcus aureus RF122
suy  Staphylococcus aureus 04-02981 (MRSA)
saub  Staphylococcus aureus 08BA02176 (LA-MRSA)
saum  Staphylococcus aureus M1 (MRSA)
sauc  Staphylococcus aureus CA-347 (MRSA)
saur  Staphylococcus aureus Bmb9393 (MRSA)
saui  Staphylococcus aureus USA300-ISMMS1 (MRSA)
saud  Staphylococcus aureus 502A
sha  Staphylococcus haemolyticus JCSC1435
slg  Staphylococcus lugdunensis HKU09-01
sln  Staphylococcus lugdunensis N920143
sxy  Staphylococcus xylosus HKUOPL8
sxl  Staphylococcus xylosus SMQ-121
sxo  Staphylococcus xylosus C2a
scap  Staphylococcus capitis subsp. capitis
seqo  Staphylococcus equorum
sury  Staphylococcus ureilyticus
snl  Staphylococcus nepalensis
shom  Staphylococcus hominis
scar  Staphylococcus caprae
sarl  Staphylococcus arlettae
spic  Staphylococcus piscifermentans
ssh  Staphylococcus schweitzeri
ssim  Staphylococcus simiae
sdb  Staphylococcus debuckii
sllo  Staphylococcus lloydii
spsd  Staphylococcus shinii
stas  Staphylococcus taiwanensis
sdev  Staphylococcus devriesei
srot  Staphylococcus roterodami
sgai  Staphylococcus gallinarum
ssuc  Staphylococcus succinus
sscu  Mammaliicoccus sciuri
mlen  Mammaliicoccus lentus
 » show all
Reaction
R00702  
R09793  
R07653  
R09727  
R09728  
R07655  
R07656  
Compound
C00448  trans,trans-Farnesyl diphosphate
C03428  Presqualene diphosphate
C16144  4,4'-Diapophytoene
C16145  4,4'-Diaponeurosporene
C19839  4,4'-Diaponeurosporen-4-al
C16146  4,4'-Diaponeurosporenic acid
C16147  Glucosyl-4,4'-diaponeurosporenoate
C16148  Staphyloxanthin
Reference
PMID:22535955
  Authors
Kim SH, Lee PC
  Title
Functional expression and extension of staphylococcal staphyloxanthin biosynthetic pathway in Escherichia coli.
  Journal
J Biol Chem 287:21575-83 (2012)
DOI:10.1074/jbc.M112.343020
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