KEGG   ORTHOLOGY: K19287
Entry
K19287                      KO                                     

Name
env, gp160
Definition
HIV envelope glycoprotein gp160
Pathway
ko03230  Viral genome structure
Network
nt06123  TNF signaling (viruses and bacteria)
nt06124  Chemokine signaling (viruses)
nt06150  Cytokine-cytokine receptor interaction (viruses)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
  Element
N00431  HIV gp120 to CXCR4-GNAI-PI3K-BAD signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
N00441  HIV gp120 to TNF-NFKB signaling pathway
N01211  HIV gp120 to CCR5 signaling
N01254  HIV gp120 to CXCR4 signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K19287  env, gp160; HIV envelope glycoprotein gp160
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K19287  env, gp160; HIV envelope glycoprotein gp160
  09185 Viral protein families
   03200 Viral proteins
    K19287  env, gp160; HIV envelope glycoprotein gp160
   03210 Viral fusion proteins
    K19287  env, gp160; HIV envelope glycoprotein gp160
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Microbial pathogens
   K19287  env, gp160; HIV envelope glycoprotein gp160
Viral proteins [BR:ko03200]
 ssRNA-RT viruses
  Human immunodeficiency virus
   K19287  env, gp160; HIV envelope glycoprotein gp160
Viral fusion proteins [BR:ko03210]
 Class I fusion proteins
  Retroviridae
   K19287  env, gp160; HIV envelope glycoprotein gp160
Genes
VG: 1490007(env) 155971(env) 1724717(HIV2gp7) 956110(env)
Reference
PMID:2450679
  Authors
McCune JM, Rabin LB, Feinberg MB, Lieberman M, Kosek JC, Reyes GR, Weissman IL
  Title
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus.
  Journal
Cell 53:55-67 (1988)
DOI:10.1016/0092-8674(88)90487-4
Reference
  Authors
Papuashvili MN, Novokhatsky AS, Shcherbakova TI
  Title
Characteristics of HIV-1 env V3 loop sequences for subtype A1 variant spread in Eastern Europe.
  Journal
Infect Genet Evol 5:45-53 (2005)
DOI:10.1016/j.meegid.2004.06.003
  Sequence
[vg:155971]
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