| Entry |
|
|---|
| Name |
HIV Vpr/Tat to TNF-JNK signaling pathway
|
|---|
| Definition |
(Vpr,Tat) -> JNK -> AP1 |
|---|
| Expanded |
(K22202,K19258) -> (5599,5601,5602) -> (2353,3725) |
|---|
| Type |
Pathogen
|
|---|
| Pathway |
| hsa05170 | Human immunodeficiency virus 1 infection |
|
|---|
| Disease |
|
|---|
| Gene |
| 5599 | MAPK8; mitogen-activated protein kinase 8 |
| 5601 | MAPK9; mitogen-activated protein kinase 9 |
| 5602 | MAPK10; mitogen-activated protein kinase 10 |
| 2353 | FOS; Fos proto-oncogene, AP-1 transcription factor subunit |
| 3725 | JUN; Jun proto-oncogene, AP-1 transcription factor subunit |
|
|---|
| Perturbant |
| K22202 (Vpr) | vpr; HIV-1 virus protein R |
| K19258 (Tat) | tat; HIV-1 protein Tat |
|
|---|
| Reference |
|
|---|
| Authors |
Pasquereau S, Kumar A, Herbein G |
|---|
| Title |
Targeting TNF and TNF Receptor Pathway in HIV-1 Infection: from Immune Activation to Viral Reservoirs. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Herbein G, Khan KA |
|---|
| Title |
Is HIV infection a TNF receptor signalling-driven disease? |
|---|
| Journal |
|
|---|
| LinkDB |
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|---|
