| Entry |
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| Name |
HBV HBx to cell cycle G1/S
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| Definition |
X -> (CCNE+CDK2) -> RB1 // E2F |
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| Expanded |
K21854 -> ((898,9134)+1017) -> 5925 // (1869,1870,1871) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
| H00048 | Hepatocellular carcinoma |
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| Gene |
| 1017 | CDK2; cyclin dependent kinase 2 |
| 5925 | RB1; RB transcriptional corepressor 1 |
| 1869 | E2F1; E2F transcription factor 1 |
| 1870 | E2F2; E2F transcription factor 2 |
| 1871 | E2F3; E2F transcription factor 3 |
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| Perturbant |
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| Reference |
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| Authors |
Zhang X, Zhang H, Ye L |
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| Title |
Effects of hepatitis B virus X protein on the development of liver cancer. |
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| Journal |
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| Reference |
|
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| Authors |
Mukherji A, Janbandhu VC, Kumar V |
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| Title |
HBx-dependent cell cycle deregulation involves interaction with cyclin E/A-cdk2 complex and destabilization of p27Kip1. |
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| Journal |
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| LinkDB |
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