KEGG   ORTHOLOGY: K21854
Entry
K21854                      KO                                     
Symbol
X
Name
Orthohepadnavirus protein X
Pathway
map03230  Viral genome structure
map05161  Hepatitis B
map05203  Viral carcinogenesis
Network
nt06162  Hepatitis B virus (HBV)
nt06214  PI3K signaling (cancer)
nt06263  Hepatocellular carcinoma
nt06507  TGFB signaling
nt06518  JAK-STAT signaling
nt06519  RLR signaling
nt06524  Apoptosis
  Element
N00267  HBV HBx to PI3K signaling pathway
N00268  HBV HBx to RIG-I-like receptor signaling pathway
N00531  HBV HBx to TGF-beta signaling pathway
N00532  HBV HBx to Egr-mediated transcription
N00533  HBV HBx to Crosstalk between extrinsic and intrinsic apoptotic pathways
N00534  HBV HBx to Crosstalk between extrinsic and intrinsic apoptotic pathways
N00535  HBV HBx to p53-mediated transcription
N00537  HBV HBx to cell cycle G1/S
N00539  HBV HBx to Ca2+-PYK2-RAS-ERK signaling pathway
N00540  HBV HBx to RAS-ERK signaling pathway
N00541  HBV HBx to RAS-ERK signaling pathway
N00543  HBV HBx to JNK signaling pathway
N00544  HBV HBx to CREB-mediated transcription
N00545  HBV HBx to ERK signaling pathway
N00548  HBV HBx to Jak-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K21854  X; Orthohepadnavirus protein X
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K21854  X; Orthohepadnavirus protein X
  09172 Infectious disease: viral
   05161 Hepatitis B
    K21854  X; Orthohepadnavirus protein X
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21854  X; Orthohepadnavirus protein X
Viral proteins [BR:ko03200]
 dsDNA-RT viruses
  Hepatitis B virus
   K21854  X; Orthohepadnavirus protein X
Genes
VG: 1488457(GSHVgp4) 15042021(K202_gp3) 19737424(HM84_gp3) 19737429(HM82_gp3) 19737434(HM83_gp3) 2546422(WhBvgp3) 26101582(AR657_gp4) 37617585(D1R25_gp3) 40526804(FLA63_gp5) 41701928(EXK74_gp3) 80512047(QJ742_gp3) 944566(X)
Reference
PMID:26316075
  Authors
Idrissi ME, Hachem H, Koering C, Merle P, Thenoz M, Mortreux F, Wattel E
  Title
HBx triggers either cellular senescence or cell proliferation depending on cellular phenotype.
  Journal
J Viral Hepat 23:130-8 (2016)
DOI:10.1111/jvh.12450
  Sequence
[vg:944566]
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