Entry
Name
FSHR-GNAS-PKA signaling pathway
Definition
(CGA+FSHB) -> FSHR -> GNAS -> ADCY -> cAMP -> PKA
Expanded
(1081+2488) -> 2492 -> 2778 -> (107,108,109,196883,111,112,113,114,115) -> C00575 -> (5566+5567+5568)
Class
nt06323 KISS1-GnRH-LH/FSH-E2 signaling
Type
Reference
Pathway
Gene
1081 CGA; glycoprotein hormones, alpha polypeptide
2488 FSHB; follicle stimulating hormone subunit beta
2492 FSHR; follicle stimulating hormone receptor
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
Metabolite
Reference
Authors
Amory JK, Bremner W
Title
Endocrine regulation of testicular function in men: implications for contraceptive development.
Journal
Reference
Authors
Walker WH, Cheng J
Title
FSH and testosterone signaling in Sertoli cells.
Journal
Reference
Authors
Loss ES, Jacobus AP, Wassermann GF
Title
Rapid signaling responses in Sertoli cell membranes induced by follicle stimulating hormone and testosterone: calcium inflow and electrophysiological changes.
Journal
LinkDB
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