KEGG T01001: 2783

Homo sapiens (human): 2783

Entry

2783              CDS       T01001

Symbol

GNB2, HG2C1, SSS4, NEDHYDF

Name

(RefSeq) G protein subunit beta 2

K04537

guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

Organism

hsa Homo sapiens (human)

Pathway

hsa04014

Ras signaling pathway

hsa04062

Chemokine signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04371

Apelin signaling pathway

hsa04713

Circadian entrainment

hsa04723

Retrograde endocannabinoid signaling

hsa04724

Glutamatergic synapse

hsa04725

Cholinergic synapse

hsa04726

Serotonergic synapse

hsa04727

GABAergic synapse

hsa04728

Dopaminergic synapse

hsa04926

Relaxin signaling pathway

hsa05032

Morphine addiction

hsa05034

Alcoholism

hsa05163

Human cytomegalovirus infection

hsa05167

Kaposi sarcoma-associated herpesvirus infection

hsa05170

Human immunodeficiency virus 1 infection

hsa05200

Pathways in cancer

Network

nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling (cancer)
nt06530  PI3K signaling
nt06533  Chemokine signaling

Element

N00152

CXCR-GNB/G-ERK signaling pathway

N00153

CCR/CXCR-GNB/G-PI3K-RAC signaling pathway

N00154

CXCR-GNB/G-PI3K-AKT signaling pathway

N00157

KSHV vGPCR to GNB/G-ERK signaling pathway

N00158

KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway

N00178

KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway

N00399

CCR2-GNB/G-PI3K-NFKB signaling pathway

N00400

HCMV US28 to GNB/G-PI3K-NFKB signaling pathway

N00408

LPAR-GNB/G-Rho signaling pathway

N00409

HCMV UL33 to GNB/G-Rho signaling pathway

N00413

CXCR4-GNB/G-PLCB-PKC signaling pathway

N00428

CCR5-GNB/G-PLCB/G-PKC signaling pathway

N00433

CXCR4-GNB/G-RAC signaling pathway

N00434

HIV gp120 to CXCR4-GNB/G-RAC signaling pathway

N01657

GPCR-PI3K signaling pathway

N01746

CCR/CXCR-GNB/G-PI3K signaling pathway

N01769

CCR5-GNB/G-PLCB/G signaling pathway

N01770

CCR2-GNB/G-PI3K signaling pathway

N01771

CXCR4-GNB/G signaling pathway

Disease

H00729

Sick sinus syndrome

H02705

Neurodevelopmental disorder with glutamatergic synapse dysfunction

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2783 (GNB2)
   04371 Apelin signaling pathway
    2783 (GNB2)
   04151 PI3K-Akt signaling pathway
    2783 (GNB2)
09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2783 (GNB2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2783 (GNB2)
  09156 Nervous system
   04724 Glutamatergic synapse
    2783 (GNB2)
   04727 GABAergic synapse
    2783 (GNB2)
   04725 Cholinergic synapse
    2783 (GNB2)
   04728 Dopaminergic synapse
    2783 (GNB2)
   04726 Serotonergic synapse
    2783 (GNB2)
   04723 Retrograde endocannabinoid signaling
    2783 (GNB2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2783 (GNB2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2783 (GNB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2783 (GNB2)
   05163 Human cytomegalovirus infection
    2783 (GNB2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2783 (GNB2)
  09165 Substance dependence
   05032 Morphine addiction
    2783 (GNB2)
   05034 Alcoholism
    2783 (GNB2)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2783 (GNB2)
   04031 GTP-binding proteins [BR:hsa04031]
    2783 (GNB2)
Exosome [BR:hsa04147]
Exosomal proteins
  Proteins found in most exosomes
   2783 (GNB2)
GTP-binding proteins [BR:hsa04031]
Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    2783 (GNB2)

SSDB

Motif

Pfam:

WD40 ANAPC4_WD40 NBCH_WD40 WD40_like Acanthaporin

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

LinkDB

Position

7:100673740..100679169

AA seq 340 aa
MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNI
CSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGF
AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA
FTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN

NT seq 1023 nt +upstreamnt +downstreamnt
atgagtgagctggagcaactgagacaggaggccgagcagctccggaaccagatccgggat
gcccgaaaagcatgtggggactcaacactgacccagatcacagctgggctggacccagtg
gggagaatccagatgaggacccggaggaccctccgtgggcacctggcaaagatctatgcc
atgcactgggggaccgactcaaggctgctggtcagcgcctcccaggatgggaagctcatc
atctgggacagctacaccaccaacaaggtccacgccatcccgctgcgctcctcctgggta
atgacctgtgcctacgcgccctcagggaactttgtggcctgtggggggttggacaacatc
tgctccatctacagcctcaagacccgcgagggcaacgtcagggtcagccgggagctgcct
ggccacactgggtacctgtcgtgttgccgcttcctggatgacaaccaaatcatcaccagc
tctggggataccacctgtgccctgtgggacattgagacaggccagcagacagtgggtttt
gctggacacagtggggatgtgatgtccctgtccctggcccccgatggccgcacgtttgtg
tcaggcgcctgtgatgcctctatcaagctgtgggacgtgcgggattccatgtgccgacag
accttcatcggccatgaatccgacatcaatgcagtggctttcttccccaacggctacgcc
ttcaccaccggctctgacgacgccacgtgccgcctcttcgacctgcgggccgatcaggag
ctcctcatgtactcccatgacaacatcatctgtggcatcacctctgttgccttctcgcgc
agcggacggctgctgctcgctggctacgacgacttcaactgcaacatctgggatgccatg
aagggcgaccgtgcaggagtcctcgctggccacgacaaccgcgtgagctgcctcggggtc
accgacgatggcatggctgtggccacgggctcctgggactccttcctcaagatctggaac
taa

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