Entry |
|
Name |
Mutation-activated BRAF to ERK signaling pathway
|
Definition |
BRAF* -> MEK -> ERK |
Expanded |
673v1 -> (5604,5605) -> (5594,5595) |
Class |
|
Type |
Variant
|
Pathway |
|
Disease |
|
Gene |
673 | BRAF; B-Raf proto-oncogene, serine/threonine kinase |
5604 | MAP2K1; mitogen-activated protein kinase kinase 1 |
5605 | MAP2K2; mitogen-activated protein kinase kinase 2 |
5594 | MAPK1; mitogen-activated protein kinase 1 |
5595 | MAPK3; mitogen-activated protein kinase 3 |
|
Variant |
673v1 (BRAF*) BRAF mutation
|
Reference |
|
Authors |
Chiloeches A, Marais R. |
Title |
Is BRAF the Achilles' Heel of thyroid cancer? |
Journal |
|
Reference |
|
Authors |
Kondo T, Ezzat S, Asa SL. |
Title |
Pathogenetic mechanisms in thyroid follicular-cell neoplasia. |
Journal |
|
LinkDB |
|