| Entry |
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| Name |
HTLV-1 Tax to NFKB signaling pathway
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| Definition |
TAX -> IKK -> NFKBIA -> NFKB |
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| Expanded |
K21857 -> (1147+3551+8517) -> 4792 -> (4790+5970) |
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| Class |
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| Type |
Pathogen
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| Pathway |
| hsa05166 | Human T-cell leukemia virus 1 infection |
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| Disease |
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| Gene |
| 1147 | CHUK; conserved helix-loop-helix ubiquitous kinase |
| 3551 | IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta |
| 8517 | IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma |
| 4792 | NFKBIA; NFKB inhibitor alpha |
| 4790 | NFKB1; nuclear factor kappa B subunit 1 |
| 5970 | RELA; RELA proto-oncogene, NF-kB subunit |
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| Perturbant |
| K21857 (TAX) | tax; HTLV protein Tax-1 |
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| Reference |
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| Authors |
Harhaj EW, Harhaj NS |
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| Title |
Mechanisms of persistent NF-kappaB activation by HTLV-I tax. |
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| Journal |
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| Reference |
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| Authors |
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L |
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| Title |
The HTLV-1 Tax interactome. |
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| Journal |
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| Reference |
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| Authors |
Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET Jr, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC |
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| Title |
Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. |
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| Journal |
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| Reference |
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| Authors |
Sun SC, Yamaoka S |
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| Title |
Activation of NF-kappaB by HTLV-I and implications for cell transformation. |
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| Journal |
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| LinkDB |
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