Entry |
|
Name |
HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
|
Definition |
Env -> (CXCR4,CCR5) -> GNB/G |
Expanded |
K19287 -> (7852,1234) -> (2782,2783,2784,59345,10681,54331,2785,2786,2787,2788,94235,2790,2791,55970,51764,2792,2793) |
Class |
nt06533 Chemokine signaling
nt06161 Human immunodeficiency virus 1 (HIV-1)
|
Type |
Pathogen
|
Pathway |
hsa05170 | Human immunodeficiency virus 1 infection |
|
Disease |
|
Gene |
7852 | CXCR4; C-X-C motif chemokine receptor 4 |
1234 | CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) |
2782 | GNB1; G protein subunit beta 1 |
2783 | GNB2; G protein subunit beta 2 |
2784 | GNB3; G protein subunit beta 3 |
59345 | GNB4; G protein subunit beta 4 |
10681 | GNB5; G protein subunit beta 5 |
54331 | GNG2; G protein subunit gamma 2 |
2785 | GNG3; G protein subunit gamma 3 |
2786 | GNG4; G protein subunit gamma 4 |
2787 | GNG5; G protein subunit gamma 5 |
2788 | GNG7; G protein subunit gamma 7 |
94235 | GNG8; G protein subunit gamma 8 |
2790 | GNG10; G protein subunit gamma 10 |
2791 | GNG11; G protein subunit gamma 11 |
55970 | GNG12; G protein subunit gamma 12 |
51764 | GNG13; G protein subunit gamma 13 |
2792 | GNGT1; G protein subunit gamma transducin 1 |
2793 | GNGT2; G protein subunit gamma transducin 2 |
|
Perturbant |
K19287 (Env) | gp160; HIV-1 envelope glycoprotein gp160 |
|
Reference |
|
Authors |
Vorster PJ, Guo J, Yoder A, Wang W, Zheng Y, Xu X, Yu D, Spear M, Wu Y |
Title |
LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection. |
Journal |
|
Reference |
|
Authors |
Evans VA, Khoury G, Saleh S, Cameron PU, Lewin SR |
Title |
HIV persistence: chemokines and their signalling pathways. |
Journal |
|
Reference |
|
Authors |
Wu Y, Yoder A |
Title |
Chemokine coreceptor signaling in HIV-1 infection and pathogenesis. |
Journal |
|
LinkDB |
|