KEGG   NETWORK: N00851
Entry
N00851                      Network                                
Name
Leucine degradation
Definition
IV-CoA -- (IVD,ACADM) >> MCCC1/2 >> AUH >> (HMGCL,HMGCLL1) -> AcCoA
  Expanded
C02939 -- (3712,34) >> (56922+64087) >> 549 >> (3155,54511) -> C00024
Class
nt06024 Valine, leucine and isoleucine degradation
Type
Reference
Pathway
hsa00280  Valine, leucine and isoleucine degradation
Gene
3712  IVD; isovaleryl-CoA dehydrogenase
34  ACADM; acyl-CoA dehydrogenase medium chain
56922  MCCC1; methylcrotonoyl-CoA carboxylase 1
64087  MCCC2; methylcrotonoyl-CoA carboxylase 2
549  AUH; AU RNA binding methylglutaconyl-CoA hydratase
3155  HMGCL; 3-hydroxy-3-methylglutaryl-CoA lyase
54511  HMGCLL1; 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1
Metabolite
C02939  Isovaleryl-CoA
C00024  Acetyl-CoA
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