KEGG   NETWORK: N00561
Entry
N00561                      Network                                
Name
HSV ICP0 to TLR2/4-NFKB signaling pathway
Definition
ICP0 -| MYD88
  Expanded
K19436 -| 4615
Class
nt06121 TLR signaling (viruses and bacteria)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
4615  MYD88; MYD88, innate immune signal transduction adaptor
Perturbant
K19436 (ICP0)  ICP0; Simplexvirus E3 ubiquitin-protein ligase ICP0
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
van Lint AL, Murawski MR, Goodbody RE, Severa M, Fitzgerald KA, Finberg RW, Knipe DM, Kurt-Jones EA
  Title
Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
  Journal
J Virol 84:10802-11 (2010)
DOI:10.1128/JVI.00063-10
Reference
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
LinkDB

DBGET integrated database retrieval system